CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C04201 | BRD-K73381542 | phenylephrine | ADRA1A|ADRA1B|ADRA1D | adrenergic receptor agonist | Details | |
| C04202 | BRD-K42371134 | phenylethyl-alcohol | Details | |||
| C04203 | BRD-K74193284 | phenylmercuric-acetate | other antifungal | Details | ||
| C04204 | BRD-K33422401 | phenylmethylsulfonyl-fluoride | serine protease inhibitor | Details | ||
| C04205 | BRD-A65683612 | phenylpiracetam | noradrenaline uptake inhibitor | Details | ||
| C04206 | BRD-K55930204 | phenytoin | SCN10A|SCN11A|SCN1A|SCN2A|SCN3A|SCN4A|SCN5A|SCN7A|SCN8A|SCN9A | hydantoin antiepileptic | Details | |
| C04207 | BRD-K44400149 | PhiKan-083 | TP53 | p53 stabilizing agent | Details | |
| C04208 | BRD-K15563106 | phloretin | AQP9|CLCN3|SLC23A1 | sodium/glucose cotransporter inhibitor | Details | |
| C04209 | BRD-K24601397 | phlorizin | SLC5A1|SLC5A11|SLC5A2|SLC5A3 | sodium/glucose cotransporter inhibitor | Details | |
| C04210 | BRD-K00405906 | phloroglucin | Details | |||
| C04211 | BRD-K74558903 | phortress | AHR | aryl hydrocarbon receptor ligand | Details | |
| C04212 | BRD-U51753822 | phosphatidylcholine | PCTP | Details | ||
| C04213 | BRD-K07460388 | PHP-501 | GABRA1|GABRB2|GABRG2 | GABA receptor antagonist | Details | |
| C04214 | BRD-K59745944 | PHT-427 | AKT2|PDPK1 | AKT inhibitor; pyruvate dehydrogenase inhibitor | Details | |
| C04215 | BRD-K77115421 | phthalylsulfacetamide | Details | |||
| C04216 | BRD-K64659768 | phthalylsulfathiazole | dihydropteroate synthetase inhibitor | Details | ||
| C04217 | BRD-K76568384 | PHTPP | ESR2 | estrogen receptor antagonist | Details | |
| C04218 | BRD-K25650355 | physostigmine | ACHE|BCHE | cholinesterase inhibitor | Details | |
| C04219 | BRD-K25650355 | physostigmine-salicylate | acetylcholinesterase inhibitor | Details | ||
| C04220 | BRD-K76661572 | phytonadione | BGLAP|GGCX | Details | ||
| C04221 | BRD-K05048137 | phytosphingosine | Details | |||
| C04222 | BRD-K67868012 | PI-103 | MTOR|PIK3CA|PIK3CB|PIK3CD|PIK3CG|PRKDC | mTOR inhibitor; PI3K inhibitor | Details | |
| C04223 | BRD-K97365803 | PI-828 | PI3K inhibitor | Details | ||
| C04224 | BRD-K79132813 | pibenzimol | DNA inhibitor | Details | ||
| C04225 | BRD-K02750403 | piboserod | HTR2B|HTR4 | serotonin receptor antagonist | Details | |
| C04226 | BRD-A71765060 | picartamide | ATP4A | H+/K+-ATPase inhibitor | Details | |
| C04227 | BRD-K91509126 | piceatannol | ATP5A1|ATP5B|ATP5C1|IRF3 | SYK inhibitor | Details | |
| C04228 | BRD-K47642186 | piclamilast | PDE4A|PDE4B|PDE4C|PDE4D | phosphodiesterase inhibitor | Details | |
| C04229 | BRD-K68653965 | picolamine | Details | |||
| C04230 | BRD-K01029106 | picolinic-acid | chelating agent | Details | ||
| C04231 | BRD-K28492574 | piconol | Details | |||
| C04232 | BRD-K67277431 | picotamide | TBXA2R | thromboxane receptor antagonist; thromboxane synthase inhibitor | Details | |
| C04233 | BRD-A91822151 | picrotin | GABRA1|GABRR1|GLRA1|GLRA2|GLRA3|GLRB | GABA receptor antagonist | Details | |
| C04234 | BRD-K36461289 | picrotoxinin | GLRA1|GLRA2|GLRA3|GLRB|HTR3A|HTR3B | GABA receptor antagonist | Details | |
| C04235 | BRD-K57313110 | pidolic-acid | ADAM28|AMY1A|AMY2A|AMY2B|ANG|CCL8|HCRT|IGLC1|KRTAP5-2|TFF2|VEGFA | Details | ||
| C04236 | BRD-K44442813 | pidotimod | interferon receptor agonist; interleukin receptor agonist | Details | ||
| C04237 | BRD-K66874953 | pifithrin-alpha | TP53 | TP53 inhibitor | Details | |
| C04238 | BRD-K31792052 | pifithrin-cyclic | TP53 | TP53 inhibitor | Details | |
| C04239 | BRD-K96799727 | pifithrin-mu | HSPA1A|TP53 | HSP inhibitor | Details | |
| C04240 | BRD-K30977212 | PIK-293 | PIK3CA|PIK3CB|PIK3CD|PIK3CG | PI3K inhibitor | Details | |
| C04241 | BRD-K50631926 | PIK-294 | PIK3CB|PIK3CD|PIK3CG | PI3K inhibitor | Details | |
| C04242 | BRD-K49371609 | PIK-75 | PIK3CA|PIK3CB|PIK3CD|PIK3CG|PRKDC | DNA protein kinase inhibitor; PI3K inhibitor | Details | |
| C04243 | BRD-K29395450 | PIK-93 | PI4KB|PIK3C3|PIK3CG | PI3K inhibitor | Details | |
| C04244 | BRD-K56691760 | pikamilone | Details | |||
| C04245 | BRD-A85548292 | piketoprofen | cyclooxygenase inhibitor | Details | ||
| C04246 | BRD-K49456274 | pilaralisib | PI3K inhibitor | Details | ||
| C04247 | BRD-K85090592 | pilocarpine | CHRM1|CHRM2|CHRM3|CHRM4|CHRM5 | acetylcholine receptor agonist | Details | |
| C04248 | BRD-K83245588 | pilsicainide | SCN5A | sodium channel blocker | Details | |
| C04249 | BRD-K48832421 | PIM-1-Inhibitor-2 | PIM1 | Pim kinase inhibitor | Details | |
| C04250 | BRD-K83405785 | pimavanserin | DRD2|HTR2A | serotonin receptor inverse agonist | Details | |
| C04251 | BRD-K92107055 | pimecrolimus | FKBP1A|MTOR | calcineurin inhibitor | Details | |
| C04252 | BRD-K88090157 | pimethixene | antihistamine | Details | ||
| C04253 | BRD-A84575140 | pimobendan | PDE3A | calcium sensitizer; phosphodiesterase inhibitor | Details | |
| C04254 | BRD-A67521319 | pimonidazole | Details | |||
| C04255 | BRD-K01292756 | pimozide | CACNA1I|CALM1|DRD1|DRD2|DRD3|DRD4|DRD5|HRH1|HTR1A|HTR2A|KCNA10|KCNH2 | dopamine receptor antagonist | Details | |
| C04256 | BRD-A43882281 | pinacidil | ABCC8|ABCC9 | ATP channel activator; potassium channel activator | Details | |
| C04257 | BRD-K69885552 | pinanediol | Details | |||
| C04258 | BRD-A70998768 | pinaverium | CACNA1C | T-type calcium channel blocker | Details | |
| C04259 | BRD-K90727284 | pincainide | antiarrhythmic | Details | ||
| C04260 | BRD-A97701745 | pindolol | ADRB1|ADRB2|HTR1A|HTR1B|HTR2A|HTR2B | adrenergic receptor antagonist | Details | |
| C04261 | BRD-K95598440 | pindolol-(-) | HTR1A | adrenergic receptor antagonist; serotonin receptor antagonist | Details | |
| C04262 | BRD-A69275535 | pinitol | gamma secretase inhibitor | Details | ||
| C04263 | BRD-K94689771 | pinocembrin | CYP1B1 | cytochrome P450 inhibitor | Details | |
| C04264 | BRD-A48430263 | pioglitazone | PPARG|TRPM3 | insulin sensitizer; PPAR receptor agonist | Details | |
| C04265 | BRD-K26801045 | pipamperone | DRD2|HRH1|HTR1A|HTR1B|HTR1D|HTR2A | dopamine receptor antagonist | Details | |
| C04266 | BRD-A21544762 | pipecuronium | CHRM2|CHRM3|CHRNA2 | neuromuscular blocker | Details | |
| C04267 | BRD-K08999871 | pipemidic-acid | topoisomerase inhibitor | Details | ||
| C04268 | BRD-A53561827 | pipenzolate | CHRM1 | cholinergic receptor antagonist | Details | |
| C04269 | BRD-K16277217 | piperacetazine | dopamine receptor antagonist | Details | ||
| C04270 | BRD-K86873305 | piperacillin | bacterial cell wall synthesis inhibitor | Details | ||
| C04271 | BRD-K27382019 | piperaquine-phosphate | antimalarial agent | Details | ||
| C04272 | BRD-K13249881 | piperazine | GABRB3 | benzodiazepine receptor agonist | Details | |
| C04273 | BRD-K95941975 | piperazinedione | DNA synthesis inhibitor | Details | ||
| C04274 | BRD-A97479839 | piperidolate | CHRM1 | acetylcholine receptor antagonist | Details | |
| C04275 | BRD-K59522102 | piperine | MAOA|MAOB|TRPV1 | monoamine oxidase inhibitor | Details | |
| C04276 | BRD-K76452401 | piperonyl-butoxide | cytochrome P450 inhibitor | Details | ||
| C04277 | BRD-K15656090 | pipobroman | DNA alkylating agent | Details | ||
| C04278 | BRD-K48429278 | pipotiazine-palmitate | DRD1|DRD2|HTR1A|HTR2A | dopamine receptor antagonist; serotonin receptor antagonist | Details | |
| C04279 | BRD-K19456237 | piracetam | GRIA1|GRIA2|GRIA3|GRIA4 | acetylcholine receptor agonist | Details | |
| C04280 | BRD-K83794624 | pirarubicin | TOP2A | topoisomerase inhibitor | Details | |
| C04281 | BRD-K65992024 | pirenoxine | AGE inhibitor | Details | ||
| C04282 | BRD-K25224017 | pirenperone | HTR2A|HTR7 | serotonin receptor antagonist | Details | |
| C04283 | BRD-K89375097 | pirenzepine | CHRM1|CHRM2|CHRM3|CHRM4|CHRM5 | acetylcholine receptor antagonist | Details | |
| C04284 | BRD-K87990216 | piretanide | SLC12A1|SLC12A2 | glucocorticoid receptor agonist | Details | |
| C04285 | BRD-K96862998 | pirfenidone | FURIN|TNF | TGF beta receptor inhibitor | Details | |
| C04286 | BRD-K47936004 | piribedil | ADRA1A|ADRA2A|ADRA2C|DRD2|DRD3|DRD4|HTR1A|HTR2B | dopamine receptor agonist | Details | |
| C04287 | BRD-A04203391 | piricapiron | HTR2A | dopamine receptor antagonist; serotonin receptor antagonist | Details | |
| C04288 | BRD-K01902415 | pirinixic-acid | PPARA | PPAR receptor agonist | Details | |
| C04289 | BRD-A54490543 | pirlindole | MAOA | monoamine oxidase inhibitor | Details | |
| C04290 | BRD-A96510685 | piroctone-olamine | Details | |||
| C04291 | BRD-K22261391 | pirodavir | Details | |||
| C04292 | BRD-K37682401 | piromidic-acid | bacterial DNA gyrase inhibitor | Details | ||
| C04293 | BRD-A57382968 | piroxicam | PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C04294 | BRD-K71977764 | piroximone | PDE3A | phosphodiesterase inhibitor | Details | |
| C04295 | BRD-K63651590 | pirquinozol | histamine release inhibitor | Details | ||
| C04296 | BRD-K43978949 | PIT | P2RY1 | purinergic receptor antagonist | Details | |
| C04297 | BRD-K75958547 | pitavastatin | HMGCR | HMGCR inhibitor | Details | |
| C04298 | BRD-K62264492 | pivagabine | CRHR1|CRHR2 | corticosteroid releasing factor receptor antagonist | Details | |
| C04299 | BRD-K32791151 | pivampicillin | bacterial cell wall synthesis inhibitor | Details | ||
| C04300 | BRD-K20504455 | pivanex | HDAC1|HDAC2|HDAC3|HDAC8 | HDAC inhibitor | Details |