CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C01201 | BRD-K83335125 | chloroxoquinoline | Details | |||
| C01202 | BRD-K17223896 | chloroxylenol | ATP synthase inhibitor | Details | ||
| C01203 | BRD-A04553218 | chlorphenamine | HRH1|SLC6A2|SLC6A3|SLC6A4 | histamine receptor antagonist | Details | |
| C01204 | BRD-A92262698 | chlorphenesin | muscle relaxant | Details | ||
| C01205 | BRD-A39230911 | chlorphensin-carbamate | muscle relaxant | Details | ||
| C01206 | BRD-K25494650 | chlorproguanil | DHFR | dihydrofolate reductase inhibitor | Details | |
| C01207 | BRD-K89997465 | chlorpromazine | ADRA1A|ADRA1B|ADRA1D|ADRA2A|ADRA2B|ADRA2C|CALM1|CHRM1|CHRM3|DRD1|DRD2|DRD3|DRD4|DRD5|HRH1|HRH4|HTR1A|HTR2A|HTR2B|HTR2C|HTR6|HTR7|KCNH2|ORM1|ORM2|SMPD1|TRPC5 | dopamine receptor antagonist | Details | |
| C01208 | BRD-K97746869 | chlorpropamide | ABCC8|KCNJ10|KCNJ11 | ATP channel blocker | Details | |
| C01209 | BRD-K59590127 | chlorpropham | antiviral | Details | ||
| C01210 | BRD-K36207157 | chlorprothixene | CHRM1|CHRM2|CHRM3|CHRM4|CHRM5|DRD1|DRD2|DRD3|HRH1|HTR2A|HTR2B|HTR2C | dopamine receptor antagonist | Details | |
| C01211 | BRD-K08303368 | chlorpyrifos | ACHE | acetylcholinesterase inhibitor | Details | |
| C01212 | BRD-K90374350 | chlorquinaldol | other antibiotic | Details | ||
| C01213 | BRD-A25492003 | chlortetracycline | protein synthesis inhibitor | Details | ||
| C01214 | BRD-A26384407 | chlorthalidone | CA1|CA12|CA14|CA4|CA7|SLC12A1|SLC12A3 | carbonic anhydrase inhibitor | Details | |
| C01215 | BRD-K98174813 | chlorzoxazone | KCNMA1|KCNN4 | bacterial 30S ribosomal subunit inhibitor | Details | |
| C01216 | BRD-K62779383 | cholecalciferol | VDR | Details | ||
| C01217 | BRD-A42883684 | cholesterol | RORA | Details | ||
| C01218 | BRD-K43164539 | cholic-acid | ADH1C|CES1|COX4I1|COX5A|COX5B|COX6A2|COX6B1|COX6C|COX7A1|COX7B|COX7C|COX8A|ESRRG|FABP6|FECH|GPBAR1|MT-CO1|MT-CO2|MT-CO3|PLA2G1B | bile acid | Details | |
| C01219 | BRD-K77300776 | choline | ACHE|BCHE|CHRNA2|PCYT1A|PCYT1B|PHOSPHO1|PLD1|PLD2 | acetylcholine precursor | Details | |
| C01220 | BRD-A72390365 | choline-alfoscerate | GM2A | acetylcholine precursor | Details | |
| C01221 | BRD-A19381518 | CHPG | GRM5 | glutamate receptor agonist | Details | |
| C01222 | BRD-K76259716 | CHR-6494 | GSG2 | serine/threonine kinase inhibitor | Details | |
| C01223 | BRD-M02075109 | chromanol-(+/-) | potassium channel blocker | Details | ||
| C01224 | BRD-K27911943 | chromanol-293B-(-)-[3R,4S] | potassium channel blocker | Details | ||
| C01225 | BRD-K94720315 | chromocarb | antispasmodic | Details | ||
| C01226 | BRD-K22861715 | chrysin | AKR1B1|CDK6|CYP19A1|CYP1B1 | breast cancer resistance protein inhibitor | Details | |
| C01227 | BRD-K59284035 | chrysophanic-acid | EGFR|MTOR | EGFR inhibitor | Details | |
| C01228 | BRD-K25691735 | chuanxiongzine | Details | |||
| C01229 | BRD-K22314899 | CH223191 | AHR | aryl hydrocarbon receptor antagonist | Details | |
| C01230 | BRD-K28352084 | CH5132799 | MTOR|PIK3CA|PIK3CB|PIK3CD|PIK3CG | PI3K inhibitor | Details | |
| C01231 | BRD-K71487808 | CH55 | RARA|RARB | retinoid receptor binder | Details | |
| C01232 | BRD-K83022601 | CI-844 | Details | |||
| C01233 | BRD-A50016482 | CI-923 | acetylcholine receptor antagonist | Details | ||
| C01234 | BRD-K67680372 | CI-966 | SLC6A1 | GAT inhibitor | Details | |
| C01235 | BRD-K88544581 | CI-976 | ACAT1|CES1 | ACAT inhibitor | Details | |
| C01236 | BRD-K01423020 | ciaftalan-zinc | reactive oxygen species stimulant | Details | ||
| C01237 | BRD-K58736316 | cianidanol | PTGS1 | fatty acid synthase inhibitor | Details | |
| C01238 | BRD-K34251960 | cibenzoline | sodium channel blocker | Details | ||
| C01239 | BRD-K35245662 | ciclesonide | NR3C1|SERPINA6 | glucocorticoid receptor agonist | Details | |
| C01240 | BRD-K13044802 | ciclopirox | ATP1A1 | membrane integrity inhibitor | Details | |
| C01241 | BRD-A94965935 | cicloprofen | PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C01242 | BRD-A59391172 | CID-16020046 | GPR55 | G protein-coupled receptor antagonist | Details | |
| C01243 | BRD-K92781136 | CID-2011756 | PKD1 | protein kinase inhibitor | Details | |
| C01244 | BRD-K06405316 | CID-2745687 | GPR35 | G protein-coupled receptor antagonist | Details | |
| C01245 | BRD-A08840375 | CID-5458317 | MAPK3 | MAP kinase phosphatase inhibitor | Details | |
| C01246 | BRD-K96153583 | cidofovir | DNA polymerase inhibitor | Details | ||
| C01247 | BRD-A93000692 | ciglitazone | PPARG | PPAR receptor agonist | Details | |
| C01248 | BRD-K85518562 | cilastatin | DPEP1 | dehydropeptidase inhibitor | Details | |
| C01249 | BRD-K65518078 | cilazapril | ACE | angiotensin converting enzyme inhibitor | Details | |
| C01250 | BRD-K57252450 | cilengitide | ITGAV|ITGB3 | integrin antagonist | Details | |
| C01251 | BRD-A02743701 | cilnidipine | CACNA1B | calcium channel blocker | Details | |
| C01252 | BRD-K38473998 | cilomilast | PDE4A|PDE4B|PDE4D | phosphodiesterase inhibitor | Details | |
| C01253 | BRD-K28578425 | cilostamide | PDE3A|PDE3B | phosphodiesterase inhibitor | Details | |
| C01254 | BRD-K67017579 | cilostazol | PDE3A|PDE3B | phosphodiesterase inhibitor | Details | |
| C01255 | BRD-A75514485 | CIM-0216 | TRPM3 | transient receptor potential channel agonist | Details | |
| C01256 | BRD-A65440446 | cimaterol | ADRB1|ADRB2|ADRB3 | adrenergic receptor agonist | Details | |
| C01257 | BRD-K34157611 | cimetidine | HRH2|SLC29A4|SLC47A1|SLC47A2 | histamine receptor antagonist | Details | |
| C01258 | BRD-A99899486 | cimetropium | CHRM1 | acetylcholine receptor antagonist | Details | |
| C01259 | BRD-K73838513 | cinacalcet | CASR | calcium channel activator | Details | |
| C01260 | BRD-K73440166 | cinaciguat | GUCY1A3|GUCY1B3 | guanylate cyclase activator | Details | |
| C01261 | BRD-K53720352 | cinalukast | CYSLTR1 | leukotriene receptor antagonist | Details | |
| C01262 | BRD-K40901640 | cinanserin | HTR2A | serotonin receptor antagonist | Details | |
| C01263 | BRD-K99121711 | cinchocaine | CALM1|SCN10A|SCN5A | sodium channel blocker | Details | |
| C01264 | BRD-K39079086 | cinchonidine | P glycoprotein inhibitor | Details | ||
| C01265 | BRD-K14693417 | cinchonine | CYP2D6 | P glycoprotein inhibitor | Details | |
| C01266 | BRD-K72915123 | cinchophen | analgesic agent | Details | ||
| C01267 | BRD-K00531707 | cinepazet | vasodilator | Details | ||
| C01268 | BRD-K46839850 | cinepazide | calcium channel activator | Details | ||
| C01269 | BRD-K25154476 | cinflumide | muscle relaxant | Details | ||
| C01270 | BRD-K38088841 | cinnamaldehyde | TRPA1 | aldose reductase inhibitor; TRPV agonist | Details | |
| C01271 | BRD-K07220430 | cinnarazine | calcium channel blocker | Details | ||
| C01272 | BRD-K08699567 | cinoctramide | Details | |||
| C01273 | BRD-K14704277 | cinoxacin | topoisomerase inhibitor | Details | ||
| C01274 | BRD-K17828029 | cinoxate | Details | |||
| C01275 | BRD-K24570280 | CINPA-1 | NR1H4|NR1I3|PPARG | CAR antagonist | Details | |
| C01276 | BRD-K66241279 | cinromide | Details | |||
| C01277 | BRD-K24507548 | cintriamide | Details | |||
| C01278 | BRD-K95362002 | cipemastat | ADAM17|MMP1|MMP13|MMP2|MMP3|MMP8|MMP9 | metalloproteinase inhibitor | Details | |
| C01279 | BRD-A49358627 | ciprofibrate | PPARA | PPAR receptor agonist | Details | |
| C01280 | BRD-K04804440 | ciprofloxacin | TOP2A | bacterial DNA gyrase inhibitor | Details | |
| C01281 | BRD-K01767299 | ciproxifan | ADRA2A|ADRA2C|HRH3|HRH4|HTR3A | histamine receptor antagonist | Details | |
| C01282 | BRD-A35425966 | CIQ | GRIN2C|GRIN2D | glutamate receptor potentiator | Details | |
| C01283 | BRD-K54142781 | cirazoline | ADRA1A | adrenergic receptor agonist | Details | |
| C01284 | BRD-K71756122 | cis-aconitic-acid | ACO2 | Details | ||
| C01285 | BRD-M29936662 | cis-ACPD | GRM2|GRM3|GRM6|GRM7|GRM8 | glutamate receptor agonist | Details | |
| C01286 | BRD-K41962502 | cis-exo-camphanediol-2,3 | NOS3 | nitric oxide stimulant | Details | |
| C01287 | BRD-K25146005 | cis-urocanic acid | HTR2A | serotonin receptor agonist | Details | |
| C01288 | BRD-K52670952 | cis-urocanic-acid | HTR2A | serotonin receptor agonist | Details | |
| C01289 | BRD-K80025777 | cis-9,trans-11-Conjugated-linoleic-acid | Details | |||
| C01290 | BRD-A12896037 | cisapride | HTR2A|HTR3A|HTR4|KCNH2 | serotonin receptor agonist | Details | |
| C01291 | BRD-K17498618 | cisatracurium | CHRNA2 | acetylcholine receptor antagonist | Details | |
| C01292 | BRD-K69172251 | cisplatin | XIAP | DNA alkylating agent; DNA synthesis inhibitor | Details | |
| C01293 | BRD-A47598013 | citalopram | SLC6A2|SLC6A4 | selective serotonin reuptake inhibitor (SSRI) | Details | |
| C01294 | BRD-K53263234 | CITCO | NR1I3 | constitutive androstane receptor (CAR) agonist | Details | |
| C01295 | BRD-A91728607 | citicoline | ACHE|SLC1A2 | membrane permeability enhancer; glutathione transferase stimulant | Details | |
| C01296 | BRD-A57957888 | citiolone | lipotropic; mucolytic agent | Details | ||
| C01297 | BRD-K76792669 | citric-acid | AKR1B1|ANG|APRT|BHMT|C8G|CA4|CPB1|CS|CTDSP1|GNMT|HGS|HS3ST3A1|IL4I1|ITPA|LSM6|MDH2|MIF|PDE5A|PKD2L1|PLEKHA1|RNASE1|RNASE3|SRC|TNFSF13B|UCK2 | coagulation factor inhibitor | Details | |
| C01298 | BRD-K21306330 | CJ-033466 | HTR4 | serotonin receptor agonist | Details | |
| C01299 | BRD-K81572616 | CK-636 | ACTR2|ACTR3|ARPC1B|ARPC2|ARPC3|ARPC4|ARPC5 | actin related protein inhibitor | Details | |
| C01300 | BRD-A26458246 | CKD-712 | JAK2|STAT1 | NFkB pathway inhibitor | Details |