CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
stats1
stats2
6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C05301 | BRD-A94008949 | telithromycin | CYP1A2|CYP2D6|CYP3A4|CYP3A5|CYP3A7 | bacterial 30S ribosomal subunit inhibitor; bacterial 50S ribosomal subunit inhibitor | Details | |
| C05302 | BRD-A05523972 | telmesteine | mucolytic agent | Details | ||
| C05303 | BRD-K73999723 | telmisartan | AGTR1|PPARG | angiotensin receptor antagonist | Details | |
| C05304 | BRD-K63178091 | telotristat | TPH1 | tryptophan hydroxylase inhibitor | Details | |
| C05305 | BRD-K94559059 | telotristat-ethyl | TPH1 | tryptophan hydroxylase inhibitor | Details | |
| C05306 | BRD-A93093700 | temazepam | GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRB1|GABRB2|GABRB3|GABRD|GABRE|GABRG1|GABRG2|GABRG3|GABRP|GABRQ|GABRR1|GABRR2|GABRR3|TSPO | benzodiazepine receptor agonist | Details | |
| C05307 | BRD-K51805276 | temefos | cholinesterase inhibitor | Details | ||
| C05308 | BRD-K10784860 | temocapril | ACE | angiotensin converting enzyme inhibitor | Details | |
| C05309 | BRD-K63712959 | temoporfin | radical formation stimulant | Details | ||
| C05310 | BRD-K32107296 | temozolomide | MGMT | DNA alkylating agent | Details | |
| C05311 | BRD-K95053546 | tempol | free radical scavenger | Details | ||
| C05312 | BRD-K42898655 | temsirolimus | MTOR | mTOR inhibitor | Details | |
| C05313 | BRD-A42270467 | tenatoprazole | IDO1 | ATPase inhibitor | Details | |
| C05314 | BRD-K48068743 | teneligliptin | DPP4 | dipeptidyl peptidase inhibitor | Details | |
| C05315 | BRD-A87479750 | tenidap | KCNJ4|PTGS1 | cyclooxygenase inhibitor | Details | |
| C05316 | BRD-A41835910 | tenilsetam | AGE inhibitor | Details | ||
| C05317 | BRD-K10362825 | teniposide | TOP2A|TOP2B | topoisomerase inhibitor | Details | |
| C05318 | BRD-K15891719 | tenofovir | HIV integrase inhibitor; nucleoside reverse transcriptase inhibitor | Details | ||
| C05319 | BRD-A25988899 | tenofovir-alafenamide | nucleoside reverse transcriptase inhibitor | Details | ||
| C05320 | BRD-K61868322 | tenofovir-disoproxil | CYP1A2 | nucleoside reverse transcriptase inhibitor | Details | |
| C05321 | BRD-K05977823 | tenovin-1 | SIRT1 | SIRT inhibitor; TP53 activator | Details | |
| C05322 | BRD-K13949769 | tenovin-6 | SIRT1|SIRT2|SIRT3 | SIRT inhibitor | Details | |
| C05323 | BRD-A22844106 | tenoxicam | PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C05324 | BRD-K91298281 | tenylidone | Details | |||
| C05325 | BRD-K89714990 | tepoxalin | ALOX5 | cyclooxygenase inhibitor; lipoxygenase inhibitor | Details | |
| C05326 | BRD-A18279961 | TEPP-46 | PKM | pyruvate kinase isozyme activator | Details | |
| C05327 | BRD-K11510141 | teprenone | mucus protecting agent | Details | ||
| C05328 | BRD-K76788410 | terameprocol | BIRC5|CDK1 | lipoxygenase inhibitor | Details | |
| C05329 | BRD-A22256192 | terazosin | ADRA1A|ADRA1B|ADRA1D|KCNH2|KCNH6|KCNH7 | adrenergic receptor antagonist | Details | |
| C05330 | BRD-K68132782 | terbinafine | SQLE | fungal squalene epoxidase inhibitor | Details | |
| C05331 | BRD-A50157456 | terbutaline | ADRB2 | adrenergic receptor agonist | Details | |
| C05332 | BRD-A11725667 | terciprazine | Details | |||
| C05333 | BRD-K86204871 | terconazole | sterol demethylase inhibitor | Details | ||
| C05334 | BRD-A06352418 | terfenadine | CHRM1|CHRM2|CHRM3|CHRM4|CHRM5|HRH1|KCNH1|KCNH2 | histamine receptor antagonist | Details | |
| C05335 | BRD-A89207210 | terguride | ADRA1A|ADRA2A|ADRA2B|ADRA2C|DRD2|DRD3|DRD4|HTR1A|HTR1B|HTR1D|HTR2A|HTR2B|HTR2C | dopamine receptor agonist; serotonin receptor antagonist | Details | |
| C05336 | BRD-A42699921 | teriflunomide | DHODH | dihydroorotate dehydrogenase inhibitor | Details | |
| C05337 | BRD-K73451719 | terlipressin | AVPR1A|AVPR1B|AVPR2 | vasopressin receptor agonist | Details | |
| C05338 | BRD-A33479817 | terodiline | cholinergic receptor antagonist | Details | ||
| C05339 | BRD-A39935389 | teroxirone | DNA inhibitor | Details | ||
| C05340 | BRD-K93396439 | terpene | Details | |||
| C05341 | BRD-A64228451 | terreic-acid-(-) | BTK | Bruton's tyrosine kinase (BTK) inhibitor | Details | |
| C05342 | BRD-K43975632 | terutroban | TBXA2R | prostanoid receptor antagonist | Details | |
| C05343 | BRD-K15507868 | tesaglitazar | PPARA|PPARG | insulin sensitizer; PPAR receptor agonist | Details | |
| C05344 | BRD-K69636617 | testolactone | CYP19A1 | aromatase inhibitor | Details | |
| C05345 | BRD-A55393291 | testosterone | AR | androgen receptor agonist | Details | |
| C05346 | BRD-K89657519 | testosterone-enanthate | AR | androgen receptor agonist | Details | |
| C05347 | BRD-A48720949 | testosterone-propionate | AR | androgen receptor agonist | Details | |
| C05348 | BRD-K70650177 | testosterone-undecanoate | AR | androgen receptor agonist | Details | |
| C05349 | BRD-K95739795 | tetrabenazine | DRD2|SLC18A1|SLC18A2 | vesicular monoamine transporter inhibitor | Details | |
| C05350 | BRD-K45071273 | tetracaine | SCN10A|SCN11A|SCN1A|SCN2A|SCN3A|SCN4A|SCN5A|SCN7A|SCN8A|SCN9A | membrane integrity inhibitor | Details | |
| C05351 | BRD-A34788695 | tetracycline | PRNP | bacterial 30S ribosomal subunit inhibitor | Details | |
| C05352 | BRD-K47539947 | tetradecylthioacetic-acid | lipid peroxidase inhibitor | Details | ||
| C05353 | BRD-K41298358 | tetraethylenepentamine | SOD1|SOD2 | superoxide dismutase inhibitor | Details | |
| C05354 | BRD-A36978621 | tetrahydrofolic-acid | ALDH1L1|AMT|ATIC|FOLR2|FTCD|MTFMT|MTHFD1|MTHFD2|MTHFR|MTR|SHMT1|SHMT2 | Details | ||
| C05355 | BRD-A91831168 | tetrahydropapaverine | Details | |||
| C05356 | BRD-A86248581 | tetrahydrouridine | CDA | cytidine deaminase inhibitor | Details | |
| C05357 | BRD-A28856712 | tetrahydrozoline | adrenergic receptor agonist | Details | ||
| C05358 | BRD-K36889451 | tetramethylthiuram-monosulfide | Details | |||
| C05359 | BRD-A46393198 | tetramisole | immunostimulant | Details | ||
| C05360 | BRD-K08078237 | tetrandrine | SLC6A3 | calcium channel blocker | Details | |
| C05361 | BRD-A14757586 | tetrazol-5-yl-glycine-(RS) | GRIN1|GRIN2A|GRIN2B|GRIN2C|GRIN2D | glutamate receptor agonist | Details | |
| C05362 | BRD-A52660433 | tetrindole | MAOA | monoamine oxidase inhibitor | Details | |
| C05363 | BRD-K90177246 | tetroquinone | Details | |||
| C05364 | BRD-K97101532 | tezacaftor | CFTR channel agonist | Details | ||
| C05365 | BRD-K57708067 | TFC-007 | HPGDS | prostaglandin inhibitor | Details | |
| C05366 | BRD-K97072811 | TG-003 | CLK1|CLK4|DYRK1A|DYRK1B | CLK inhibitor | Details | |
| C05367 | BRD-K14560436 | TG-02 | CDK1|CDK2|CDK7|CDK9|FLT3|JAK2 | CDK inhibitor; FLT3 inhibitor; JAK inhibitor | Details | |
| C05368 | BRD-K18424115 | TG-100572 | KDR|SRC | src inhibitor; VEGFR inhibitor | Details | |
| C05369 | BRD-K46392623 | TG-100713 | PI3K inhibitor | Details | ||
| C05370 | BRD-K12735121 | TG-100801 | FGFR1|FLT1|KDR|SRC | src inhibitor; VEGFR inhibitor | Details | |
| C05371 | BRD-K39841531 | TG-101209 | JAK2|JAK3 | JAK inhibitor | Details | |
| C05372 | BRD-K12502280 | TG-101348 | BRD4|JAK1|JAK2|JAK3|TYK2 | FLT3 inhibitor; JAK inhibitor | Details | |
| C05373 | BRD-K52579889 | TGR-1202 | PI3K inhibitor | Details | ||
| C05374 | BRD-A41692738 | TGX-221 | PIK3CB|PIK3CD | PI3K inhibitor | Details | |
| C05375 | BRD-K64785675 | TG100-115 | PIK3CA|PIK3CB|PIK3CD|PIK3CG | PI3K inhibitor | Details | |
| C05376 | BRD-K20958582 | TH-302 | DNA alkylating agent | Details | ||
| C05377 | BRD-K87548127 | thaliblastine | DNA inhibitor | Details | ||
| C05378 | BRD-A93255169 | thalidomide | CRBN|FGFR2|NFKB1|ORM1|ORM2|PTGS2|TNF | tumor necrosis factor production inhibitor | Details | |
| C05379 | BRD-K34888156 | theobromine | ADORA1|ADORA2A|PDE4B | phosphodiesterase inhibitor | Details | |
| C05380 | BRD-K97799481 | theophylline | adenosine receptor antagonist | Details | ||
| C05381 | BRD-K38380126 | thiamet-g | MGEA5 | GLCNAC phosphotransferase inhibitor | Details | |
| C05382 | BRD-K95785345 | thiamine | SLC19A2|SLC19A3|TPK1 | vitamin B | Details | |
| C05383 | BRD-A09994331 | thiamine-pyrophosphate | Details | |||
| C05384 | BRD-K79711234 | thiamphenicol | bacterial 50S ribosomal subunit inhibitor | Details | ||
| C05385 | BRD-A23970436 | thiamylal | GABRA1|KCNJ11|KCNJ8 | glutamate receptor antagonist | Details | |
| C05386 | BRD-K03164761 | thiazovivin | rho associated kinase inhibitor | Details | ||
| C05387 | BRD-K69600043 | thiethylperazine | DRD1|DRD2|DRD4 | dopamine receptor antagonist | Details | |
| C05388 | BRD-K26619122 | thiocolchicoside | GABRA1|GABRB2|GABRG2|GLRA1|GLRB | GABA receptor antagonist | Details | |
| C05389 | BRD-A16347691 | thioctic-acid | ACHE|LIAS|LIPT1|PTGS2|SLC5A6 | reducing agent | Details | |
| C05390 | BRD-K54521836 | thiodiglycol | Details | |||
| C05391 | BRD-K49350383 | thioguanine | IMPDH1|IMPDH2 | purine antagonist | Details | |
| C05392 | BRD-K61443650 | thiomersal | OXCT1 | other antibiotic | Details | |
| C05393 | BRD-A72603112 | thiopental | CHRNA4|CHRNA7|FAAH|GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GRIA2|GRIK2 | GABA receptor antagonist | Details | |
| C05394 | BRD-K63874012 | thioperamide | HRH3|HRH4 | histamine receptor antagonist | Details | |
| C05395 | BRD-K90168339 | thiophanate | Details | |||
| C05396 | BRD-K08619574 | thioproperazine | ADRA1A|ADRA1B|DRD1|DRD2|HTR1A|HTR2A | dopamine receptor antagonist | Details | |
| C05397 | BRD-A84481105 | thioridazine | ADRA1A|ADRA1B|DRD1|DRD2|DRD3|DRD4|DRD5|HRH1|HTR1A|HTR2A|HTR2C|HTR6|HTR7|KCNH2 | dopamine receptor antagonist | Details | |
| C05398 | BRD-A56012032 | thiorphan | MME | membrane metalloendopeptidase inhibitor | Details | |
| C05399 | BRD-A20697603 | thiostrepton | FOXM1 | FOXM1 inhibitor; protein synthesis inhibitor | Details | |
| C05400 | BRD-K09631521 | thiotepa | CYP2B6|CYP3A4 | cytochrome P450 inhibitor | Details |