CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C03801 | BRD-K61120504 | NSC636819 | KDM4A|KDM4B | histone demethylase inhibitor | Details | |
| C03802 | BRD-K74371986 | NSI-189 | neurotrophic agent | Details | ||
| C03803 | BRD-A40413915 | NTNCB | NPY5R | neuropeptide receptor antagonist | Details | |
| C03804 | BRD-K07788774 | NTRC-824 | NTSR2 | neurotensin receptor antagonist | Details | |
| C03805 | BRD-K54708045 | nTZDpa | PPARG | PPAR receptor agonist | Details | |
| C03806 | BRD-K54098378 | NT157 | IGF1R | IGF-1 inhibitor | Details | |
| C03807 | BRD-K48692744 | NU-1025 | PARP1 | PARP inhibitor | Details | |
| C03808 | BRD-K20976221 | NU-2058 | CCNA2|CDK2 | cyclin D inhibitor | Details | |
| C03809 | BRD-K09537769 | NU-7026 | PRKDC | DNA dependent protein kinase inhibitor; mTOR inhibitor; PI3K inhibitor | Details | |
| C03810 | BRD-K00337317 | NU-7441 | PRKDC | DNA dependent protein kinase inhibitor | Details | |
| C03811 | BRD-A96466199 | nuclomedone | immunosuppressant | Details | ||
| C03812 | BRD-A12230535 | nutlin-3 | MDM2|TP53 | MDM inhibitor | Details | |
| C03813 | BRD-K03294269 | NU6027 | CCNA2|CDK2 | CDK inhibitor | Details | |
| C03814 | BRD-K15179513 | NVP-ADW742 | IGF1R | insulin growth factor receptor inhibitor | Details | |
| C03815 | BRD-K24696047 | NVP-AEW541 | IGF1R|INSR | IGF-1 inhibitor | Details | |
| C03816 | BRD-K41859756 | NVP-AUY922 | HSP90AA1|HSP90AB1 | HSP inhibitor | Details | |
| C03817 | BRD-K12184916 | NVP-BEZ235 | ATR|MTOR|PIK3CA|PIK3CD|PIK3CG | mTOR inhibitor; PI3K inhibitor | Details | |
| C03818 | BRD-K42728290 | NVP-BGJ398 | FGFR1|FGFR2|FGFR3|FGFR4|KDR | FGFR inhibitor | Details | |
| C03819 | BRD-K79259477 | NVP-BHG712 | EPHB4 | ephrin inhibitor | Details | |
| C03820 | BRD-K02017404 | NVP-BSK805 | JAK2 | JAK inhibitor | Details | |
| C03821 | BRD-K77943374 | NVP-BVU972 | MET | MET inhibitor | Details | |
| C03822 | BRD-K77396579 | NVP-DPP728 | DPP4 | dipeptidyl peptidase inhibitor | Details | |
| C03823 | BRD-K67915505 | NVP-HSP990 | HSP90AA1|HSP90AB1 | HSP inhibitor | Details | |
| C03824 | BRD-K21025364 | NVP-TAE226 | PTK2 | protein tyrosine kinase inhibitor | Details | |
| C03825 | BRD-K50140147 | NVP-TAE684 | ALK|INSR | ALK tyrosine kinase receptor inhibitor | Details | |
| C03826 | BRD-K87454346 | NVP-TNKS656 | TNKS2 | tankyrase inhibitor | Details | |
| C03827 | BRD-K01573278 | NVP-231 | CERK | ceramidase inhibitor | Details | |
| C03828 | BRD-K28132190 | NVS-PAK1-1 | PAK1 | p21 activated kinase inhibitor | Details | |
| C03829 | BRD-K46133855 | NXY-059 | free radical scavenger | Details | ||
| C03830 | BRD-K21656326 | nystatin | fungal ergosterol inhibitor | Details | ||
| C03831 | BRD-K41143549 | N20C | glutamate receptor antagonist | Details | ||
| C03832 | BRD-K60150510 | N6-cyclopentyladenosine | ADORA1|ADORA2A|ADORA2B|ADORA3|SLC29A1 | adenosine receptor agonist | Details | |
| C03833 | BRD-K81807412 | N6-methyladenosine | Details | |||
| C03834 | BRD-K82522873 | N6022 | ADH5 | alcohol dehydrogenase inhibitor | Details | |
| C03835 | BRD-K63247785 | o-acetyl-L-serine | PTGS1 | Details | ||
| C03836 | BRD-K36998189 | o-mercapto-benzoic-acid | Details | |||
| C03837 | BRD-K18316707 | O-1918 | cannabinoid receptor antagonist | Details | ||
| C03838 | BRD-K46384212 | o-3M3FBS | phospholipase activator | Details | ||
| C03839 | BRD-K10878147 | OAC1 | Oct activator | Details | ||
| C03840 | BRD-K18305454 | OAC2 | POU5F1 | Oct activator | Details | |
| C03841 | BRD-K15600710 | obatoclax | BCL2 | BCL inhibitor | Details | |
| C03842 | BRD-A75838038 | obeticholic-acid | NR1H4 | FXR agonist | Details | |
| C03843 | BRD-K33588785 | obidoxime | ACHE | cholinesterase reactivator | Details | |
| C03844 | BRD-K92524032 | ochromycinone | STAT3 | STAT inhibitor | Details | |
| C03845 | BRD-K92581468 | ocinaplon | GABRA1|GABRA2|GABRA3|GABRA5 | GABA receptor modulator | Details | |
| C03846 | BRD-K22097830 | OCO-1112 | cholesterol inhibitor | Details | ||
| C03847 | BRD-K20501889 | octadecan-1-ol | Details | |||
| C03848 | BRD-K73201113 | octamethyltrisiloxane | Details | |||
| C03849 | BRD-K04568635 | octenidine | membrane integrity inhibitor | Details | ||
| C03850 | BRD-K19972289 | octinoxate | Details | |||
| C03851 | BRD-K95161686 | octisalate | Details | |||
| C03852 | BRD-K39023557 | octocrylene | Details | |||
| C03853 | BRD-A37873789 | octodrine | antitumor agent | Details | ||
| C03854 | BRD-A14240607 | octopamine | F10|TAAR1 | trace amine associated receptor agonist | Details | |
| C03855 | BRD-A64173453 | octreotide | SSTR1|SSTR2|SSTR3|SSTR5 | somatostatin receptor agonist | Details | |
| C03856 | BRD-K36463073 | OC000459 | PTGDR2 | CRTH receptor antagonist | Details | |
| C03857 | BRD-K22822991 | odanacatib | CTSK | cathepsin inhibitor | Details | |
| C03858 | BRD-A44971162 | ODM-201 | AR | androgen receptor antagonist | Details | |
| C03859 | BRD-K26015241 | ODQ | GUCY1A2|GUCY1A3|GUCY1B3 | guanylyl cyclase inhibitor | Details | |
| C03860 | BRD-K92658264 | OF-1 | BRD1 | bromodomain inhibitor | Details | |
| C03861 | BRD-A24228527 | ofloxacin | TOP2A | bacterial DNA gyrase inhibitor | Details | |
| C03862 | BRD-K26349472 | OG-L002 | KDM1A | histone lysine demethylase inhibitor | Details | |
| C03863 | BRD-K92303087 | oglemilast | phosphodiesterase inhibitor | Details | ||
| C03864 | BRD-K94083718 | OICR-9429 | WDR5 | WDR5/MLL interaction inhibitor | Details | |
| C03865 | BRD-K18895904 | olanzapine | ADRA1A|ADRA1B|ADRA2A|ADRA2B|ADRA2C|ADRB1|ADRB2|ADRB3|CHRM1|CHRM2|CHRM3|CHRM4|CHRM5|DRD1|DRD2|DRD3|DRD4|DRD5|GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRB1|GABRB2|GABRB3|GABRD|GABRE|GABRG1|GABRG2|GABRG3|GABRP|GABRQ|HRH1|HRH2|HRH4|HTR1A|HTR1B|HTR1D|HTR1E|HTR1F|HTR2A|HTR2B|HTR2C|HTR3A|HTR5A|HTR6|HTR7 | dopamine receptor antagonist; serotonin receptor antagonist | Details | |
| C03866 | BRD-K02113016 | olaparib | PARP1|PARP2 | PARP inhibitor | Details | |
| C03867 | BRD-K95523387 | OLDA | GPR119 | TRPV agonist | Details | |
| C03868 | BRD-K06644925 | oleamide | HTR7|PLA2G2A | cannabinoid receptor agonist | Details | |
| C03869 | BRD-K98006098 | oleandrin | Na/K-ATPase inhibitor | Details | ||
| C03870 | BRD-K90647725 | oleanolic-acid | GPBAR1 | G protein-coupled receptor agonist | Details | |
| C03871 | BRD-K66956375 | oleoylethanolamide | CNR1|GPR119|GPR55|PPARA | cannabinoid receptor agonist; glucose dependent insulinotropic receptor agonist; potassium channel blocker; PPAR receptor agonist | Details | |
| C03872 | BRD-K18210059 | olesoxime | apoptosis stimulant | Details | ||
| C03873 | BRD-A00842753 | oleuropein | GPER1 | estrogen receptor agonist | Details | |
| C03874 | BRD-A81541225 | oligomycin-a | ATP5A1 | ATP synthase inhibitor; ATPase inhibitor | Details | |
| C03875 | BRD-K83144676 | olmesartan | AGTR1 | angiotensin receptor antagonist | Details | |
| C03876 | BRD-K78485176 | olmesartan-medoxomil | AGTR1 | angiotensin receptor antagonist | Details | |
| C03877 | BRD-K60421517 | olmutinib | BTK|EGFR | EGFR inhibitor; Bruton's tyrosine kinase (BTK) inhibitor | Details | |
| C03878 | BRD-K82731415 | olomoucine | CDK1|CDK2|CDK5|MAPK1 | CDK inhibitor | Details | |
| C03879 | BRD-K67637637 | olopatadine | HRH1|S100A1|S100A12|S100A13|S100A2|S100B | histamine receptor antagonist | Details | |
| C03880 | BRD-K20745393 | olprinone | PDE3A | phosphodiesterase inhibitor | Details | |
| C03881 | BRD-K57853941 | olsalazine | IFNG|TPMT | cyclooxygenase inhibitor | Details | |
| C03882 | BRD-K86972824 | oltipraz | ANG | nuclear factor erythroid derived; like (NRF2) activator | Details | |
| C03883 | BRD-K31560319 | olvanil | CNR1|GPR119|TRPV1 | TRPV agonist | Details | |
| C03884 | BRD-A72591750 | omadacycline | bacterial 30S ribosomal subunit inhibitor | Details | ||
| C03885 | BRD-K14171291 | omarigliptin | DPP4 | dipeptidyl peptidase inhibitor | Details | |
| C03886 | BRD-K11072003 | ombitasvir | HCV inhibitor | Details | ||
| C03887 | BRD-K48830578 | OMDM-2 | GPR119 | FAAH inhibitor | Details | |
| C03888 | BRD-K36680103 | omecamtiv-mecarbil | MYBPC3 | cardiac myosin activator | Details | |
| C03889 | BRD-K53156781 | omega-(4-Iodophenyl)pentadecanoic acid | Details | |||
| C03890 | BRD-K31139048 | omega-3-acid-esters | cholesterol inhibitor | Details | ||
| C03891 | BRD-A55962179 | omeprazole | ATP4A|CLCN2 | ATPase inhibitor | Details | |
| C03892 | BRD-A56892734 | omeprazole-magnesium | ATP4A|ATP4B | proton pump inhibitor | Details | |
| C03893 | BRD-K69035426 | omeprazole-sulfide | ATPase inhibitor | Details | ||
| C03894 | BRD-K55790047 | ON-01500 | apoptosis stimulant | Details | ||
| C03895 | BRD-K43449605 | oncrasin-1 | apoptosis stimulant | Details | ||
| C03896 | BRD-K58529924 | ONC201 | TNFSF10 | AKT inhibitor; MAP kinase inhibitor | Details | |
| C03897 | BRD-A19736161 | ondansetron | HTR1A|HTR1B|HTR3A|HTR3B|HTR4|OPRM1 | serotonin receptor antagonist | Details | |
| C03898 | BRD-A80567330 | ONO-AE3-208 | PTGER4 | prostanoid receptor antagonist | Details | |
| C03899 | BRD-A13689093 | ONO-4059 | BTK | Bruton's tyrosine kinase (BTK) inhibitor | Details | |
| C03900 | BRD-K58894520 | ONO-4817 | MMP8 | matrix metalloprotease inhibitor | Details |