CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
stats1
stats2
6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C00201 | BRD-K84810405 | almorexant | HCRTR1|HCRTR2 | orexin receptor antagonist | Details | |
| C00202 | BRD-K67601717 | almotriptan | HTR1B|HTR1D | serotonin receptor agonist | Details | |
| C00203 | BRD-K04851519 | aloe-emodin | CASP8 | anticancer agent | Details | |
| C00204 | BRD-A27084604 | alogliptin | DPP4 | dipeptidyl peptidase inhibitor | Details | |
| C00205 | BRD-K02074536 | aloin | angiogenesis inhibitor | Details | ||
| C00206 | BRD-K96391852 | aloperine | Details | |||
| C00207 | BRD-K46742498 | alosetron | HTR3A | serotonin receptor antagonist | Details | |
| C00208 | BRD-K91188791 | aloxistatin | CTSG | protease inhibitor | Details | |
| C00209 | BRD-K54997624 | alpelisib | PIK3CA|PIK3CB|PIK3CD|PIK3CG | PI3K inhibitor | Details | |
| C00210 | BRD-K72536715 | alpha-Asarone | HMGCR | cytochrome P450 inhibitor; HMGCR inhibitor | Details | |
| C00211 | BRD-K87424134 | alpha-D-glucopyranose | Details | |||
| C00212 | BRD-K33396764 | alpha-linolenic-acid | ELOVL4|FADS1|FADS2|FFAR1|FFAR4|PTGS2|SLC8A1|TRPV1 | omega 3 fatty acid stimulant | Details | |
| C00213 | BRD-K80028314 | alpha-methylhistamine-dihydrobromide-(R)-(-) | HRH3 | histamine receptor agonist | Details | |
| C00214 | BRD-K28308851 | alpha-methylhistamine-dihydrobromide-(S)-(+) | HRH3 | histamine receptor agonist | Details | |
| C00215 | BRD-A17745711 | alpha-methylserotonin | HTR1D|HTR1E|HTR1F|HTR2A|HTR2B|HTR2C|HTR4 | serotonin receptor agonist | Details | |
| C00216 | BRD-A82892199 | alpha-tochopherol | antioxidant | Details | ||
| C00217 | BRD-A61850409 | alpha-tochopheryl-acetate | antioxidant | Details | ||
| C00218 | BRD-K66896751 | alpidem | GABRA1 | benzodiazepine receptor agonist | Details | |
| C00219 | BRD-A00993607 | alprenolol | ADRB1|ADRB2|HTR1A | adrenergic receptor antagonist | Details | |
| C00220 | BRD-K52459643 | alprostadil | CATSPER1|CATSPER2|CATSPER3|CATSPER4|PTGDR|PTGER1|PTGER2|PTGER4|PTGIR | prostanoid receptor agonist | Details | |
| C00221 | BRD-K35498378 | alrestatin | AKR1B1 | aldose reductase inhibitor | Details | |
| C00222 | BRD-K21415491 | ALS-8176 | RNA polymerase inhibitor | Details | ||
| C00223 | BRD-K00610438 | altanserin | HTR2A | serotonin receptor antagonist | Details | |
| C00224 | BRD-A56675431 | althiazide | diuretic | Details | ||
| C00225 | BRD-K52681925 | altinicline | CHRNA4|CHRNB2 | nicotinic receptor agonist | Details | |
| C00226 | BRD-K78627070 | altiratinib | KDR|MET|TEK | VEGFR inhibitor; MET inhibitor | Details | |
| C00227 | BRD-K14619660 | altrenogest | PGR | progestogen hormone | Details | |
| C00228 | BRD-K67043667 | altretamine | DNA synthesis inhibitor | Details | ||
| C00229 | BRD-K89055274 | alverine | HTR1A | muscle relaxant | Details | |
| C00230 | BRD-K83988098 | alvespimycin | HSP90AA1 | HSP inhibitor | Details | |
| C00231 | BRD-K07857022 | alvimopan | OPRD1|OPRK1|OPRM1 | opioid receptor antagonist | Details | |
| C00232 | BRD-K87909389 | alvocidib | CDK1|CDK2|CDK4|CDK5|CDK6|CDK7|CDK8|CDK9|EGFR|PYGM | CDK inhibitor | Details | |
| C00233 | BRD-K53979406 | ALX-5407 | SLC6A9 | Glycine transporter 1 inhibitor | Details | |
| C00234 | BRD-A66116161 | AM-1241 | CNR1|CNR2 | cannabinoid receptor agonist | Details | |
| C00235 | BRD-K59013864 | AM-24 | ALOX5 | lipoxygenase inhibitor | Details | |
| C00236 | BRD-K92000912 | AM-251 | CNR1|GPR18|GPR55 | cannabinoid receptor antagonist | Details | |
| C00237 | BRD-K59419204 | AM-281 | CNR1|CNR2|GPR55 | cannabinoid receptor antagonist | Details | |
| C00238 | BRD-K55462201 | AM-404 | CNR1|CNR2|FAAH|TRPV1 | cyclooxygenase inhibitor; FAAH inhibitor; TRPV antagonist | Details | |
| C00239 | BRD-K06854232 | AM-580 | RARA | retinoid receptor agonist | Details | |
| C00240 | BRD-K63533170 | AM-630 | CNR1|CNR2 | cannabinoid receptor antagonist | Details | |
| C00241 | BRD-A11813248 | AM-92016 | GRIN1 | potassium channel blocker | Details | |
| C00242 | BRD-K70330367 | amantadine | DRD2|GRIN2A|GRIN2B|GRIN2C|GRIN2D|GRIN3A | glutamate receptor antagonist | Details | |
| C00243 | BRD-K11244467 | ambazone | DNA damage inducer | Details | ||
| C00244 | BRD-K11292736 | ambenonium | ACHE | cholinesterase inhibitor | Details | |
| C00245 | BRD-K41185545 | ambrisentan | EDNRA|EDNRB | endothelin receptor antagonist | Details | |
| C00246 | BRD-K56558538 | ambroxol | CYP3A4 | sodium channel blocker | Details | |
| C00247 | BRD-A36010170 | amcinonide | ANXA1|NR3C1 | glucocorticoid receptor agonist | Details | |
| C00248 | BRD-K03019184 | AMD-3465 | CXCR4 | CC chemokine receptor antagonist | Details | |
| C00249 | BRD-K41051431 | amdinocillin | bacterial cell wall synthesis inhibitor | Details | ||
| C00250 | BRD-K42948882 | AMD11070 | CXCR4 | CC chemokine receptor antagonist | Details | |
| C00251 | BRD-K48173020 | ameltolide | anticonvulsant | Details | ||
| C00252 | BRD-K51387999 | amezinium | ADRB2 | adrenergic receptor agonist | Details | |
| C00253 | BRD-K82122102 | amfenac | PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C00254 | BRD-A37288617 | amfepramone | SLC6A2|SLC6A3 | adrenergic receptor agonist | Details | |
| C00255 | BRD-K50813454 | amflutizole | XDH | xanthine oxidase inhibitor | Details | |
| C00256 | BRD-K04374714 | AMG-PERK-44 | EIF2AK4 | PERK inhibitor | Details | |
| C00257 | BRD-K32285926 | AMG-208 | MET | tyrosine kinase inhibitor | Details | |
| C00258 | BRD-K64925568 | AMG-232 | MDM2 | MDM inhibitor | Details | |
| C00259 | BRD-K21077415 | AMG-319 | PIK3CD | PI3K inhibitor | Details | |
| C00260 | BRD-K27061362 | AMG-337 | MET | MET inhibitor | Details | |
| C00261 | BRD-K90239174 | AMG-487 | CC chemokine receptor antagonist | Details | ||
| C00262 | BRD-A01307728 | AMG-487-(+/-) | CXCR3 | CC chemokine receptor antagonist | Details | |
| C00263 | BRD-K34185671 | AMG-517 | TRPV1 | TRPV antagonist | Details | |
| C00264 | BRD-K86673452 | AMG-548 | MAPK11|MAPK12|MAPK13|MAPK14 | MAP kinase inhibitor | Details | |
| C00265 | BRD-K43802723 | AMG-837 | FFAR1 | free fatty acid receptor agonist | Details | |
| C00266 | BRD-K97452254 | AMG-925 | CDK4|CDK6|FLT3 | CDK inhibitor; FLT3 inhibitor | Details | |
| C00267 | BRD-K01995783 | AMG-9810 | TRPV1 | TRPV antagonist | Details | |
| C00268 | BRD-A58947127 | AMG319 | PIK3CD | PI3K inhibitor | Details | |
| C00269 | BRD-K21782625 | AMG458 | MET | MET inhibitor | Details | |
| C00270 | BRD-K21728777 | AMG900 | AURKA|AURKB|AURKC | Aurora kinase inhibitor | Details | |
| C00271 | BRD-K75114721 | AMI-1 | PRMT1 | protein arginine N-methyltransferase inhibitor | Details | |
| C00272 | BRD-K24610819 | amibegron | ADRB3 | adrenergic receptor agonist | Details | |
| C00273 | BRD-K12568846 | amidopyrine | analgesic agent | Details | ||
| C00274 | BRD-K80262108 | amifampridine | potassium channel blocker | Details | ||
| C00275 | BRD-A19401019 | amiflamine | MAOA|SLC6A2 | monoamine oxidase inhibitor | Details | |
| C00276 | BRD-K73947551 | amifostine | ALPPL2|ENPP1 | reducing agent | Details | |
| C00277 | BRD-A01603276 | amikacin | bacterial 30S ribosomal subunit inhibitor | Details | ||
| C00278 | BRD-K97181089 | amiloride | AOC1|ASIC1|ASIC2|ASIC3|PKD2|PKD2L1|PLAU|SCNN1A|SCNN1B|SCNN1D|SCNN1G|SLC9A1|TRPC7|TRPV2 | sodium channel blocker | Details | |
| C00279 | BRD-K24219278 | amineptine | SLC6A2|SLC6A4 | dopamine receptor agonist | Details | |
| C00280 | BRD-K64931368 | aminocaproic-acid | LPA|PLAT|PLG | plasminogen activator inhibitor | Details | |
| C00281 | BRD-A25234499 | aminoglutethimide | CYP11A1|CYP19A1 | glucocorticoid receptor antagonist | Details | |
| C00282 | BRD-K25114078 | aminoguanidine | NOS2 | nitric oxide synthase inhibitor | Details | |
| C00283 | BRD-A40777960 | aminohydroxybutyric-acid | Details | |||
| C00284 | BRD-K59998349 | aminolevulinic-acid-benzyl-ester | Details | |||
| C00285 | BRD-A28318179 | aminomethyltransferase | NOS2 | nitric oxide synthase inhibitor | Details | |
| C00286 | BRD-A69917777 | aminopentamide | CHRM1 | acetylcholine receptor antagonist | Details | |
| C00287 | BRD-K97799481 | aminophylline | ADORA1|ADORA2A|ADORA2B|ADORA3|HDAC2|PDE3A|PDE3B|PDE4A|PDE4B|PDE4C|PDE4D | adenosine receptor antagonist | Details | |
| C00288 | BRD-K87544030 | aminopterin | DHFR|SLC46A1 | dihydrofolate reductase inhibitor | Details | |
| C00289 | BRD-K07762753 | aminopurvalanol-a | CDK1|CDK2|CDK5|CDK6 | CDK inhibitor; tyrosine kinase inhibitor | Details | |
| C00290 | BRD-K80267133 | aminosalicylate | ALOX5|CHUK|PLA2G2E|PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C00291 | BRD-K94837153 | aminothiadiazole | ADORA3|IMPDH1 | inosine monophosphate dehydrogenase inhibitor | Details | |
| C00292 | BRD-K13421763 | aminothiazole | NOS2 | cyclin D inhibitor | Details | |
| C00293 | BRD-K17561142 | amiodarone | ADRB1|CACNA1H|CACNA2D2|KCNA7|KCNH2 | potassium channel blocker | Details | |
| C00294 | BRD-K97643133 | amiprilose | CD antagonist | Details | ||
| C00295 | BRD-A60197193 | amisulpride | DRD2|DRD3|HTR2A|HTR7 | dopamine receptor antagonist | Details | |
| C00296 | BRD-A68942014 | amitifadine | SLC6A2|SLC6A3|SLC6A4 | serotonin transporter (SERT) inhibitor | Details | |
| C00297 | BRD-K33335792 | amitraz | ADRA1A|ADRA2A | adrenergic receptor agonist | Details | |
| C00298 | BRD-K53737926 | amitriptyline | ADRA1A|ADRA1B|ADRA1D|ADRA2A|ADRB1|ADRB2|ADRB3|CHRM1|CHRM2|CHRM3|CHRM4|CHRM5|HRH1|HRH2|HRH4|HTR1A|HTR1B|HTR1D|HTR2A|HTR2C|HTR6|HTR7|KCNA1|KCND2|KCND3|KCNQ2|KCNQ3|NTRK1|NTRK2|OPRD1|OPRK1|OPRM1|SIGMAR1|SLC6A2|SLC6A4 | norepinephrine inhibitor; norepinephrine reuptake inhibitor; serotonin receptor antagonist; serotonin norepinephrine reuptake inhibitor (SNRI) | Details | |
| C00299 | BRD-K29530284 | amlexanox | FGF1|IL3|PDE4A|PDE4B|PDE4C|PDE4D|S100A12|S100A13 | histamine receptor modulator | Details | |
| C00300 | BRD-A22032524 | amlodipine | CA1|CACNA1B|CACNA1C|CACNA1D|CACNA1F|CACNA1S|CACNA2D1|CACNA2D3|CACNB1|CACNB2|SMPD1 | calcium channel blocker | Details |