CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C00901 | BRD-A05186015 | bupropion | CHRNA3|SLC6A2|SLC6A3 | dopamine uptake inhibitor | Details | |
| C00902 | BRD-K30360804 | buramate | antiepileptic | Details | ||
| C00903 | BRD-K93461745 | buspirone | DRD2|HTR1A | serotonin receptor agonist | Details | |
| C00904 | BRD-K23204545 | busulfan | DNA inhibitor | Details | ||
| C00905 | BRD-K40581315 | butabindide | TPP2 | tripeptidyl peptidase inhibitor | Details | |
| C00906 | BRD-K99622919 | butacaine | local anesthetic | Details | ||
| C00907 | BRD-K23082237 | butaclamol | DRD1|DRD2|DRD3|DRD4|DRD5|HTR1A|HTR2A | dopamine receptor antagonist | Details | |
| C00908 | BRD-K71350836 | butalbital | CHRNA4|CHRNA7|GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRB1|GABRB2|GABRB3|GABRD|GABRE|GABRG1|GABRG2|GABRG3|GABRP|GABRQ|GRIA2|GRIK2 | GABA receptor antagonist | Details | |
| C00909 | BRD-K27217864 | butamben | sodium channel blocker | Details | ||
| C00910 | BRD-K17497770 | butein | ACE | EGFR inhibitor; src inhibitor | Details | |
| C00911 | BRD-K90630139 | butenafine | SQLE | fungal squalene epoxidase inhibitor | Details | |
| C00912 | BRD-A47706533 | buthionine-sulfoximine | GCLM | glutathione transferase inhibitor | Details | |
| C00913 | BRD-A46136514 | butibufen | cyclooxygenase inhibitor | Details | ||
| C00914 | BRD-A16665823 | butoconazole | bacterial cell wall synthesis inhibitor | Details | ||
| C00915 | BRD-A27274504 | butofilolol | adrenergic receptor antagonist | Details | ||
| C00916 | BRD-K42417338 | butorphanol-(+)-tartrate | OPRD1|OPRK1|OPRM1 | opioid receptor agonist; opioid receptor antagonist | Details | |
| C00917 | BRD-K08287586 | butyl-paraben | DNA synthesis inhibitor | Details | ||
| C00918 | BRD-K93035859 | butylated-hydroxyanisole | antioxidant | Details | ||
| C00919 | BRD-K53153417 | butylated-hydroxytoluene | CA2 | carbonic anhydrase inhibitor | Details | |
| C00920 | BRD-A59378440 | butylphthalide | KCNK2 | potassium channel antagonist | Details | |
| C00921 | BRD-A53951045 | butylscopolamine-bromide | cholinergic receptor antagonist | Details | ||
| C00922 | BRD-K56115039 | BU226 | imidazoline receptor ligand | Details | ||
| C00923 | BRD-K28965160 | BVD-523 | MAP kinase inhibitor | Details | ||
| C00924 | BRD-K01742705 | BVT-2733 | HSD17B1 | 11-beta hydroxysteroid dehydrogenase inhibitor | Details | |
| C00925 | BRD-K68567222 | BVT-948 | PTPN1|PTPN11|PTPN2 | tyrosine phosphatase inhibitor | Details | |
| C00926 | BRD-K80194255 | BW-A4C | ALOX5 | lipoxygenase inhibitor | Details | |
| C00927 | BRD-A55946879 | BW-B70C | ALOX5 | lipoxygenase inhibitor | Details | |
| C00928 | BRD-K57927309 | BW-180C | OPRD1|OPRM1 | opioid receptor agonist | Details | |
| C00929 | BRD-K74990253 | BW-373U86 | OPRD1 | opioid receptor agonist | Details | |
| C00930 | BRD-K07061232 | BW-616U | MAOA | monoamine oxidase inhibitor | Details | |
| C00931 | BRD-A17428743 | BW-723C86 | HTR2A|HTR2B|HTR2C | serotonin receptor agonist | Details | |
| C00932 | BRD-K47983010 | BX-795 | CDK2|CHEK1|GSK3B|KDR|PDK1|PDPK1 | IKK inhibitor | Details | |
| C00933 | BRD-K49669041 | BX-912 | CDK2|CHEK1|GSK3B|KDR|PDK1|PDPK1 | pyruvate dehydrogenase kinase inhibitor | Details | |
| C00934 | BRD-K61665160 | BYK-204165 | PARP1 | PARP inhibitor | Details | |
| C00935 | BRD-K98179423 | C-021 | CCR4 | CC chemokine receptor antagonist | Details | |
| C00936 | BRD-K72462751 | C-1 | PRKCA | protein kinase inhibitor | Details | |
| C00937 | BRD-K15337272 | C-751 | Details | |||
| C00938 | BRD-K41504985 | cabagin | Details | |||
| C00939 | BRD-K54028654 | cabaletta | pharmacological chaperone | Details | ||
| C00940 | BRD-K06858286 | cabazitaxel | TUBA4A|TUBB|TUBB1 | microtubule inhibitor | Details | |
| C00941 | BRD-K86882815 | cabergoline | ADRA1A|ADRA1B|ADRA1D|ADRA2A|ADRA2B|ADRA2C|ADRB1|ADRB2|DRD1|DRD2|DRD3|DRD4|DRD5|HTR1A|HTR1B|HTR1D|HTR2A|HTR2B|HTR2C|HTR7 | dopamine receptor agonist | Details | |
| C00942 | BRD-K76819217 | cabotegravir | HIV integrase inhibitor | Details | ||
| C00943 | BRD-K51544265 | cabozantinib | KDR|MET | RET tyrosine kinase inhibitor; VEGFR inhibitor | Details | |
| C00944 | BRD-A90751343 | CaCCinh-A01 | CLCA1 | calcium-activated chloride channel inhibitor | Details | |
| C00945 | BRD-A78134170 | cadralazine | adrenergic receptor antagonist | Details | ||
| C00946 | BRD-K46741531 | cafestol | pregnane X receptor agonist | Details | ||
| C00947 | BRD-K09900591 | caffeic-acid | ALOX5|MIF | HIV integrase inhibitor; lipoxygenase inhibitor; nitric oxide production inhibitor; tumor necrosis factor production inhibitor | Details | |
| C00948 | BRD-K96188950 | caffeic-acid-phenethyl-ester | RELA | HIV integrase inhibitor | Details | |
| C00949 | BRD-K02404261 | caffeine | ADORA1|ADORA2A|ADORA2B|ADORA3|ATM|ITPR1|ITPR2|ITPR3|PDE10A|PDE11A|PDE1A|PDE1B|PDE1C|PDE2A|PDE3A|PDE3B|PDE4A|PDE4B|PDE4C|PDE4D|PDE5A|PDE6A|PDE6B|PDE6C|PDE7A|PDE7B|PDE8A|PDE8B|PDE9A|PIK3CA|PIK3CB|PIK3CD|PRKDC|RYR1|RYR2|RYR3 | adenosine receptor antagonist; phosphodiesterase inhibitor | Details | |
| C00950 | BRD-K77175907 | calcifediol | VDR | vitamin D receptor agonist | Details | |
| C00951 | BRD-K56429665 | calcipotriol | VDR | vitamin D receptor agonist | Details | |
| C00952 | BRD-K27316855 | calcitriol | VDR | vitamin D receptor agonist | Details | |
| C00953 | BRD-K35952844 | calcium-gluceptate | Details | |||
| C00954 | BRD-K97009491 | calcium-levofolinate | Details | |||
| C00955 | BRD-K19811997 | Calhex-231 | CASR | calcium sensing receptor negative allosteric modulator | Details | |
| C00956 | BRD-K26134695 | calpeptin | calpain inhibitor | Details | ||
| C00957 | BRD-K23248433 | camicinal | MLNR | motilin receptor agonist | Details | |
| C00958 | BRD-K35772771 | CaMKII-IN-1 | AKT1|CAMK2A|CAMK4|MYLK | calcium/calmodulin dependent protein kinase inhibitor | Details | |
| C00959 | BRD-K43806473 | camostat-mesilate | PRSS1 | protease inhibitor | Details | |
| C00960 | BRD-K10034334 | camphor-(+) | TRPV1 | Details | ||
| C00961 | BRD-K15714472 | camphor-(1r) | TRPV activator | Details | ||
| C00962 | BRD-K37890730 | camptothecin | TOP1 | topoisomerase inhibitor | Details | |
| C00963 | BRD-A91733352 | camylofine-chlorhydrate | Details | |||
| C00964 | BRD-K90868879 | canagliflozin | SLC5A1|SLC5A2 | sodium/glucose cotransporter inhibitor | Details | |
| C00965 | BRD-K84091759 | candesartan | AGTR1 | angiotensin receptor antagonist | Details | |
| C00966 | BRD-A65671304 | candesartan-cilextil | AGTR1|AGTR2 | angiotensin receptor antagonist | Details | |
| C00967 | BRD-A37348498 | candicidin | fungal ergosterol inhibitor | Details | ||
| C00968 | BRD-K50168500 | canertinib | AKT1|EGFR|ERBB2|ERBB4 | EGFR inhibitor | Details | |
| C00969 | BRD-A20644369 | canrenone | NR3C2 | mineralocorticoid receptor antagonist | Details | |
| C00970 | BRD-K80684056 | cantharidin | protein phosphatase inhibitor | Details | ||
| C00971 | BRD-K97025174 | capadenoson | ADORA1 | adenosine receptor agonist | Details | |
| C00972 | BRD-K61192372 | capecitabine | TYMS | DNA synthesis inhibitor; thymidylate synthase inhibitor | Details | |
| C00973 | BRD-K04282412 | capobenic-acid | Details | |||
| C00974 | BRD-A33801468 | capreomycin | protein synthesis inhibitor | Details | ||
| C00975 | BRD-K35170555 | caprylic-acid | Details | |||
| C00976 | BRD-K50590187 | capsaicin | CFTR|TRPV1 | TRPV agonist | Details | |
| C00977 | BRD-K44849676 | capsazepine | TRPV1|TRPV4 | TRPV agonist | Details | |
| C00978 | BRD-K81645907 | captamine | Details | |||
| C00979 | BRD-A79857384 | captan | Details | |||
| C00980 | BRD-K54529596 | captopril | ACE|LTA4H|MMP2|MMP9 | angiotensin converting enzyme inhibitor | Details | |
| C00981 | BRD-K62790656 | caracemide | RRM1 | ribonucleotide reductase inhibitor | Details | |
| C00982 | BRD-K59895502 | caramiphen | CHRM1|CHRM2 | cholinergic receptor antagonist | Details | |
| C00983 | BRD-A50675490 | carazolol | ADRB1|ADRB2|ADRB3 | adrenergic receptor antagonist | Details | |
| C00984 | BRD-K75037734 | carbachol | CHRM1|CHRM2|CHRM3|CHRM4|CHRM5|CHRNA2 | cholinergic receptor agonist | Details | |
| C00985 | BRD-K56735750 | carbadox | other antibiotic | Details | ||
| C00986 | BRD-K71799949 | carbamazepine | SCN10A|SCN11A|SCN1A|SCN2A|SCN3A|SCN4A|SCN5A|SCN7A|SCN8A|SCN9A | carboxamide antiepileptic | Details | |
| C00987 | BRD-K54208592 | carbaril | acetylcholinesterase inhibitor | Details | ||
| C00988 | BRD-K94848716 | carbarsone | antiprotozoal agent | Details | ||
| C00989 | BRD-A11070335 | carbazochrome | Details | |||
| C00990 | BRD-K12906202 | carbendazim | TP53|TUBB | microtubule inhibitor; tubulin polymerization inhibitor | Details | |
| C00991 | BRD-A13078313 | carbenicillin | bacterial cell wall synthesis inhibitor | Details | ||
| C00992 | BRD-A29700858 | carbenoxolone | GJA1|GJA10|GJA3|GJA4|GJA5|GJA8|GJA9|GJB1|GJB2|GJB3|GJB4|GJB5|GJB6|GJB7|GJC1|GJC2|GJC3|GJD2|GJD3|GJD4|GJE1|HSD11B1|PANX1|PANX2|PANX3 | 11-beta hydroxysteroid dehydrogenase inhibitor | Details | |
| C00993 | BRD-K06181161 | carbetapentane | CHRM2 | acetylcholine receptor antagonist | Details | |
| C00994 | BRD-K56107812 | carbetocin | OXTR | oxytocin receptor agonist | Details | |
| C00995 | BRD-K78712176 | carbidopa | DDC | aromatic L-amino acid decarboxylase inhibitor | Details | |
| C00996 | BRD-K87156652 | carbimazole | TPO | antithyroid agent | Details | |
| C00997 | BRD-A29426959 | carbinoxamine | HRH1 | histamine receptor antagonist | Details | |
| C00998 | BRD-K90947825 | carboplatin | DNA alkylating agent; DNA inhibitor | Details | ||
| C00999 | BRD-K68408772 | carboxyamidotriazole | CXCL8 | calcium channel blocker | Details | |
| C01000 | BRD-K23533833 | carboxylosartan | AGTR1 | angiotensin antagonist | Details |