CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C05501 | BRD-K26420709 | toyocamycin | ERN1 | serine/threonine kinase inhibitor | Details | |
| C05502 | BRD-K93045741 | tozadenant | ADORA2A | adenosine receptor antagonist | Details | |
| C05503 | BRD-K59369769 | tozasertib | AURKA|AURKB|AURKC|LCK | Aurora kinase inhibitor; Bcr-Abl kinase inhibitor; FLT3 inhibitor; JAK inhibitor | Details | |
| C05504 | BRD-K87941707 | TP-003 | GABRA1|GABRA2|GABRA3|GABRA5 | GABA receptor inverse agonist | Details | |
| C05505 | BRD-K84034737 | TP-0903 | AXL | AXL kinase inhibitor | Details | |
| C05506 | BRD-K51575138 | TPCA-1 | IKBKB | IKK inhibitor | Details | |
| C05507 | BRD-K39805756 | TPPS4 | Details | |||
| C05508 | BRD-K34154330 | tracazolate | GABRA1 | GABA receptor modulator | Details | |
| C05509 | BRD-K30071764 | TRAM-34 | KCNN4 | potassium channel antagonist | Details | |
| C05510 | BRD-K81341251 | TRAM-39 | KCNN4 | calcium-activated potassium channel activator | Details | |
| C05511 | BRD-K51033547 | tramadol | CHRFAM7A|CHRM3|GRIN3A|HTR2C|OPRD1|OPRK1|OPRM1|SLC6A2|SLC6A4 | norepinephrine reputake inhibitor; opioid receptor agonist; serotonin reuptake inhibitor | Details | |
| C05512 | BRD-K12343256 | trametinib | MAP2K1|MAP2K2 | MEK inhibitor | Details | |
| C05513 | BRD-K82234479 | tramiprosate | APP | beta amyloid protein neurotoxicity inhibitor | Details | |
| C05514 | BRD-A32505112 | trandolapril | ACE | angiotensin converting enzyme inhibitor | Details | |
| C05515 | BRD-K15014948 | tranexamic-acid | PLG | antifibrinolytic; plasminogen activator inhibitor | Details | |
| C05516 | BRD-K17849083 | tranilast | HPGDS|HRH1 | angiogenesis inhibitor | Details | |
| C05517 | BRD-K26222048 | trans-10,cis-12-Conjugated-linoleic-acid | Details | |||
| C05518 | BRD-K42959922 | trans-2-Undecenoic-acid | Details | |||
| C05519 | BRD-K75080769 | trans-4-[8-(3-Fluorophenyl)-1,7-naphthyridin-6-yl]cyclohexanecarboxylic-acid | Details | |||
| C05520 | BRD-K91614056 | trans-4-Hydroxycrotonic-acid | gamma hydroxybutyric acid ligand | Details | ||
| C05521 | BRD-K26273521 | trans-4-Methoxycinnamic-acid | Details | |||
| C05522 | BRD-K88809146 | tranylcypromine | KDM1A|MAOA|MAOB | monoamine oxidase inhibitor | Details | |
| C05523 | BRD-K69837166 | trap-101 | OPRL1 | nociceptin/orphanin FQ receptor antagonist; opioid receptor antagonist | Details | |
| C05524 | BRD-K95763993 | trapidil | PDGFRA | PDGFR tyrosine kinase receptor inhibitor | Details | |
| C05525 | BRD-K23976833 | travoprost | PTGFR | prostanoid receptor agonist | Details | |
| C05526 | BRD-K38158531 | traxoprodil | GRIN2B | glutamate receptor antagonist | Details | |
| C05527 | BRD-K70778732 | trazodone | ADRA1A|ADRA2A|HRH1|HTR1A|HTR2A|HTR2B|HTR2C|SLC6A4 | adrenergic receptor antagonist; serotonin receptor antagonist; serotonin reuptake inhibitor | Details | |
| C05528 | BRD-A20686268 | trebenzomine | Details | |||
| C05529 | BRD-A88369366 | trelagliptin | DPP4 | dipeptidyl peptidase inhibitor | Details | |
| C05530 | BRD-K08619838 | tremorine | acetylcholine receptor agonist | Details | ||
| C05531 | BRD-K20902145 | treosulfan | DNA synthesis inhibitor | Details | ||
| C05532 | BRD-K37543758 | trepibutone | CHRM1|CHRM2|CHRM3|CHRM4 | cholinergic receptor antagonist | Details | |
| C05533 | BRD-K84663978 | trequinsin | PDE5A | phosphodiesterase inhibitor | Details | |
| C05534 | BRD-K08748705 | tretazicar | NQO2 | DNA replication inhibitor | Details | |
| C05535 | BRD-K71879491 | tretinoin | ALDH1A1|ALDH1A2|GPRC5A|NR0B1|NR2C2|PPARD|RARA|RARB|RARG|RARRES1|RORB|RORC|RXRB|RXRG | retinoid receptor agonist; retinoid receptor ligand | Details | |
| C05536 | BRD-K92844263 | triacetin | Details | |||
| C05537 | BRD-K77554836 | triamcinolone | NR3C1|SERPINA6 | glucocorticoid receptor agonist | Details | |
| C05538 | BRD-A92439610 | triamcinolone-acetonide | NR3C1 | glucocorticoid receptor agonist; immunosuppressant | Details | |
| C05539 | BRD-K92049597 | triamterene | SCNN1A|SCNN1B|SCNN1D|SCNN1G | sodium channel blocker | Details | |
| C05540 | BRD-K01669786 | triapine | RRM1|RRM2 | ribonucleotide reductase inhibitor | Details | |
| C05541 | BRD-K76890464 | triazolam | GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRB1|GABRB2|GABRB3|GABRD|GABRE|GABRG1|GABRG2|GABRG3|GABRP|GABRQ|GABRR1|GABRR2|GABRR3|TSPO | GABA benzodiazepine site receptor agonist | Details | |
| C05542 | BRD-A60294240 | tribenoside | anti-inflammatory agent; capillary stabilizing agent | Details | ||
| C05543 | BRD-K09118247 | tribomsalan | Details | |||
| C05544 | BRD-K69632891 | tribromoethanol | analgesic agent | Details | ||
| C05545 | BRD-K38969488 | tributyrin | HDAC inhibitor | Details | ||
| C05546 | BRD-K24790130 | tricaprylin | Details | |||
| C05547 | BRD-A28940325 | trichlormethiazide | ATP1A1|CA1|CA2|CA4|SLC12A1|SLC12A3 | chloride channel blocker | Details | |
| C05548 | BRD-K29888499 | trichlormethine | DNA alkylating agent | Details | ||
| C05549 | BRD-K42090719 | trichloroacetic-acid | Details | |||
| C05550 | BRD-K46435528 | trichloroethylene | Details | |||
| C05551 | BRD-K68202742 | trichostatin-a | HDAC1|HDAC10|HDAC2|HDAC3|HDAC4|HDAC5|HDAC6|HDAC7|HDAC8|HDAC9 | HDAC inhibitor | Details | |
| C05552 | BRD-K80431395 | triciribine | AKT1|AKT2|AKT3 | AKT inhibitor | Details | |
| C05553 | BRD-K81916719 | triclabendazole | DNMT1 | microtubule inhibitor | Details | |
| C05554 | BRD-K25029121 | triclocarban | other antibiotic | Details | ||
| C05555 | BRD-K41731458 | triclosan | DNMT1 | antibacterial agent | Details | |
| C05556 | BRD-A22152765 | tridihexethyl | CHRM1|CHRM2|CHRM3 | acetylcholine receptor antagonist | Details | |
| C05557 | BRD-K37111771 | trientine | CA14 | chelating agent | Details | |
| C05558 | BRD-K89732114 | trifluoperazine | ADRA1A|CALM1|CALY|DRD2|DRD4|HRH1|HTR2A|HTR2C|S100A4|TNNC1 | dopamine receptor antagonist | Details | |
| C05559 | BRD-K63675182 | triflupromazine | CHRM1|CHRM2|DRD1|DRD2|HTR2B | dopamine receptor antagonist | Details | |
| C05560 | BRD-K03243820 | trifluridine | TYMS | DNA directed DNA polymerase inhibitor; thymidylate synthase inhibitor | Details | |
| C05561 | BRD-K71696703 | triflusal | NFKB1|NOS2|PDE10A|PTGS1 | cyclooxygenase inhibitor; platelet aggregation inhibitor; thromboxane synthase inhibitor | Details | |
| C05562 | BRD-K69231085 | trigonelline | Details | |||
| C05563 | BRD-A48180038 | trihexyphenidyl | CHRM1|CHRM2|CHRM3|CHRM4|CHRM5 | acetylcholine receptor antagonist | Details | |
| C05564 | BRD-A04497688 | trilostane | ESR1|ESR2|HSD3B1|HSD3B2 | 3beta-hydroxy-delta5-steroid dehydrogenase inhibitor | Details | |
| C05565 | BRD-K36851334 | TRIM | Details | |||
| C05566 | BRD-A92630576 | trimebutine | OPRD1|OPRK1|OPRM1 | opioid receptor agonist | Details | |
| C05567 | BRD-M58473998 | trimeprazine | HRH1 | histamine receptor ligand; histamine receptor antagonist | Details | |
| C05568 | BRD-K88366685 | trimetazidine | ACAA2 | 3-ketoacyl CoA thiolase inhibitor | Details | |
| C05569 | BRD-K16606819 | trimethadione | CACNA1G|CACNA1H|CACNA1I | oxazolidine antiepileptic | Details | |
| C05570 | BRD-K34415467 | trimethobenzamide | DRD2 | histamine receptor antagonist | Details | |
| C05571 | BRD-K07208025 | trimethoprim | DHFR|TYMS | dihydrofolate reductase inhibitor | Details | |
| C05572 | BRD-A56241705 | trimethoquinol | ADRB2|ADRB3 | adrenergic receptor antagonist | Details | |
| C05573 | BRD-K24483849 | trimethylolpropane-triacrylate | Details | |||
| C05574 | BRD-K53220666 | trimetozine | sedative | Details | ||
| C05575 | BRD-A19195498 | trimipramine | ADRA1A|ADRA1B|ADRA2A|ADRA2B|ADRB1|ADRB2|ADRB3|CHRM1|CHRM2|CHRM3|CHRM4|CHRM5|DRD1|DRD2|DRD5|HRH1|HTR1A|HTR1D|HTR2A|HTR2C|HTR3A|SLC6A2|SLC6A3|SLC6A4 | norepinephrine reputake inhibitor; tricyclic antidepressant | Details | |
| C05576 | BRD-K54790157 | trioxsalen | DNA synthesis inhibitor | Details | ||
| C05577 | BRD-K57033106 | tripelennamine | HRH1 | histamine receptor antagonist | Details | |
| C05578 | BRD-K11742128 | triprolidine | HRH1 | histamine receptor antagonist | Details | |
| C05579 | BRD-K19427720 | triptan | HTR1B|HTR1D | serotonin receptor agonist | Details | |
| C05580 | BRD-K39484304 | triptolide | RELA | RNA polymerase inhibitor | Details | |
| C05581 | BRD-K62685538 | triptorelin | GNRHR | gonadotropin releasing factor hormone receptor agonist | Details | |
| C05582 | BRD-K76375510 | troclosene | Details | |||
| C05583 | BRD-K83502127 | trofinetide | IFNG|IL6|TNF | cytokine production inhibitor | Details | |
| C05584 | BRD-A13084692 | troglitazone | ACSL4|ESRRA|ESRRG|PPARG|SERPINE1|SLC29A1|TRPM3 | insulin sensitizer; PPAR receptor agonist | Details | |
| C05585 | BRD-A24297246 | troleandomycin | protein synthesis inhibitor | Details | ||
| C05586 | BRD-A17846016 | trolox | antioxidant | Details | ||
| C05587 | BRD-K91422571 | tromaril | prostanoid receptor antagonist | Details | ||
| C05588 | BRD-K47978074 | trometamol | AMD1|CANT1|DCN|NEIL1|VEGFA | Details | ||
| C05589 | BRD-A84389633 | tropanyl-3,5-dimethylbenzoate | HTR3A|HTR3B | serotonin receptor antagonist | Details | |
| C05590 | BRD-A34603619 | tropesin | PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C05591 | BRD-A79672927 | tropicamide | CHRM1|CHRM2|CHRM3|CHRM4 | acetylcholine receptor antagonist | Details | |
| C05592 | BRD-K50866992 | tropisetron | GLRA1|GLRA2|GLRB|HTR3A|HTR4 | serotonin receptor antagonist | Details | |
| C05593 | BRD-K69469734 | trospium | CHRM1 | acetylcholine receptor antagonist | Details | |
| C05594 | BRD-K00494077 | trovafloxacin | TOP2A | bacterial DNA gyrase inhibitor | Details | |
| C05595 | BRD-A35868371 | troventol | Details | |||
| C05596 | BRD-K00989047 | trovirdine | non-nucleoside reverse transcriptase inhibitor | Details | ||
| C05597 | BRD-K73529671 | troxerutin | antioxidant | Details | ||
| C05598 | BRD-A68589262 | troxipide | glucosamine synthetase stimulant | Details | ||
| C05599 | BRD-K35626314 | TRV130 | OPRM1 | opioid receptor agonist | Details | |
| C05600 | BRD-K76973696 | tryptanthrin | IDO1 | cyclooxygenase inhibitor | Details |