CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C00601 | BRD-K83359602 | barbital | CHRNA4|CHRNA7|GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GRIA2|GRIK2 | sedative | Details | |
| C00602 | BRD-K20545304 | bardoxolone | NOS2|PPARG | nuclear factor erythroid derived; like (NRF2) activator | Details | |
| C00603 | BRD-K69694239 | bardoxolone-methyl | PPARG|STAT3 | nuclear factor erythroid derived; like (NRF2) activator | Details | |
| C00604 | BRD-K53581288 | baricitinib | JAK1|JAK2 | JAK inhibitor | Details | |
| C00605 | BRD-K67760597 | barium-6-O-phosphonato-D-glucose | GPI | Details | ||
| C00606 | BRD-K78781788 | barnidipine | calcium channel blocker | Details | ||
| C00607 | BRD-K26362911 | basic-fuchsin | Details | |||
| C00608 | BRD-K62387885 | basimglurant | GRM5 | glutamate receptor antagonist | Details | |
| C00609 | BRD-K82818427 | batimastat | ADAM28|ADAMTS5|MMP12|MMP16|MMP2|MMP8 | matrix metalloprotease inhibitor | Details | |
| C00610 | BRD-K79595931 | bavisant | HRH3 | histamine receptor antagonist | Details | |
| C00611 | BRD-A18763547 | BAX-channel-blocker | BAX | cytochrome C release inhibitor | Details | |
| C00612 | BRD-A05457250 | BAY-K-8644-(+/-) | L-type calcium channel activator | Details | ||
| C00613 | BRD-K14329163 | BAY-K-8644-(s)-(-) | CACNA1C | L-type calcium channel activator | Details | |
| C00614 | BRD-K44471774 | bay-w-9798 | antioxidant | Details | ||
| C00615 | BRD-K15025317 | BAY-11-7082 | RELA | NFkB pathway inhibitor | Details | |
| C00616 | BRD-K48684885 | BAY-11-7085 | NFKBIA | NFkB pathway inhibitor | Details | |
| C00617 | BRD-K32033120 | BAY-41-2272 | GUCY1A3|GUCY1B3 | guanylyl cyclase activator | Details | |
| C00618 | BRD-K32952627 | BAY-60-6583 | ADORA1|ADORA2A|ADORA2B|ADORA3 | adenosine receptor agonist | Details | |
| C00619 | BRD-K86932920 | bay-60-7550 | PDE2A | phosphodiesterase inhibitor | Details | |
| C00620 | BRD-K53281329 | BAY-61-3606 | SYK | syk inhibitor | Details | |
| C00621 | BRD-A11731518 | BAY-85-8050 | Details | |||
| C00622 | BRD-K70463136 | BAY-87-2243 | HIF1A | hypoxia inducible factor inhibitor | Details | |
| C00623 | BRD-K90195324 | bazedoxifene | ESR1|ESR2 | selective estrogen receptor modulator (SERM) | Details | |
| C00624 | BRD-K66830666 | BAZ2-ICR | ZNF215 | bromodomain inhibitor | Details | |
| C00625 | BRD-K14646328 | BC-11 | PLAU | urokinase inhibitor | Details | |
| C00626 | BRD-K23672206 | BCI-540 | glutamate receptor agonist | Details | ||
| C00627 | BRD-K66541497 | BCTC | TRPV1 | TRPV antagonist | Details | |
| C00628 | BRD-K90472149 | BCX-1470 | CFD | serine protease inhibitor; complement inhibitor | Details | |
| C00629 | BRD-K17008822 | BD-1008 | sigma receptor antagonist | Details | ||
| C00630 | BRD-K36864847 | BD-1047 | SIGMAR1 | adrenergic receptor antagonist | Details | |
| C00631 | BRD-K29668683 | BD-1063 | SIGMAR1 | sigma receptor antagonist | Details | |
| C00632 | BRD-A24429032 | BE-2254 | ADRA1A | adrenergic receptor antagonist | Details | |
| C00633 | BRD-K44824027 | beclamide | anticonvulsant | Details | ||
| C00634 | BRD-A73385064 | beclomethasone | NR3C1|SERPINA6 | glucocorticoid receptor agonist | Details | |
| C00635 | BRD-K97810537 | beclomethasone-dipropionate | GPR97|NR3C1 | glucocorticoid receptor agonist | Details | |
| C00636 | BRD-K90817094 | bedaquiline | ATPase inhibitor | Details | ||
| C00637 | BRD-K99077012 | befuraline | Details | |||
| C00638 | BRD-K58319700 | begacestat | PSEN1 | gamma secretase inhibitor | Details | |
| C00639 | BRD-K73425385 | bekanamycin | bacterial 30S ribosomal subunit inhibitor | Details | ||
| C00640 | BRD-K17743125 | belinostat | HDAC1|HDAC10|HDAC11|HDAC2|HDAC3|HDAC4|HDAC5|HDAC6|HDAC7|HDAC8|HDAC9 | HDAC inhibitor | Details | |
| C00641 | BRD-K14993104 | bemegride | GABRA1 | chemoreceptor agonist | Details | |
| C00642 | BRD-A85587465 | bemesetron | HTR3A|HTR3B | serotonin receptor antagonist | Details | |
| C00643 | BRD-A92974210 | bemotrizinol | Details | |||
| C00644 | BRD-A90642009 | benaxibine | Details | |||
| C00645 | BRD-K49807096 | benazepril | ACE | angiotensin converting enzyme inhibitor | Details | |
| C00646 | BRD-K17068645 | bendamustine | DNA inhibitor | Details | ||
| C00647 | BRD-K19515365 | bendazac | PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C00648 | BRD-A80017228 | bendroflumethiazide | CA1|CA2|CA4|KCNMA1|SLC12A1|SLC12A3 | sodium/potassium/chloride transporter inhibitor | Details | |
| C00649 | BRD-K13473780 | benethamine | Details | |||
| C00650 | BRD-A22305049 | benfluorex | HMGCR | gluconeogenesis inhibitor | Details | |
| C00651 | BRD-K33903083 | benfluralin | CYP1A1|CYP1A2|CYP2B6|CYP3A4|ESR1|MMP1|SULT2A1|UGT1A1 | Details | ||
| C00652 | BRD-K07359318 | benfotiamine | AGER | antioxidant | Details | |
| C00653 | BRD-K97181463 | benidipine | CACNA1C|CACNA1G | calcium channel blocker | Details | |
| C00654 | BRD-K79425933 | benperidol | DRD2 | dopamine receptor antagonist | Details | |
| C00655 | BRD-A42423104 | benproperine | SCN5A | antitussive | Details | |
| C00656 | BRD-A61194565 | benserazide | DDC | DOPA decarboxylase inhibitor | Details | |
| C00657 | BRD-K89490285 | bentazepam | benzodiazepine receptor agonist | Details | ||
| C00658 | BRD-K58794715 | bentiromide | HPN | Details | ||
| C00659 | BRD-K88553858 | benurestat | urease inhibitor | Details | ||
| C00660 | BRD-K34234316 | benzalkonium | Cationic surfactant | Details | ||
| C00661 | BRD-K87158025 | benzamil | ASIC1|PKD2L1|SCNN1A|SCNN1B|SCNN1D|SCNN1G|SLC8A1 | sodium channel blocker | Details | |
| C00662 | BRD-K11717138 | benzbromarone | ABCC1 | chloride channel blocker | Details | |
| C00663 | BRD-A98083480 | benzenemethanol,-2,5-dimethyl-[[(1-methylethyl)amino]methyl] | Details | |||
| C00664 | BRD-K72723676 | benzethonium | SCN10A | sodium channel blocker | Details | |
| C00665 | BRD-K56156805 | benznidazole | DNA synthesis inhibitor | Details | ||
| C00666 | BRD-K55160477 | benzo[d]thiazole-2(3h)-thione | Details | |||
| C00667 | BRD-K75466013 | benzocaine | SCN10A | sodium channel blocker | Details | |
| C00668 | BRD-A45929034 | benzoclidine | Details | |||
| C00669 | BRD-K26556907 | benzofenac | Details | |||
| C00670 | BRD-K53397409 | benzoic-acid | DAO|HRSP12|PRDX5|RAB9A | food preservative | Details | |
| C00671 | BRD-A55748233 | benzoin | CES1 | Details | ||
| C00672 | BRD-K91699951 | benzonatate | SCN5A | local anesthetic | Details | |
| C00673 | BRD-K18772613 | benzoquinonium-dibromide | CHRNA1 | cholinergic receptor antagonist | Details | |
| C00674 | BRD-A87983072 | benzotript | CCKAR|CCKBR | CCK receptor antagonist | Details | |
| C00675 | BRD-K70327191 | benzoxiquine | antiinfective drug | Details | ||
| C00676 | BRD-K59986511 | benzoyl-peroxide | oxidizing agent | Details | ||
| C00677 | BRD-K20431737 | benzoylpas | Details | |||
| C00678 | BRD-K21450440 | benzthiazide | CA1|CA12|CA2|CA4|CA9|SLC12A3 | carbonic anhydrase inhibitor | Details | |
| C00679 | BRD-K48061146 | benztropine-mesylate | CHRM1|HRH1|SLC6A3 | acetylcholine receptor antagonist | Details | |
| C00680 | BRD-K28542495 | benzydamine | prostanoid receptor antagonist | Details | ||
| C00681 | BRD-K98494274 | benzyl-alcohol | local anesthetic | Details | ||
| C00682 | BRD-K52072429 | benzyl-benzoate | LIPE | lipase inhibitor | Details | |
| C00683 | BRD-K80253852 | benzyl-isothiocyanate | methylazoxymethanol acetate inhibitor | Details | ||
| C00684 | BRD-K23403298 | benzyldimethylhexadecylammonium | cationic surfactant | Details | ||
| C00685 | BRD-K11576103 | benzyldimethyloctylammonium | Details | |||
| C00686 | BRD-K55191674 | benzylpenicillin | penicillin binding protein inhibitor | Details | ||
| C00687 | BRD-K47878171 | bephenium-hydroxynaphthoate | anthelmintic agent | Details | ||
| C00688 | BRD-K98624455 | bepotastine | HRH1 | histamine receptor antagonist | Details | |
| C00689 | BRD-A91008255 | bepridil | ATP1A1|CACNA1A|CACNA1H|CACNA2D2|CALM1|KCNQ1|KCNQ4|PDE1A|PDE1B|TNNC1 | calcium channel blocker | Details | |
| C00690 | BRD-K14796088 | berberine | LDLR | LDL receptor activator | Details | |
| C00691 | BRD-K12968785 | bergapten | Details | |||
| C00692 | BRD-K04176066 | bergenin | IL1B|TNF | interleukin inhibitor | Details | |
| C00693 | BRD-K10196357 | besifloxacin | bacterial DNA gyrase inhibitor | Details | ||
| C00694 | BRD-K72735080 | BET-BAY-002 | bromodomain inhibitor | Details | ||
| C00695 | BRD-K38687824 | beta-amyloid-synthesis-inhibitor | APP | beta amyloid synthesis inhibitor | Details | |
| C00696 | BRD-K74225533 | beta-carotene | Details | |||
| C00697 | BRD-K87349602 | beta-CCB | GABRA1|GABRG2 | benzodiazepine receptor ligand | Details | |
| C00698 | BRD-K21045639 | beta-elemene | MMP2|MMP9 | apoptosis stimulant | Details | |
| C00699 | BRD-K95110148 | beta-funaltrexamine | OPRD1|OPRK1|OPRM1 | opioid receptor antagonist | Details | |
| C00700 | BRD-K39061174 | beta-glycerophosphoric-acid | Details |