CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
stats1
stats2
6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C04601 | BRD-K27335680 | rhein | HSP90AA1 | Details | ||
| C04602 | BRD-K67772619 | rheochrysidin | PTPN1 | protein tyrosine kinase inhibitor | Details | |
| C04603 | BRD-K47169076 | rhodamine-123 | Details | |||
| C04604 | BRD-K79555887 | RI-1 | RAD51 | Details | ||
| C04605 | BRD-K60369935 | ribavirin | ADK|ENPP1|IMPDH1|IMPDH2|NT5C2 | antiviral | Details | |
| C04606 | BRD-K49313711 | ribitol | Details | |||
| C04607 | BRD-K36788280 | ribociclib | CDK4|CDK6 | CDK inhibitor | Details | |
| C04608 | BRD-K70246307 | riboflavin | BLVRB|RFK | vitamin B2 | Details | |
| C04609 | BRD-K09229706 | riboflavin-5-phosphate-sodium | BLVRB|DHODH|DPYD|HAO1|HAO2|MT-ND1|NOS1|PNPO|POR|PPCDC|RFK|RPS6KA4|SGK1 | Details | ||
| C04610 | BRD-K55188888 | ribostamycin | bacterial 30S ribosomal subunit inhibitor | Details | ||
| C04611 | BRD-A03826781 | ribostamycin-sulfate | P4HB | bacterial 30S ribosomal subunit inhibitor | Details | |
| C04612 | BRD-K33682646 | ricinoleic-acid | PTGER3 | prostanoid receptor agonist | Details | |
| C04613 | BRD-K30563334 | rifabutin | HSP90AA1|HSP90B1 | protein synthesis inhibitor | Details | |
| C04614 | BRD-K01507359 | rifampin | NR1I2|SLCO1A2|SLCO1B1|SLCO1B3 | RNA polymerase inhibitor | Details | |
| C04615 | BRD-K38512030 | rifamycin | SLCO1A2|SLCO1B1|SLCO1B3|SLCO2B1 | DNA directed RNA polymerase inhibitor | Details | |
| C04616 | BRD-K13277760 | rifamycin-sv | RNA synthesis inhibitor | Details | ||
| C04617 | BRD-K28346421 | rifapentine | CYP2C8|CYP2C9|CYP3A4 | RNA polymerase inhibitor | Details | |
| C04618 | BRD-K92838188 | rifaximin | NR1I2 | RNA synthesis inhibitor | Details | |
| C04619 | BRD-K55187425 | rigosertib | PLK1 | cell cycle inhibitor; PLK inhibitor | Details | |
| C04620 | BRD-K01638814 | rilmenidine | ADRA2A | adrenergic receptor agonist; imidazoline receptor agonist | Details | |
| C04621 | BRD-K06240250 | rilpivirine | NR1I2|SCN10A | non-nucleoside reverse transcriptase inhibitor | Details | |
| C04622 | BRD-K21283037 | riluzole | KCNK10|KCNK2|KCNK4|KCNN4|SCN10A|SCN11A|SCN1A|SCN2A|SCN3A|SCN4A|SCN5A|SCN7A|SCN8A|SCN9A|SLC7A11 | glutamate inhibitor | Details | |
| C04623 | BRD-A75479906 | rimantadine | antiviral; RNA synthesis inhibitor | Details | ||
| C04624 | BRD-K70490179 | rimcazole | SIGMAR1 | sigma receptor antagonist | Details | |
| C04625 | BRD-K31627533 | rimexolone | NR3C1|SERPINA6 | glucocorticoid receptor agonist | Details | |
| C04626 | BRD-K13296708 | rimonabant | CNR1|GPR55 | cannabinoid receptor antagonist | Details | |
| C04627 | BRD-K84783599 | riociguat | GUCY1A2|GUCY1A3|GUCY1B2|GUCY1B3 | guanylate cyclase stimulant | Details | |
| C04628 | BRD-K36379990 | riodipine | calcium channel blocker | Details | ||
| C04629 | BRD-K48963429 | riodoxol | other antibiotic | Details | ||
| C04630 | BRD-K53814070 | ripasudil | ROCK1|ROCK2 | rho associated kinase inhibitor | Details | |
| C04631 | BRD-K57427145 | ripazepam | GABRA1 | benzodiazepine receptor agonist | Details | |
| C04632 | BRD-K05185389 | risedronate | FDPS | osteoclast inhibitor | Details | |
| C04633 | BRD-K53857191 | risperidone | ADRA1A|ADRA1B|ADRA1D|ADRA2A|ADRA2B|ADRA2C|DRD1|DRD2|DRD3|DRD4|HRH1|HTR1A|HTR1B|HTR1D|HTR1E|HTR1F|HTR2A|HTR2C|HTR6|HTR7 | dopamine receptor antagonist; serotonin receptor antagonist | Details | |
| C04634 | BRD-K00317371 | RITA | MDM2 | MDM inhibitor | Details | |
| C04635 | BRD-K40887525 | ritanserin | ADRA1A|ADRA1B|ADRA1D|HTR1A|HTR1B|HTR1D|HTR2A|HTR2B|HTR2C|HTR5A|HTR6|HTR7 | serotonin receptor antagonist | Details | |
| C04636 | BRD-K14003026 | ritodrine | ADRB2 | adrenergic receptor agonist | Details | |
| C04637 | BRD-K51485625 | ritonavir | CYP1A2|CYP2B6|CYP2C19|CYP2C8|CYP2C9|CYP2D6|CYP2E1|CYP3A4|CYP3A5|CYP3A7 | HIV protease inhibitor | Details | |
| C04638 | BRD-K79966802 | rivanicline | CHRNA4|CHRNB2|CXCL8 | acetylcholine receptor agonist | Details | |
| C04639 | BRD-K37130656 | rivaroxaban | F10 | coagulation factor inhibitor | Details | |
| C04640 | BRD-K10706131 | rivastigmine | ACHE|BCHE | acetylcholinesterase inhibitor | Details | |
| C04641 | BRD-K75699339 | rizatriptan | HTR1A|HTR1B|HTR1D|HTR1E|HTR1F | serotonin receptor agonist | Details | |
| C04642 | BRD-K19333160 | RKI-1447 | CDC42BPA|DMPK|LIMK1|MYLK|PAK1|PKN1|ROCK1|ROCK2 | rho associated kinase inhibitor | Details | |
| C04643 | BRD-K28773847 | RLX | Details | |||
| C04644 | BRD-K41415459 | RN-1 | KDM1A | histone demethylase inhibitor | Details | |
| C04645 | BRD-K95581532 | RN-1734 | TRPV4 | TRPV antagonist | Details | |
| C04646 | BRD-K45519571 | RN-1747 | TRPV4 | TRPV agonist | Details | |
| C04647 | BRD-A63546914 | Ro-04-5595 | GRIN2B | Details | ||
| C04648 | BRD-K00486786 | Ro-08-2750 | NGF | Details | ||
| C04649 | BRD-K79684402 | Ro-10-5824 | DRD4 | dopamine receptor agonist | Details | |
| C04650 | BRD-A53134341 | Ro-106-9920 | NFkB pathway inhibitor | Details | ||
| C04651 | BRD-K77220725 | Ro-1138452 | PTGIR | prostanoid receptor antagonist | Details | |
| C04652 | BRD-K82823076 | Ro-15-4513 | GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRB2|GABRG2 | Details | ||
| C04653 | BRD-K80778372 | Ro-19-4605 | GABRA1|GABRA2|GABRA3|GABRA5 | Details | ||
| C04654 | BRD-A07207424 | Ro-20-1724 | PDE3A|PDE4A|PDE4B|PDE4C|PDE4D | phosphodiesterase inhibitor | Details | |
| C04655 | BRD-K51541829 | Ro-25-6981 | GRIN2B | Details | ||
| C04656 | BRD-K21672174 | Ro-28-1675 | GCK | glucokinase activator | Details | |
| C04657 | BRD-K00354853 | RO-3 | P2RX3 | purinergic receptor antagonist | Details | |
| C04658 | BRD-K78373679 | Ro-3306 | CDK1 | CDK inhibitor | Details | |
| C04659 | BRD-K55192287 | Ro-48-8071 | LSS | oxidosqualene cyclase inhibitor | Details | |
| C04660 | BRD-K64538373 | Ro-4987655 | MAP2K1 | MEK inhibitor | Details | |
| C04661 | BRD-K82804538 | Ro-5126766 | BRAF|MAP2K1|MAP2K2|RAF1 | RAF inhibitor; MEK inhibitor | Details | |
| C04662 | BRD-K28007504 | Ro-60-0175 | HTR2A|HTR2B|HTR2C | Details | ||
| C04663 | BRD-K12639498 | Ro-61-8048 | KMO | kynurenine 3-monooxygenase inhibitor | Details | |
| C04664 | BRD-K91333421 | Ro-67-7476 | GRM1 | glutamate receptor positive allosteric modulator | Details | |
| C04665 | BRD-K58299615 | Ro-90-7501 | APP | Details | ||
| C04666 | BRD-K57284066 | Ro-9187 | HCV inhibitor | Details | ||
| C04667 | BRD-K26169680 | robalzotan | HTR1A | serotonin receptor antagonist | Details | |
| C04668 | BRD-K33610132 | rociletinib | EGFR | EGFR inhibitor | Details | |
| C04669 | BRD-K43305603 | rocuronium | CHRM2|CHRNA2|HTR3A | acetylcholine receptor antagonist | Details | |
| C04670 | BRD-K21733600 | rofecoxib | ELN|PTGS2 | cyclooxygenase inhibitor | Details | |
| C04671 | BRD-K03194791 | roflumilast | PDE4A|PDE4B|PDE4C|PDE4D | phosphodiesterase inhibitor | Details | |
| C04672 | BRD-A34255068 | rolipram | phosphodiesterase inhibitor | Details | ||
| C04673 | BRD-K75516118 | rolipram-R(-) | PDE4A|PDE4B|PDE4C|PDE4D|PDE5A | phosphodiesterase inhibitor | Details | |
| C04674 | BRD-K65856711 | rolipram-S(+) | phosphodiesterase inhibitor | Details | ||
| C04675 | BRD-A62336573 | rolitetracycline | bacterial 30S ribosomal subunit inhibitor | Details | ||
| C04676 | BRD-K38564664 | rolziracetam | Details | |||
| C04677 | BRD-K61397605 | romidepsin | HDAC1|HDAC2|HDAC3|HDAC4|HDAC5|HDAC6|HDAC7|HDAC8|HDAC9 | HDAC inhibitor | Details | |
| C04678 | BRD-K94266545 | ronidazole | antiprotozoal agent | Details | ||
| C04679 | BRD-K15933101 | ropinirole | ADRA2A|ADRA2B|ADRA2C|DRD1|DRD2|DRD3|DRD4|DRD5|HTR1A|HTR1B|HTR1D|HTR2A|HTR2B|HTR2C | dopamine receptor agonist | Details | |
| C04680 | BRD-K50938786 | ropivacaine | SCN10A | sodium channel blocker | Details | |
| C04681 | BRD-K03384561 | roquinimex | angiogenesis inhibitor; tumor necrosis factor production inhibitor | Details | ||
| C04682 | BRD-A38799180 | rosamicin | protein synthesis inhibitor | Details | ||
| C04683 | BRD-K07691486 | roscovitine | CDK2|CDK9 | CDK inhibitor | Details | |
| C04684 | BRD-K33623053 | rose-bengal | contrast agent | Details | ||
| C04685 | BRD-K36163066 | rose-bengal-lactone | coloring agent | Details | ||
| C04686 | BRD-A97437073 | rosiglitazone | ACSL4|FFAR1|PPARG|TRPC5|TRPM3 | insulin sensitizer; PPAR receptor agonist | Details | |
| C04687 | BRD-K20313525 | rosmarinic-acid | MCL1|TYR | GABA transaminase inhibitor | Details | |
| C04688 | BRD-K49841478 | rosoxacin | topoisomerase inhibitor | Details | ||
| C04689 | BRD-K11672787 | rostafuroxine | ATP1A1 | ATPase inhibitor | Details | |
| C04690 | BRD-K82941592 | rosuvastatin | HMGCR | HMGCR inhibitor | Details | |
| C04691 | BRD-K91111634 | rotigotine | ADRA2B|DRD1|DRD2|DRD3|DRD4|DRD5|HTR1A | dopamine receptor agonist | Details | |
| C04692 | BRD-K35719256 | rotundine | DRD1|DRD2|DRD3|HTR1A | serotonin receptor agonist | Details | |
| C04693 | BRD-K22685337 | roxarsone | antiprotozoal agent | Details | ||
| C04694 | BRD-K81855038 | roxatidine-acetate | HRH2 | histamine receptor antagonist | Details | |
| C04695 | BRD-K38684403 | roxithromycin | ABCB1|MLNR | bacterial 50S ribosomal subunit inhibitor | Details | |
| C04696 | BRD-A29148886 | RP-001 | S1PR1 | sphingosine 1 phosphate receptor agonist | Details | |
| C04697 | BRD-K40767677 | RP67580 | Details | |||
| C04698 | BRD-K87973152 | RQ-00203078 | TRPM8 | transient receptor potential channel antagonist | Details | |
| C04699 | BRD-K06894065 | RRx-001 | G6PD | glucose 6-phosphate dehydrogenase inhibitor | Details | |
| C04700 | BRD-A00055058 | RS-0481 | immunostimulant | Details |