CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C02001 | BRD-K66766661 | estradiol-valerate | ESR1 | estrogen receptor agonist | Details | |
| C02002 | BRD-A70858459 | estramustine | ESR1|ESR2|MAP1A|MAP2 | DNA alkylating agent | Details | |
| C02003 | BRD-K00077635 | estramustine-phosphate | ESR1|ESR2|MAP1A|MAP2 | DNA synthesis inhibitor; microtubule inhibitor | Details | |
| C02004 | BRD-K17016787 | estriol | ESR1|ESR2 | estrogen receptor agonist | Details | |
| C02005 | BRD-K81839095 | estrone | ESR1|ESR2 | estrogen receptor agonist; estrogenic hormone | Details | |
| C02006 | BRD-A22143024 | estropipate | ESR1|ESR2 | estrogen receptor agonist | Details | |
| C02007 | BRD-K29220403 | eszopiclone | GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRB1|GABRB2|GABRB3|GABRD|GABRE|GABRG1|GABRG2|GABRG3|GABRP|GABRQ|TSPO | benzodiazepine receptor agonist | Details | |
| C02008 | BRD-K63630713 | etacrynic-acid | ATP1A1|SLC12A1 | sodium/potassium/chloride transporter inhibitor | Details | |
| C02009 | BRD-K84971356 | etafenone | calcium channel blocker | Details | ||
| C02010 | BRD-K71055333 | etamsylate | haemostatic agent | Details | ||
| C02011 | BRD-K96042922 | etanidazole | bacterial cell wall synthesis inhibitor | Details | ||
| C02012 | BRD-K64755930 | etazolate | GABRB3|PDE4A | phosphodiesterase inhibitor | Details | |
| C02013 | BRD-K63177377 | ETC-1002 | ACLY | AMPK inhibitor | Details | |
| C02014 | BRD-K54264768 | ETC-159 | PORCN | porcupine inhibitor; beta catenin inhibitor | Details | |
| C02015 | BRD-K24443618 | etebenecid | uricosuric blocker | Details | ||
| C02016 | BRD-K64834129 | eterobarb | anticonvulsant | Details | ||
| C02017 | BRD-K10667240 | ethacizin | anticonvulsant | Details | ||
| C02018 | BRD-K24715592 | ethacridine-lactate-monohydrate | DNA intercalating agent | Details | ||
| C02019 | BRD-K93231391 | ethambutol | bacterial cell wall synthesis inhibitor | Details | ||
| C02020 | BRD-K38055836 | ethamivan | respiratory stimulant | Details | ||
| C02021 | BRD-M75061779 | ethanolamine-oleate | F12|FABP4|FFAR1|FFAR4|PLD2 | immunostimulant | Details | |
| C02022 | BRD-K36756879 | ethaverine | calcium channel blocker | Details | ||
| C02023 | BRD-K88308881 | ethenzamide | analgesic agent | Details | ||
| C02024 | BRD-K19672466 | ethimizol | Details | |||
| C02025 | BRD-K48195008 | ethinyl-estradiol | ESR1|ESR2|NR1I2 | estrogen receptor agonist; estrogenic hormone | Details | |
| C02026 | BRD-K51207550 | ethionamide | mycolic synthesis inhibitor | Details | ||
| C02027 | BRD-A29111201 | ethisterone | TYR | progestogen hormone | Details | |
| C02028 | BRD-K02475039 | ethopabate | antiprotozoal agent | Details | ||
| C02029 | BRD-A99633051 | ethosuximide | CACNA1G|CACNA1H|CACNA1I | succinimide antiepileptic | Details | |
| C02030 | BRD-A30205217 | ethotoin | SCN10A|SCN11A|SCN1A|SCN2A|SCN3A|SCN4A|SCN5A|SCN7A|SCN8A|SCN9A | hydantoin antiepileptic | Details | |
| C02031 | BRD-K56792340 | ethoxyquin | antioxidant | Details | ||
| C02032 | BRD-K18131774 | ethoxzolamide | CA1|CA12|CA13|CA14|CA2|CA3|CA4|CA5A|CA5B|CA6|CA7|CA9 | carbonic anhydrase inhibitor | Details | |
| C02033 | BRD-K02464583 | ethyl-paraben | Details | |||
| C02034 | BRD-K47738867 | ethyl-pyruvate | HMGB1|TNF | tumor necrosis factor production inhibitor | Details | |
| C02035 | BRD-K82104468 | ethyl-vanillin | Details | |||
| C02036 | BRD-K21892374 | ethyl-2-(carbamoyloxy)benzoate | Details | |||
| C02037 | BRD-K82603084 | ethylenediaminetetraacetic-acid | PKC inhibitor | Details | ||
| C02038 | BRD-A68509429 | ethylnorepinephrine | bronchodilator | Details | ||
| C02039 | BRD-K46331928 | ethynodiol-diacetate | ESR1|PGR | Details | ||
| C02040 | BRD-K50417881 | eticlopride | DRD2|DRD3|DRD4 | dopamine receptor antagonist | Details | |
| C02041 | BRD-K37949327 | etidronic-acid | ATP6V1A|PTPRS | bone resorption inhibitor | Details | |
| C02042 | BRD-K63979671 | etifenin | renal function diagnostic agent | Details | ||
| C02043 | BRD-A60821666 | etifoxine | GABRA1|GABRA2|GABRA3|GABRA5 | GABA receptor modulator | Details | |
| C02044 | BRD-A09925278 | etilefrine | ADRA1A|ADRB1 | adrenergic receptor agonist | Details | |
| C02045 | BRD-K90982969 | etilevodopa | DRD3 | dopamine receptor agonist | Details | |
| C02046 | BRD-K68232413 | etizolam | GABRA1 | benzodiazepine receptor agonist | Details | |
| C02047 | BRD-A74667430 | etodolac | PTGS1|PTGS2|RXRA | cyclooxygenase inhibitor | Details | |
| C02048 | BRD-K73541271 | etofenamate | PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C02049 | BRD-K49338325 | etofibrate | PPARA | PPAR receptor agonist | Details | |
| C02050 | BRD-K83064458 | etofylline | ADORA1 | adenosine receptor antagonist | Details | |
| C02051 | BRD-K49840922 | etofylline-clofibrate | PPARA | platelet aggregation inhibitor | Details | |
| C02052 | BRD-K55055802 | etomidate | ADRA2B|GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRB1|GABRB2|GABRB3|GABRD|GABRE|GABRG1|GABRG2|GABRG3|GABRP|GABRQ | GABA receptor modulator | Details | |
| C02053 | BRD-K32405725 | etomoxir | CPT1A | carnitine palmitoyltransferase inhibitor | Details | |
| C02054 | BRD-A08302182 | etonogestrel | ESR1|PGR | progesterone receptor agonist | Details | |
| C02055 | BRD-K37798499 | etoposide | TOP2A|TOP2B | topoisomerase inhibitor | Details | |
| C02056 | BRD-K72533376 | etoposide-phosphate | TOP2A | topoisomerase inhibitor | Details | |
| C02057 | BRD-K54770957 | etoricoxib | PTGS2 | cyclooxygenase inhibitor | Details | |
| C02058 | BRD-K60914966 | etosalamide | anti-inflammatory agent | Details | ||
| C02059 | BRD-K51364817 | etoxybamide | Details | |||
| C02060 | BRD-K15858023 | ETP-45658 | PIK3CA|PIK3CB|PIK3CD|PIK3CG | PI3K inhibitor | Details | |
| C02061 | BRD-K24556407 | ETP-46464 | ATR kinase inhibitor | Details | ||
| C02062 | BRD-K74717603 | etravirine | CYP2C19|CYP2C9|CYP3A4 | non-nucleoside reverse transcriptase inhibitor | Details | |
| C02063 | BRD-K49076555 | etretinate | RARA|RARB|RARG|RXRA|RXRB|RXRG | protein synthesis inhibitor | Details | |
| C02064 | BRD-K29996876 | eucalyptol | ACHE | acetylcholinesterase inhibitor | Details | |
| C02065 | BRD-A37942872 | eucatropine | acetylcholine receptor antagonist | Details | ||
| C02066 | BRD-K32977963 | eugenol | AR | androgen receptor antagonist | Details | |
| C02067 | BRD-K19741031 | EUK-134 | APP|SOD2 | catalase stimulant | Details | |
| C02068 | BRD-K47031502 | eupatilin | mucus protecting agent | Details | ||
| C02069 | BRD-K16551357 | evacetrapib | CETP | cholesteryl ester transfer protein inhibitor | Details | |
| C02070 | BRD-K24548560 | evans-blue | GRIA1|PTPN1 | glutamate receptor negative allosteric modulator | Details | |
| C02071 | BRD-K11452913 | evatanepag | PTGER2|PTGER4 | prostaglandin inhibitor | Details | |
| C02072 | BRD-K13514097 | everolimus | MTOR | mTOR inhibitor | Details | |
| C02073 | BRD-A68631409 | evodiamine | TRPV1 | ATPase inhibitor; TRPV agonist | Details | |
| C02074 | BRD-K71603915 | EVP-6124 | CHRNA7 | acetylcholine receptor agonist | Details | |
| C02075 | BRD-K68395654 | EVP4593 | NFkB pathway inhibitor | Details | ||
| C02076 | BRD-K74396648 | EW-7197 | ACVR1B|TGFBR1 | TGF beta receptor inhibitor | Details | |
| C02077 | BRD-A73908300 | EX-527 | SIRT1 | SIRT inhibitor | Details | |
| C02078 | BRD-K12609457 | exalamide | membrane permeability inhibitor | Details | ||
| C02079 | BRD-K35304636 | examorelin | GHRHR|GHSR | growth hormone releasing factor agonist | Details | |
| C02080 | BRD-K92150287 | exatecan-mesylate | TOP1 | topoisomerase inhibitor | Details | |
| C02081 | BRD-K33425534 | exemestane | CYP19A1 | aromatase inhibitor | Details | |
| C02082 | BRD-K05505104 | exenatide | GLP1R | GLP receptor agonist | Details | |
| C02083 | BRD-K81795818 | exherin | CDH2 | cadherin antagonist | Details | |
| C02084 | BRD-K65716359 | exifone | TYR | nootropic agent | Details | |
| C02085 | BRD-K37708699 | exisulind | PDE5A | phosphodiesterase inhibitor | Details | |
| C02086 | BRD-K96155658 | exo-IWR-1 | TNKS | WNT signaling inhibitor negative control | Details | |
| C02087 | BRD-K78633253 | EXO-1 | ARF inhibitor | Details | ||
| C02088 | BRD-K98963219 | ezatiostat | GSTP1 | glutathione transferase inhibitor | Details | |
| C02089 | BRD-A41519720 | ezetimibe | ANPEP|NPC1L1|SOAT1 | cholesterol inhibitor; Niemann-Pick C1-like 1 protein antagonist | Details | |
| C02090 | BRD-K25570267 | ezutromid | UTRN | utrophin enhancer | Details | |
| C02091 | BRD-K05444225 | E7449 | PARP1|PARP2|TNKS|TNKS2 | PARP inhibitor | Details | |
| C02092 | BRD-K87948281 | F-11440 | HTR1A | serotonin receptor agonist | Details | |
| C02093 | BRD-A25619068 | fadrozole | CYP11B1|CYP19A1 | aromatase inhibitor | Details | |
| C02094 | BRD-K61536264 | fagomine | GLB1 | glucosidase inhibitor | Details | |
| C02095 | BRD-K08251020 | falecalcitriol | VDR | vitamin D receptor agonist | Details | |
| C02096 | BRD-K45033733 | famciclovir | DNA polymerase inhibitor | Details | ||
| C02097 | BRD-K00673382 | famotidine | HRH2 | histamine receptor antagonist | Details | |
| C02098 | BRD-A08255417 | famprofazone | cyclooxygenase inhibitor | Details | ||
| C02099 | BRD-K08998509 | fananserin | HTR2A | dopamine receptor antagonist; serotonin receptor antagonist | Details | |
| C02100 | BRD-K60798049 | fanetizole | neutrophil superoxide production | Details |