CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C00301 | BRD-K15318383 | ammonium-glycyrrhizinate | HSD11B1|HSD11B2|SLCO1B1|SLCO1B3 | thrombin inhibitor | Details | |
| C00302 | BRD-M29182745 | ammonium-lactate | HCAR1 | Details | ||
| C00303 | BRD-K32531356 | ammonium-perfluorocaprylate | PIM1 | Pim kinase inhibitor | Details | |
| C00304 | BRD-K23335153 | AMN-082 | GRM7 | glutamate receptor modulator | Details | |
| C00305 | BRD-K91290917 | amodiaquine | HNMT | histamine receptor agonist | Details | |
| C00306 | BRD-K56334280 | amonafide | TOP2A|TOP2B | topoisomerase inhibitor | Details | |
| C00307 | BRD-A37390343 | amorolfine | membrane integrity inhibitor | Details | ||
| C00308 | BRD-K02265150 | amoxapine | ADRA1A|ADRA1B|ADRA1D|ADRA2A|ADRA2B|ADRA2C|CHRM1|CHRM2|CHRM3|CHRM4|CHRM5|DRD1|DRD2|DRD3|DRD4|DRD5|GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRB1|GABRB2|GABRB3|GABRD|GABRE|GABRG1|GABRG2|GABRG3|GABRP|GABRQ|HRH1|HRH4|HTR1A|HTR1B|HTR2A|HTR2B|HTR2C|HTR3A|HTR6|HTR7|SLC6A2|SLC6A3|SLC6A4 | norepinephrine reputake inhibitor | Details | |
| C00309 | BRD-K55044200 | amoxicillin | CYP2C19|SLC15A1|SLC15A2|SLC22A6 | penicillin binding protein inhibitor | Details | |
| C00310 | BRD-A34716233 | AMPA-(RS) | GRIN1 | glutamate receptor agonist | Details | |
| C00311 | BRD-K92493880 | AMPA-(S) | GRIN1 | glutamate receptor agonist | Details | |
| C00312 | BRD-K24771047 | ampalex | GRIA1|GRIA2|GRIA3|GRIA4 | glutamate receptor agonist | Details | |
| C00313 | BRD-K52397688 | amperozide | FAAH|HTR2A | dopamine receptor antagonist | Details | |
| C00314 | BRD-K27352494 | amphotericin-b | membrane permeability enhancer | Details | ||
| C00315 | BRD-K68432770 | ampicillin | bacterial cell wall synthesis inhibitor | Details | ||
| C00316 | BRD-A39172021 | ampiroxicam | PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C00317 | BRD-K47827687 | amprenavir | HIV protease inhibitor | Details | ||
| C00318 | BRD-K90027121 | amprolium | thiamine uptake blocker | Details | ||
| C00319 | BRD-K20484910 | ampyrone | cyclooxygenase inhibitor | Details | ||
| C00320 | BRD-K45924332 | amrinone | PDE3A|PDE3B|PDE4B|TNF | phosphodiesterase inhibitor | Details | |
| C00321 | BRD-K13843533 | amrubicin | TOP2A|TOP2B | topoisomerase inhibitor | Details | |
| C00322 | BRD-K68346641 | amsacrine | KCNH2|TOP2A | topoisomerase inhibitor | Details | |
| C00323 | BRD-K39670393 | amthamine | HRH2 | histamine receptor agonist | Details | |
| C00324 | BRD-K70924353 | amtolmetin-guacil | PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C00325 | BRD-K66538826 | amuvatinib | KIT|MET | FLT3 inhibitor; KIT inhibitor; PDGFR tyrosine kinase receptor inhibitor; RAD51 inhibitor; RET tyrosine kinase inhibitor | Details | |
| C00326 | BRD-K03504028 | amygdalin | CASP3 | caspase activator | Details | |
| C00327 | BRD-K03326591 | amyl-nitrite | NPR1 | atrial natriuretic peptide receptor agonist | Details | |
| C00328 | BRD-A09062839 | amyleine | local anesthetic | Details | ||
| C00329 | BRD-K93502141 | amylene-hydrate | local anesthetic | Details | ||
| C00330 | BRD-K00256256 | AMZ30 | protein phosphatase inhibitor | Details | ||
| C00331 | BRD-K88443722 | AM679 | ALOX5AP|CNR1|CNR2 | cannabinoid receptor agonist; lipoxygenase inhibitor | Details | |
| C00332 | BRD-A19609491 | ANA-12 | NTRK2 | tropomyosin receptor kinase inhibitor | Details | |
| C00333 | BRD-A24284985 | anabasine | acetylcholine receptor agonist | Details | ||
| C00334 | BRD-K44366189 | anacetrapib | CETP | cholesteryl ester transfer protein inhibitor | Details | |
| C00335 | BRD-K05355328 | anagliptin | DPP4 | dipeptidyl peptidase inhibitor | Details | |
| C00336 | BRD-K62200014 | anagrelide | PDE3A | phosphodiesterase inhibitor | Details | |
| C00337 | BRD-K01174345 | anamorelin | GHSR | growth hormone secretagogue receptor agonist | Details | |
| C00338 | BRD-K42352790 | anandamide | CACNA1G|CACNA1H|CACNA1I|CNR1|CNR2|GLRA1|GPR18|GPR55|KCNA2|KCNK3|KCNK9|TRPM8|TRPV1 | cannabinoid receptor agonist | Details | |
| C00339 | BRD-K52172416 | anastrozole | CYP19A1 | aromatase inhibitor | Details | |
| C00340 | BRD-K82164249 | andarine | AR | androgen receptor modulator | Details | |
| C00341 | BRD-A86619021 | andrographolide | NFKB1 | tumor necrosis factor production inhibitor | Details | |
| C00342 | BRD-A64011898 | androstenone | steroid | Details | ||
| C00343 | BRD-K12329651 | androsterone | androgen receptor agonist | Details | ||
| C00344 | BRD-A53566267 | anecortave-acetate | angiogenesis inhibitor | Details | ||
| C00345 | BRD-K49060658 | anethole | glutathione transferase stimulant | Details | ||
| C00346 | BRD-K92490248 | anethole-trithione | glutathione transferase stimulant | Details | ||
| C00347 | BRD-K45724504 | anguidine | SLC5A1 | protein synthesis inhibitor | Details | |
| C00348 | BRD-A75305484 | anidulafungin | fungal 1,3-beta-D-glucan synthase inhibitor | Details | ||
| C00349 | BRD-K88611939 | aniracetam | DRD2|GRIA1|GRIA2|GRIA3|GRIA4|HTR2A | glutamate receptor agonist | Details | |
| C00350 | BRD-K47458712 | anisindione | GGCX | vitamin K antagonist | Details | |
| C00351 | BRD-A29623586 | anisodamine | ADRA1A | lipid peroxidase inhibitor | Details | |
| C00352 | BRD-K91370081 | anisomycin | NHP2L1|RPL10L|RPL11|RPL13A|RPL15|RPL19|RPL23|RPL23A|RPL26L1|RPL3|RPL37|RPL8|RSL24D1 | DNA synthesis inhibitor | Details | |
| C00353 | BRD-A06771424 | anisotropine | CHRM1|CHRM2|CHRM3 | acetylcholine receptor antagonist | Details | |
| C00354 | BRD-K36949735 | anlotinib | KDR|PDGFRB | VEGFR inhibitor; PDGFR tyrosine kinase receptor inhibitor | Details | |
| C00355 | BRD-K55424922 | anpirtoline | HTR1B | serotonin receptor agonist | Details | |
| C00356 | BRD-K31170746 | ANR-94 | ADORA2A | A1 adenosine receptor antagonist | Details | |
| C00357 | BRD-K53252847 | ansamitocin-p-3 | apoptosis stimulant | Details | ||
| C00358 | BRD-K25863791 | antagonist-g | MAPK8 | neuropeptide receptor antagonist | Details | |
| C00359 | BRD-K01363385 | antalarmin | CRHR1 | corticosteroid releasing factor receptor antagonist | Details | |
| C00360 | BRD-K99300445 | antazoline | HRH1 | antihistamine | Details | |
| C00361 | BRD-K04725460 | anthralin | DNA synthesis inhibitor | Details | ||
| C00362 | BRD-K75167327 | anthranilic-acid | Details | |||
| C00363 | BRD-K15957397 | anthraquinone | CDC25B | CDC inhibitor | Details | |
| C00364 | BRD-A53836783 | antimony-potassium | Details | |||
| C00365 | BRD-A74328360 | antimonyl | Details | |||
| C00366 | BRD-A67709388 | antimycin-a | CYCS | ATP synthase inhibitor | Details | |
| C00367 | BRD-K15541734 | antioxine | Details | |||
| C00368 | BRD-K21920947 | AN2718 | leucyl-tRNA synthetase inhibitor | Details | ||
| C00369 | BRD-K32143970 | AP-18 | TRPA1 | transient receptor potential channel antagonist | Details | |
| C00370 | BRD-K20001883 | apabetalone | BRD3 | apolipoprotein expression enhancer | Details | |
| C00371 | BRD-K28115081 | apafant | PTAFR | platelet activating factor receptor antagonist | Details | |
| C00372 | BRD-K91308639 | apalutamide | androgen receptor antagonist | Details | ||
| C00373 | BRD-K25244359 | apatinib | CSK|KDR|KIT|RET | RET tyrosine kinase inhibitor | Details | |
| C00374 | BRD-K07449869 | APC-100 | AR | anti-inflammatory agent; androgen receptor antagonist | Details | |
| C00375 | BRD-K72748448 | APcK-110 | KIT|STAT3 | KIT inhibitor | Details | |
| C00376 | BRD-K86226872 | APD597 | GPR119 | glucose dependent insulinotropic receptor agonist | Details | |
| C00377 | BRD-K10859802 | APD668 | GPR119 | glucose dependent insulinotropic receptor agonist | Details | |
| C00378 | BRD-K85140930 | aphidicolin | RNA synthesis inhibitor | Details | ||
| C00379 | BRD-K26325692 | API-001 | SIGMAR1 | sigma receptor antagonist | Details | |
| C00380 | BRD-K97840621 | API-1 | AKT1|AKT2|AKT3 | AKT inhibitor | Details | |
| C00381 | BRD-K01493881 | apigenin | AKR1B1|AR|CDK6|CFTR|CYP19A1|CYP1B1|HSD17B1 | casein kinase inhibitor; cell proliferation inhibitor | Details | |
| C00382 | BRD-K67121414 | apixaban | F10 | coagulation factor inhibitor | Details | |
| C00383 | BRD-K64990520 | apocynin | NOX4 | NADPH oxidase inhibitor | Details | |
| C00384 | BRD-K15164005 | apoptosis-activator-II | BCHE|CES1 | carboxylesterase inhibitor | Details | |
| C00385 | BRD-A09004963 | APR-246 | TP53 | p53 activator | Details | |
| C00386 | BRD-K38911213 | apraclonidine | ADRA1A|ADRA2A|ADRA2B|ADRA2C | adrenergic receptor agonist | Details | |
| C00387 | BRD-K36062294 | apramycin | bacterial 30S ribosomal subunit inhibitor | Details | ||
| C00388 | BRD-K06883221 | apratastat | ADAM17|MMP1|MMP13|MMP9 | matrix metalloprotease inhibitor; tumor necrosis factor production inhibitor | Details | |
| C00389 | BRD-K93208532 | apremilast | PDE4A|PDE4B|PDE4C|PDE4D | phosphodiesterase inhibitor | Details | |
| C00390 | BRD-K65170927 | aprepitant | TACR1 | tachykinin antagonist | Details | |
| C00391 | BRD-K55172746 | apricitabine | nucleoside reverse transcriptase inhibitor | Details | ||
| C00392 | BRD-K53236343 | aprindine | CALM1|SCN5A | voltage-gated sodium channel blocker | Details | |
| C00393 | BRD-K63919159 | aptiganel | GRIN1 | glutamate receptor antagonist | Details | |
| C00394 | BRD-K68003372 | APTO-253 | KLF4 | kruppel-like factor expression enhancer | Details | |
| C00395 | BRD-K17511755 | APY-29 | ERN1 | serine/threonine kinase inhibitor | Details | |
| C00396 | BRD-K38627885 | APY0201 | IL12A|IL12B|PIKFYVE | phosphoinositide dependent kinase inhibitor | Details | |
| C00397 | BRD-K28383148 | AP1903 | Details | |||
| C00398 | BRD-K56032964 | AP26113 | ALK|EGFR | ALK tyrosine kinase receptor inhibitor | Details | |
| C00399 | BRD-K81729199 | AQ-RA741 | CHRM2 | acetylcholine receptor antagonist | Details | |
| C00400 | BRD-K67860401 | AR-A014418 | GSK3B | glycogen synthase kinase inhibitor | Details |