CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C04101 | BRD-K41438959 | perampanel | GRIA1|GRIA2|GRIA3|GRIA4 | glutamate receptor antagonist | Details | |
| C04102 | BRD-K86435560 | perchlozone | Details | |||
| C04103 | BRD-K99431849 | peretinoin | RXRA | retinoid receptor agonist | Details | |
| C04104 | BRD-K16758059 | perfluamine | Details | |||
| C04105 | BRD-K92988025 | perflubron | contrast agent | Details | ||
| C04106 | BRD-K55401595 | perfluorodecalin | Details | |||
| C04107 | BRD-K60770992 | pergolide | ADRA1A|ADRA1B|ADRA1D|ADRA2A|ADRA2B|ADRA2C|DRD1|DRD2|DRD3|DRD4|DRD5|HTR1A|HTR1B|HTR1D|HTR2A|HTR2B|HTR2C | dopamine receptor agonist | Details | |
| C04108 | BRD-A19633847 | perhexiline | CPT1A|CPT2 | carnitine palmitoyltransferase inhibitor | Details | |
| C04109 | BRD-A89082344 | perifosine | AKT1 | AKT inhibitor | Details | |
| C04110 | BRD-A13323580 | perillyl-alcohol | FNTA | apoptosis stimulant; farnesyltransferase inhibitor | Details | |
| C04111 | BRD-K92731339 | perindopril | ACE | angiotensin converting enzyme inhibitor | Details | |
| C04112 | BRD-K00768353 | perindoprilat | ACE | angiotensin converting enzyme inhibitor | Details | |
| C04113 | BRD-A25366096 | permethrin | SCN1A | Details | ||
| C04114 | BRD-K85503079 | perospirone | DRD2|DRD3|DRD4 | dopamine receptor antagonist; serotonin receptor antagonist | Details | |
| C04115 | BRD-K10995081 | perphenazine | CALM1|DRD1|DRD2|HRH1|HTR2A|HTR2C|HTR6|HTR7 | dopamine receptor antagonist | Details | |
| C04116 | BRD-A72716251 | peruvoside | cardiac glycoside | Details | ||
| C04117 | BRD-K04643877 | perzinfotel | GRIN1|GRIN2A|GRIN2B | glutamate receptor antagonist | Details | |
| C04118 | BRD-A93477898 | PETCM | CASP3 | caspase activator | Details | |
| C04119 | BRD-K67844266 | pevonedistat | NAE1|UBA3 | nedd activating enzyme inhibitor | Details | |
| C04120 | BRD-K54519451 | pexidartinib | CSF1R|FLT3|KIT | tyrosine kinase inhibitor | Details | |
| C04121 | BRD-K53405000 | pexmetinib | MAPK14|TEK | TIE tyrosine kinase inhibitor; MAP kinase inhibitor | Details | |
| C04122 | BRD-K31519811 | PF-02545920 | PDE10A | phosphodiesterase inhibitor | Details | |
| C04123 | BRD-K07070922 | PF-03049423 | PDE5A | phosphodiesterase inhibitor | Details | |
| C04124 | BRD-K61691541 | PF-03084014 | gamma secretase inhibitor | Details | ||
| C04125 | BRD-K37764012 | PF-03758309 | PAK4 | p21 activated kinase inhibitor | Details | |
| C04126 | BRD-K68747584 | PF-03814735 | AURKA|AURKB | Aurora kinase inhibitor | Details | |
| C04127 | BRD-K51041191 | PF-03882845 | Details | |||
| C04128 | BRD-K94420399 | PF-04136309 | CC chemokine receptor antagonist | Details | ||
| C04129 | BRD-K73319509 | PF-04217903 | MET | c-Met inhibitor | Details | |
| C04130 | BRD-K54871792 | PF-04418948 | PTGER2 | prostaglandin inhibitor | Details | |
| C04131 | BRD-K50031829 | PF-04447943 | PDE9A | phosphodiesterase inhibitor | Details | |
| C04132 | BRD-K86816506 | PF-04457845 | FAAH | FAAH inhibitor | Details | |
| C04133 | BRD-K30550578 | PF-04620110 | DGAT1 | diacylglycerol O acyltransferase inhibitor | Details | |
| C04134 | BRD-K07310275 | PF-04691502 | MTOR|PIK3CA | mTOR inhibitor; PI3K inhibitor | Details | |
| C04135 | BRD-K92435527 | PF-04885614 | SCN10A | voltage-gated sodium channel blocker | Details | |
| C04136 | BRD-K27755542 | PF-04937319 | GCK | glucokinase activator | Details | |
| C04137 | BRD-K02554563 | PF-05190457 | GHSR | growth hormone secretagogue receptor inverse agonist | Details | |
| C04138 | BRD-K07955840 | PF-05212384 | MTOR|PIK3CA | mTOR inhibitor; PI3K inhibitor | Details | |
| C04139 | BRD-K83114366 | PF-06447475 | LRRK2 | serine/threonine kinase inhibitor | Details | |
| C04140 | BRD-A23124853 | PF-06463922 | ALK|FES|ROS1 | ALK tyrosine kinase receptor inhibitor | Details | |
| C04141 | BRD-K31417912 | PF-3274167 | AVPR1A|OXTR | oxytocin receptor antagonist | Details | |
| C04142 | BRD-K68997413 | PF-3845 | FAAH | FAAH inhibitor | Details | |
| C04143 | BRD-K11821338 | PF-429242 | MBTPS1 | SREBP inhibitor | Details | |
| C04144 | BRD-K93788137 | PF-431396 | PTK2|PTK2B | focal adhesion kinase inhibitor | Details | |
| C04145 | BRD-K14711741 | PF-4708671 | RPS6KB1 | ribosomal protein inhibitor | Details | |
| C04146 | BRD-K03063480 | PF-477736 | CHEK1|CHEK2 | CHK inhibitor | Details | |
| C04147 | BRD-K43428468 | PF-4800567 | CSNK1D|CSNK1E | casein kinase inhibitor | Details | |
| C04148 | BRD-K78318619 | PF-4981517 | CYP3A4 | cytochrome P450 inhibitor | Details | |
| C04149 | BRD-K40302533 | PF-5274857 | SMO | smoothened receptor antagonist | Details | |
| C04150 | BRD-K99545815 | PF-562271 | PTK2|PTK2B | focal adhesion kinase inhibitor | Details | |
| C04151 | BRD-K79239947 | PF-573228 | CDK1|CDK2|CDK7|GSK3B|IKBKB | focal adhesion kinase inhibitor | Details | |
| C04152 | BRD-K96295391 | PF-670462 | CSNK1D|CSNK1E | casein kinase inhibitor | Details | |
| C04153 | BRD-K83213911 | PF-750 | FAAH | FAAH inhibitor | Details | |
| C04154 | BRD-K50865540 | PF-8380 | ENPP2 | autotaxin inhibitor | Details | |
| C04155 | BRD-K18289362 | PF-915275 | HSD11B1 | 11-beta hydroxysteroid dehydrogenase inhibitor | Details | |
| C04156 | BRD-K13094524 | PFI-1 | BRD4 | bromodomain inhibitor | Details | |
| C04157 | BRD-K61524559 | PFI-3 | PBRM1|SMARCA4 | bromodomain inhibitor | Details | |
| C04158 | BRD-K13106865 | PFI-4 | BRPF1 | bromodomain inhibitor | Details | |
| C04159 | BRD-K95573441 | PFK-015 | PFKFB3 | phosphofructokinase inhibitor | Details | |
| C04160 | BRD-K28010364 | PFK-158 | PFKFB3 | phosphofructokinase inhibitor | Details | |
| C04161 | BRD-A70268693 | PG-9 | acetylcholine receptor agonist | Details | ||
| C04162 | BRD-A53813595 | PGL5001 | MAPK10|MAPK8|MAPK9 | JNK inhibitor | Details | |
| C04163 | BRD-K95880107 | PH-797804 | MAPK11|MAPK14 | p38 MAPK inhibitor | Details | |
| C04164 | BRD-K48053228 | PHA-568487 | CHRNA7 | nicotinic receptor agonist | Details | |
| C04165 | BRD-K95435023 | PHA-665752 | MET | c-Met inhibitor | Details | |
| C04166 | BRD-K09443272 | PHA-680632 | AURKA|AURKB|AURKC | Aurora kinase inhibitor | Details | |
| C04167 | BRD-K50000283 | PHA-767491 | CDK1|RPS6KB1 | CDC inhibitor | Details | |
| C04168 | BRD-K64800655 | PHA-793887 | CDK1|CDK2|CDK4|CDK5|CDK7|CDK9 | CDK inhibitor | Details | |
| C04169 | BRD-K60997853 | PHA-848125 | CDK2|CDK4|CDK7|NTRK1 | CDK inhibitor; growth factor receptor inhibitor | Details | |
| C04170 | BRD-A59709458 | PHCCC | GRM1|GRM4 | glutamate receptor agonist | Details | |
| C04171 | BRD-K81092066 | phenacaine | local anesthetic | Details | ||
| C04172 | BRD-K40905133 | phenacemide | SCN10A|SCN11A|SCN1A|SCN2A|SCN3A|SCN4A|SCN5A|SCN7A|SCN8A|SCN9A | sodium channel blocker | Details | |
| C04173 | BRD-K38323065 | phenacetin | PTGS1 | cyclooxygenase inhibitor | Details | |
| C04174 | BRD-K46937689 | phenazone | PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C04175 | BRD-K76304753 | phenazopyridine | SCN1A | local anesthetic | Details | |
| C04176 | BRD-K87024524 | phenelzine | ABAT|AOC3|GAD2|GPT|GPT2|MAOA|MAOB|SLC6A2|SLC6A3|SLC6A4 | monoamine oxidase inhibitor | Details | |
| C04177 | BRD-A66025870 | phenethicillin | bacterial cell wall synthesis inhibitor | Details | ||
| C04178 | BRD-K56700933 | phenethyl-isothiocyanate | CYP2E1 | anticancer agent | Details | |
| C04179 | BRD-K11399644 | phenformin | KCNJ8|PRKAA1 | AMPK activator | Details | |
| C04180 | BRD-A33178345 | phenindamine | HRH1 | histamine receptor antagonist | Details | |
| C04181 | BRD-K70592963 | phenindione | VKORC1 | vitamin K antagonist | Details | |
| C04182 | BRD-A23072235 | pheniramine | HRH1 | histamine receptor antagonist | Details | |
| C04183 | BRD-K76549667 | phenol | CA1|CA12|CA14|CA2|CA4|CA9 | Details | ||
| C04184 | BRD-K19227686 | phenolphthalein | UGT1A9 | indicator dye | Details | |
| C04185 | BRD-K79892937 | phenolsulfonphthalein | Details | |||
| C04186 | BRD-K59597909 | phenothiazine | dopamine receptor antagonist | Details | ||
| C04187 | BRD-A22106989 | phenothrin | Details | |||
| C04188 | BRD-A67799922 | phenoxybenzamine | ADRA1A|ADRA1B|ADRA1D|ADRA2A|ADRA2B|ADRA2C|ADRB2|CALM1 | adrenergic receptor antagonist | Details | |
| C04189 | BRD-K22009844 | phenprobamate | muscle relaxant | Details | ||
| C04190 | BRD-A49838158 | phenprocoumon | VKORC1 | vitamin K antagonist | Details | |
| C04191 | BRD-K46580984 | phenserine | ACHE|BCHE | acetylcholinesterase inhibitor; beta amyloid synthesis inhibitor | Details | |
| C04192 | BRD-A18043272 | phensuximide | CACNA1G|CACNA1H|CACNA1I | succinimide antiepileptic | Details | |
| C04193 | BRD-K96319534 | phentermine | MAOA|MAOB|SLC6A2|SLC6A3|SLC6A4 | dopamine uptake inhibitor; serotonin reuptake inhibitor | Details | |
| C04194 | BRD-K90333595 | phentolamine | ADRA1A|ADRA1B|ADRA1D|ADRA2A|ADRA2B|ADRA2C | adrenergic receptor antagonist | Details | |
| C04195 | BRD-K73157543 | phenyl-aminosalicylate | Details | |||
| C04196 | BRD-K44091963 | phenyl-salicylate | antiseptic | Details | ||
| C04197 | BRD-K70592483 | phenylacetylglutamine | DNA methylase inhibitor; protein synthesis inhibitor | Details | ||
| C04198 | BRD-K02729857 | phenylbenzimidazole-sulfonic-acid | Details | |||
| C04199 | BRD-K10843433 | phenylbutazone | PTGIS|PTGS1|PTGS2 | cyclooxygenase inhibitor; prostanoid receptor antagonist | Details | |
| C04200 | BRD-K67102207 | phenylbutyrate | HDAC1 | HDAC inhibitor | Details |