CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C05001 | BRD-K77251551 | sodium-picosulfate | Details | |||
| C05002 | BRD-K93632104 | sodium-salicylate | ASIC3|PTGS1|PTGS2 | prostanoid receptor antagonist | Details | |
| C05003 | BRD-A60786380 | sodium-stibogluconate | PTPN6|TOP1 | tyrosine phosphatase inhibitor | Details | |
| C05004 | BRD-K84798689 | sodium-tanshinone-ii-a-sulfonate | potassium channel activator | Details | ||
| C05005 | BRD-A55664972 | sodium-tetradecyl-sulfate | PROC|PROS1 | Details | ||
| C05006 | BRD-K01039503 | sofalcone | CBR1 | mucus protecting agent | Details | |
| C05007 | BRD-K05674516 | sofosbuvir | RNA polymerase inhibitor | Details | ||
| C05008 | BRD-A65562236 | solamargine | apoptosis inhibitor | Details | ||
| C05009 | BRD-K69215269 | solcitinib | JAK1 | JAK inhibitor | Details | |
| C05010 | BRD-K24723746 | solifenacin-succinate | CHRM1|CHRM2|CHRM3|CHRM4|CHRM5 | acetylcholine receptor antagonist | Details | |
| C05011 | BRD-K32256160 | solithromycin | protein synthesis inhibitor | Details | ||
| C05012 | BRD-K85764479 | somantadine | antiviral | Details | ||
| C05013 | BRD-K14681867 | somatostatin | OPRD1|OPRM1|SSTR1|SSTR2|SSTR3|SSTR4|SSTR5 | somatostatin receptor agonist | Details | |
| C05014 | BRD-K19796430 | sonidegib | SMO | smoothened receptor antagonist | Details | |
| C05015 | BRD-K66845263 | sophocarpine | Details | |||
| C05016 | BRD-K23984367 | sorafenib | BRAF|DDR2|FGFR1|FLT1|FLT3|FLT4|KDR|KIT|PDGFRB|RAF1|RET | FLT3 inhibitor; KIT inhibitor; PDGFR tyrosine kinase receptor inhibitor; RAF inhibitor; RET tyrosine kinase inhibitor; VEGFR inhibitor | Details | |
| C05017 | BRD-K55892330 | sorbic-acid | Details | |||
| C05018 | BRD-A89164055 | sorbinil | AKR1B1 | aldose reductase inhibitor | Details | |
| C05019 | BRD-A70197423 | sorbitan-monostearate | Details | |||
| C05020 | BRD-K66035042 | sorbitol | mucolytic agent | Details | ||
| C05021 | BRD-K05850076 | sotagliflozin | SLC5A1|SLC5A2 | sodium/glucose cotransporter inhibitor | Details | |
| C05022 | BRD-A33168282 | sotalol | ADRB1|ADRB2|KCNH2 | adrenergic receptor antagonist | Details | |
| C05023 | BRD-K16761703 | sotrastaurin | PRKCA|PRKCB|PRKCD|PRKCE|PRKCH|PRKCQ | PKC inhibitor | Details | |
| C05024 | BRD-K71900389 | SP-100030 | JUN|NFKB1 | NFkB pathway inhibitor | Details | |
| C05025 | BRD-K28571773 | SP-141 | MDM2 | ubiquitin ligase inhibitor | Details | |
| C05026 | BRD-K23005288 | SP-420 | Details | |||
| C05027 | BRD-K68405354 | spaglumic-acid | GRM3 | glutamate receptor antagonist | Details | |
| C05028 | BRD-K07612980 | sparfloxacin | TOP2A | bacterial DNA gyrase inhibitor | Details | |
| C05029 | BRD-A81539525 | sparfosate | CA2|CA4|CAD | aspartate carbamoyltransferase inhibitor | Details | |
| C05030 | BRD-K32847234 | sparteine-sulfate | Details | |||
| C05031 | BRD-K84964099 | spautin-1 | USP10|USP13 | deubiquitinase inhibitor | Details | |
| C05032 | BRD-K11905747 | spectinomycin | bacterial 30S ribosomal subunit inhibitor | Details | ||
| C05033 | BRD-K40438880 | spermidine | KCNJ4|TXNRD1 | glutamate receptor modulator | Details | |
| C05034 | BRD-K18375018 | spermine | CA14|CA4|CA6|CA9|CASR|GRIN1|GRIN2A|KCNJ4|ODC1|SMOX|SMS|TRPM4|TRPM5 | Details | ||
| C05035 | BRD-A35379661 | sphingosylphosphorylcholine | GPR12 | gene expression stimulant | Details | |
| C05036 | BRD-K55468218 | spiperone | ADRA1A|ADRA1B|ADRA1D|DRD1|DRD2|DRD3|DRD4|DRD5|HTR1A|HTR1D|HTR2A|HTR2B|HTR2C|HTR6|HTR7 | dopamine receptor antagonist | Details | |
| C05037 | BRD-K28192623 | spiradoline | OPRK1 | opioid receptor agonist | Details | |
| C05038 | BRD-A67305656 | spiramycin | bacterial 50S ribosomal subunit inhibitor | Details | ||
| C05039 | BRD-K96684644 | spirobromin | Details | |||
| C05040 | BRD-K90027355 | spironolactone | AR|CACNA1A|CACNA1B|CACNA1C|CACNA1D|CACNA1F|CACNA1G|CACNA1H|CACNA1I|CACNA1S|CACNA2D1|CACNA2D2|CACNA2D3|CACNB1|CACNB2|CACNB3|CACNB4|CACNG1|CYP11B2|NR3C1|NR3C2|PGR|SHBG | mineralocorticoid receptor antagonist | Details | |
| C05041 | BRD-A72483914 | spiroxatrine | ADRA1A|ADRA1B|ADRA1D|ADRA2A|ADRA2B|ADRA2C|HTR1A|HTR2B | serotonin receptor antagonist | Details | |
| C05042 | BRD-K94934625 | spizofurone | Details | |||
| C05043 | BRD-K27710560 | splitomycin | SIRT1 | SIRT inhibitor | Details | |
| C05044 | BRD-K63253858 | SPP-86 | RET | receptor tyrosine protein kinase inhibitor | Details | |
| C05045 | BRD-K19203487 | SPP301 | EDNRA | endothelin receptor antagonist | Details | |
| C05046 | BRD-A08772153 | SQ-109 | FDFT1 | bacterial cell wall synthesis inhibitor | Details | |
| C05047 | BRD-A56987319 | SQ-22536 | ADCY1 | adenylyl cyclase inhibitor | Details | |
| C05048 | BRD-K26501486 | SR-1078 | RORA|RORC | retinoid receptor agonist | Details | |
| C05049 | BRD-K16229414 | SR-11302 | Details | |||
| C05050 | BRD-K60931454 | SR-140333 | TACR1 | neurokinin receptor antagonist | Details | |
| C05051 | BRD-K62814487 | SR-1664 | PPARG | PPAR receptor ligand | Details | |
| C05052 | BRD-K11641193 | SR-2211 | RORC | retinoid receptor inverse agonist | Details | |
| C05053 | BRD-K62562723 | SR-2640 | CYSLTR1 | leukotriene receptor antagonist | Details | |
| C05054 | BRD-K35629949 | SR-27897 | CCKAR | CCK receptor antagonist | Details | |
| C05055 | BRD-K60952143 | SR-3306 | MAPK10|MAPK8|MAPK9 | JNK inhibitor | Details | |
| C05056 | BRD-K43002771 | SR-33805 | calcium channel blocker | Details | ||
| C05057 | BRD-K50378376 | SR-3576 | MAPK10 | JNK inhibitor | Details | |
| C05058 | BRD-A86468475 | SR-3677 | ROCK2 | rho associated kinase inhibitor | Details | |
| C05059 | BRD-K09397065 | SR-57227A | HTR3A | serotonin receptor agonist | Details | |
| C05060 | BRD-K35430135 | SR-59230A | ADRB1|ADRB2|ADRB3 | adrenergic receptor antagonist | Details | |
| C05061 | BRD-K19309090 | SR-95639A | CHRM1 | acetylcholine receptor agonist | Details | |
| C05062 | BRD-K50495309 | SRC-kinase-inhibitor-I | CSK|LCK|RIPK2 | src inhibitor | Details | |
| C05063 | BRD-K62621335 | SRPIN340 | SRPK1|SRPK2 | serine arginine protein kinase inhibitor | Details | |
| C05064 | BRD-K95926480 | SRT1720 | SIRT1 | SIRT activator | Details | |
| C05065 | BRD-K48452630 | SRT2104 | SIRT1 | SIRT activator | Details | |
| C05066 | BRD-K02782351 | SSR-180711 | CHRNA7 | acetylcholine receptor agonist | Details | |
| C05067 | BRD-K65890018 | SSR128129E | Details | |||
| C05068 | BRD-K73524797 | ST-1859 | antiamyloidogenic agent | Details | ||
| C05069 | BRD-K68470841 | ST-2825 | MYD88 | myeloid differentiation primary response inhibitor | Details | |
| C05070 | BRD-K18905250 | ST-91 | adrenergic receptor agonist | Details | ||
| C05071 | BRD-K41783120 | STA-5326 | IL12A | interleukin synthesis inhibitor | Details | |
| C05072 | BRD-K46791647 | stanozolol | AR | androgen receptor agonist | Details | |
| C05073 | BRD-K17061841 | stattic | Details | |||
| C05074 | BRD-K40853697 | STAT3-inhibitor-VI | STAT3 | STAT inhibitor | Details | |
| C05075 | BRD-K93880783 | stavudine | DNA directed DNA polymerase inhibitor; nucleoside reverse transcriptase inhibitor | Details | ||
| C05076 | BRD-K36739687 | stemregenin-1 | AHR | aryl hydrocarbon receptor antagonist | Details | |
| C05077 | BRD-A04506385 | stepronin | mucolytic agent | Details | ||
| C05078 | BRD-K93900986 | stetaderm | Details | |||
| C05079 | BRD-K13049524 | STF-083010 | ERN1 | serine/threonine kinase inhibitor | Details | |
| C05080 | BRD-K39171998 | STF-118804 | NAMPT | NAMPT inhibitor | Details | |
| C05081 | BRD-K22477529 | STF-31 | NAMPT|SLC2A1 | NAMPT inhibitor | Details | |
| C05082 | BRD-K85479953 | STF-62247 | autophagy inducer | Details | ||
| C05083 | BRD-K41422683 | stigmasterol | Details | |||
| C05084 | BRD-A72441487 | stiripentol | GABRA3 | GABA uptake inhibitor | Details | |
| C05085 | BRD-A85069489 | stobadine | ADRA1A | adrenergic receptor antagonist | Details | |
| C05086 | BRD-K07166362 | streptomycin | bacterial 30S ribosomal subunit inhibitor | Details | ||
| C05087 | BRD-K34411947 | streptozotocin | SLC2A2 | DNA alkylating agent | Details | |
| C05088 | BRD-K83146339 | strontium-ranelate | CASR | bone formation stimulant; bone resorption inhibitor | Details | |
| C05089 | BRD-A09094913 | strychnine | CHRM1|CHRM2|CHRM3|CHRM4|CHRM5|CHRNA10|CHRNA9|GLRA1|GLRA2|GLRA3|GLRB | acetylcholine receptor antagonist | Details | |
| C05090 | BRD-K02965346 | SU-11274 | MET | hepatocyte growth factor receptor inhibitor; tyrosine kinase inhibitor | Details | |
| C05091 | BRD-K91106808 | SU-16f | PDGFRB | PDGFR tyrosine kinase receptor inhibitor | Details | |
| C05092 | BRD-K20287671 | SU-4312 | KDR|PDGFRB | PDGFR tyrosine kinase receptor inhibitor; tyrosine kinase inhibitor; VEGFR inhibitor | Details | |
| C05093 | BRD-K23106423 | substance-p | TACR1|TACR2|TACR3 | neurokinin receptor antagonist | Details | |
| C05094 | BRD-K45238818 | succinic-acid | ALDH5A1|ASPH|BBOX1|HSD17B6|OXCT1|OXCT2|P3H1|P3H2|P3H3|P4HA1|P4HA2|PLOD1|PLOD3|SDHA|SDHB|SDHC|SDHD|SLC13A1|SLC13A2|SLC13A3|SLC25A10|SUCLA2|SUCLG1|SUCLG2|SUCNR1|TMLHE | Details | ||
| C05095 | BRD-K45497762 | succinylcholine-chloride | CHRFAM7A|CHRM1|CHRM2|CHRM3|CHRNA1|CHRNA10 | Details | ||
| C05096 | BRD-K01950558 | succinylsulfathiazole | DHFR | dihydrofolate reductase inhibitor | Details | |
| C05097 | BRD-M71167108 | sucralfate | EGF|FGA|FGB|FGF2|FGG | antacid | Details | |
| C05098 | BRD-K58968598 | sucralose | Details | |||
| C05099 | BRD-K74724920 | sucrose | ACTA1|ATOX1|C22orf28|LYZ | Details | ||
| C05100 | BRD-K01294196 | sucrose-octaacetate | Details |