CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C03601 | BRD-A01787639 | naftopidil | ADRA1A | adrenergic receptor antagonist | Details | |
| C03602 | BRD-K66404838 | nalbuphine | OPRD1|OPRK1|OPRM1 | opioid receptor agonist; opioid receptor antagonist | Details | |
| C03603 | BRD-K89272869 | nalfurafine | OPRK1|OPRM1 | opioid receptor agonist | Details | |
| C03604 | BRD-K47886988 | nalidixic-acid | bacterial DNA gyrase inhibitor | Details | ||
| C03605 | BRD-K68407436 | nalmefene | OPRD1|OPRK1|OPRM1 | opioid receptor antagonist | Details | |
| C03606 | BRD-K41458421 | naloxegol | OPRM1 | opioid receptor antagonist | Details | |
| C03607 | BRD-K67511046 | naloxone | CREB1|ESR1|OPRD1|OPRK1|OPRM1|TLR4 | opioid receptor antagonist | Details | |
| C03608 | BRD-K70898774 | naloxone-benzoylhydrazone | OPRK1|OPRM1 | opioid receptor antagonist | Details | |
| C03609 | BRD-K88172511 | naltrexone | OPRD1|OPRK1|OPRM1|SIGMAR1 | opioid receptor antagonist | Details | |
| C03610 | BRD-A19102171 | naltriben | OPRD1|OPRK1|OPRM1 | opioid receptor antagonist | Details | |
| C03611 | BRD-A47342814 | naltrindole | OPRD1|OPRK1|OPRM1 | opioid receptor antagonist | Details | |
| C03612 | BRD-K18280217 | Nampt-IN-1 | Details | |||
| C03613 | BRD-K69195780 | NAN-190 | ADRA1A|ADRA1B|ADRA1D|HTR1A|HTR1F | serotonin receptor agonist | Details | |
| C03614 | BRD-A73871920 | nanchangmycin | other antibiotic | Details | ||
| C03615 | BRD-K52080565 | nandrolone | AR|CYP19A1|MAOA|MAOB | imidazoline receptor agonist | Details | |
| C03616 | BRD-K78352627 | nandrolone-decanoate | AR | androgenic steroid | Details | |
| C03617 | BRD-K22064724 | napabucasin | STAT3 | STAT inhibitor | Details | |
| C03618 | BRD-K77641333 | naphazoline | ADRA1A|ADRA2A | adrenergic receptor agonist | Details | |
| C03619 | BRD-K13664493 | naphthoquine-phosphate | antimalarial agent | Details | ||
| C03620 | BRD-K91234829 | napirimus | immunosuppressant | Details | ||
| C03621 | BRD-K59197931 | naproxen | PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C03622 | BRD-A25608658 | narasin | antiprotozoal agent | Details | ||
| C03623 | BRD-K61337602 | naratriptan | HTR1A|HTR1B|HTR1D|HTR1E|HTR1F | serotonin receptor agonist | Details | |
| C03624 | BRD-K08832567 | naringenin | CYP19A1|CYP1B1|ESR2|GLO1|HSD17B1 | aromatase inhibitor; TRPV antagonist | Details | |
| C03625 | BRD-K87122641 | naringeninic-acid | HCAR2|PTGR1 | Details | ||
| C03626 | BRD-K02953697 | naringin | SLCO1A2 | cytochrome P450 inhibitor | Details | |
| C03627 | BRD-K13511380 | naringin-dihydrochalcone | cytochrome P450 inhibitor | Details | ||
| C03628 | BRD-K38287497 | narlaprevir | HCV inhibitor | Details | ||
| C03629 | BRD-K17295893 | nastorazepide | CCKBR | CCK receptor antagonist | Details | |
| C03630 | BRD-K90563805 | natamycin | fungal ergosterol inhibitor | Details | ||
| C03631 | BRD-K44353683 | nateglinide | ABCC8|KCNJ10|KCNJ11|PPARG | insulin secretagogue | Details | |
| C03632 | BRD-A84202322 | NAV-26 | SCN9A | voltage-gated sodium channel blocker | Details | |
| C03633 | BRD-K82850175 | navarixin | CXCR1|CXCR2 | CC chemokine receptor antagonist | Details | |
| C03634 | BRD-K82746043 | navitoclax | BCL2|BCL2L1|BCL2L2 | BCL inhibitor | Details | |
| C03635 | BRD-K61177364 | NBI-27914 | CRHR1 | corticosteroid releasing factor receptor antagonist | Details | |
| C03636 | BRD-A86523169 | NBI-74330-(+/-) | CXCR3 | CC chemokine receptor antagonist | Details | |
| C03637 | BRD-K11796549 | NBQX | GRIA1|GRIA2|GRIA3|GRIA4|GRIK1|GRIN1|GRIN2A|GRIN2B | glutamate receptor antagonist | Details | |
| C03638 | BRD-A85025557 | NCS-382 | GABBR1|GABBR2|SLC52A2 | GABA receptor antagonist | Details | |
| C03639 | BRD-K17539220 | NDT-9513727 | C5AR1 | complement antagonist | Details | |
| C03640 | BRD-K11443721 | NE-100 | SIGMAR1 | sigma receptor antagonist | Details | |
| C03641 | BRD-K04956647 | nebivolol | ADRB1|ADRB2 | adrenergic receptor antagonist | Details | |
| C03642 | BRD-A51355958 | nebracetam | CHRM1 | acetylcholine receptor agonist | Details | |
| C03643 | BRD-K14395568 | NECA | ADORA1|ADORA2A|ADORA2B|ADORA3|HSP90B1 | adenosine receptor agonist | Details | |
| C03644 | BRD-A36318220 | necrostatin-1 | RIPK1 | RIPK inhibitor | Details | |
| C03645 | BRD-K68851986 | necrostatin-2 | RIPK2 | necroptosis inhibitor; RIPK inhibitor | Details | |
| C03646 | BRD-K38820178 | nedaplatin | DNA inhibitor | Details | ||
| C03647 | BRD-K64716392 | nedocromil | CYSLTR1|CYSLTR2|FPR1|HSP90AA1|PTGDR | histamine receptor antagonist | Details | |
| C03648 | BRD-K90789829 | nefazodone | ADRA1A|ADRA1B|ADRA2A|CYP3A4|HTR1A|HTR2A|HTR2C|SLC6A2|SLC6A3|SLC6A4 | adrenergic inhibitor; norepinephrine reuptake inhibitor; serotonin receptor antagonist; serotonin reuptake inhibitor | Details | |
| C03649 | BRD-K65678996 | nefiracetam | CHRM1 | acetylcholine receptor agonist; benzodiazepine receptor agonist | Details | |
| C03650 | BRD-A78877355 | nefopam | cyclooxygenase inhibitor | Details | ||
| C03651 | BRD-K84466663 | nelarabine | POLA1 | DNA synthesis inhibitor; T cell inhibitor | Details | |
| C03652 | BRD-K74117820 | nelfinavir | CYP1A2|CYP2B6|CYP2C19|CYP2C9|CYP2D6|CYP3A4|CYP3A7 | HIV protease inhibitor | Details | |
| C03653 | BRD-M80207679 | nemonapride | DRD2|DRD3|DRD4 | dopamine receptor antagonist | Details | |
| C03654 | BRD-K51911221 | nemorubicin | TOP1|TOP2A | topoisomerase inhibitor | Details | |
| C03655 | BRD-A53539450 | neo-gilurytmal | Details | |||
| C03656 | BRD-K96299080 | neohesperidin | Details | |||
| C03657 | BRD-K61032563 | neohesperidin-dihydrochalcone | Details | |||
| C03658 | BRD-K71013094 | neomycin | CXCR4 | bacterial 30S ribosomal subunit inhibitor | Details | |
| C03659 | BRD-K71013094 | neomycin-sulfate | bacterial 30S ribosomal subunit inhibitor | Details | ||
| C03660 | BRD-K18922609 | neostigmine | ACHE | acetylcholinesterase inhibitor | Details | |
| C03661 | BRD-K04112579 | nepafenac | PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C03662 | BRD-K09126848 | nepicastat | DBH | dopamine beta hydroxylase inhibitor | Details | |
| C03663 | BRD-K85606544 | neratinib | EGFR|ERBB2|KDR | EGFR inhibitor | Details | |
| C03664 | BRD-K43647122 | nerbacadol | cyclooxygenase inhibitor | Details | ||
| C03665 | BRD-K60212747 | neridronic-acid | FDPS | bone resorption inhibitor | Details | |
| C03666 | BRD-K79989959 | nesbuvir | RNA polymerase inhibitor | Details | ||
| C03667 | BRD-A59825838 | netilmicin | protein synthesis inhibitor | Details | ||
| C03668 | BRD-K97428065 | netupitant | TACR1 | tachykinin antagonist | Details | |
| C03669 | BRD-K22631935 | neurodazine | neurogenesis of non-pluripotent C2C12 myoblast inducer | Details | ||
| C03670 | BRD-K28567778 | neuropathiazol | BMP2|LIF | neural stem cell inducer | Details | |
| C03671 | BRD-K15502390 | nevirapine | CYP1A2|CYP2A6|CYP2B6|CYP2C9|CYP2D6|CYP3A4|CYP3A5 | non-nucleoside reverse transcriptase inhibitor | Details | |
| C03672 | BRD-K70402238 | nexturastat-a | HDAC1|HDAC6 | HDAC inhibitor | Details | |
| C03673 | BRD-K83354763 | NFKB-activation-inhibitor-II | RELA | NFkB pathway inhibitor | Details | |
| C03674 | BRD-K89223384 | NG-nitro-arginine | NOS1|NOS2|NOS3 | nitric oxide synthase inhibitor | Details | |
| C03675 | BRD-K05181084 | NGB-2904 | DRD3 | dopamine receptor antagonist | Details | |
| C03676 | BRD-K28639661 | NGD-94-1 | DRD4 | dopamine receptor antagonist | Details | |
| C03677 | BRD-K81779590 | NGD-98-2 | CRHR1 | corticosteroid releasing factor receptor antagonist | Details | |
| C03678 | BRD-K05653025 | NHI-2 | LDHA | lactate dehydrogenase inhibitor | Details | |
| C03679 | BRD-K31086665 | NH125 | eukaryotic translation elongation factor 2 inhibitor | Details | ||
| C03680 | BRD-K03042257 | NI-57 | BRD1|BRPF1|BRPF3 | bromodomain inhibitor | Details | |
| C03681 | BRD-K60237333 | niacin | DGAT2|HCAR1|HCAR2|HCAR3|NNMT|QPRT | NAD precursor; vitamin B | Details | |
| C03682 | BRD-K12102668 | nialamide | COMT|MAOA|MAOB | monoamine oxidase inhibitor | Details | |
| C03683 | BRD-A85876464 | nibentan | potassium channel blocker | Details | ||
| C03684 | BRD-A86871940 | nicaraven | free radical scavenger | Details | ||
| C03685 | BRD-A26711594 | nicardipine | ADORA3|ADRA1A|ADRA1B|ADRA1D|CACNA1C|CACNA1D|CACNA2D1|CACNB2|CALM1|CHRM1|CHRM2|CHRM3|CHRM4|CHRM5|PDE1A|PDE1B | calcium channel blocker | Details | |
| C03686 | BRD-K76810206 | nicergoline | ADRA1A | adrenergic receptor antagonist | Details | |
| C03687 | BRD-K11256763 | niceritrol | NAD precursor | Details | ||
| C03688 | BRD-K35960502 | niclosamide | STAT3 | DNA replication inhibitor; STAT inhibitor | Details | |
| C03689 | BRD-K97752965 | nicorandil | KCNJ11 | nitric oxide donor; potassium channel activator | Details | |
| C03690 | BRD-K28912512 | nicotinamide | BST1|LDHA|PARP1|SIRT5 | protein synthesis stimulant | Details | |
| C03691 | BRD-A93695607 | nicotine | CHAT|CHRNA10|CHRNA2|CHRNA3|CHRNA4|CHRNA5|CHRNA6|CHRNA7|CHRNA9|CHRNB2|CHRNB3|CHRNB4|CYP19A1|TBXAS1|TRPA1 | acetylcholine receptor agonist | Details | |
| C03692 | BRD-K76600340 | nicotinyl-alcohol-tartrate | Details | |||
| C03693 | BRD-K17617556 | NIDA-41020 | CNR1 | cannabinoid receptor antagonist | Details | |
| C03694 | BRD-K96354014 | nifedipine | CACNA1C|CACNA1D|CACNA1F|CACNA1H|CACNA1S|CACNA2D1|CACNB2|CALM1|GLRA1|GLRA3|GLRB|KCNA1|KCNA5|NR1I2|TRPM3 | calcium channel blocker | Details | |
| C03695 | BRD-K32311154 | nifekalant | potassium channel blocker | Details | ||
| C03696 | BRD-A21280314 | nifenalol | ADRB1|ADRB2 | adrenergic receptor antagonist | Details | |
| C03697 | BRD-K47407372 | nifenazone | analgesic agent | Details | ||
| C03698 | BRD-K98763141 | niflumic-acid | ANO1|CLCN1|CLCNKA|CLCNKB|KCNQ1|PLA2G1B|PLA2G4A|PTGS1|PTGS2|UGT1A9 | cyclooxygenase inhibitor | Details | |
| C03699 | BRD-K68188368 | nifuroxazide | bacterial DNA inhibitor | Details | ||
| C03700 | BRD-K85757157 | nifursol | bacterial DNA inhibitor | Details |