CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C02201 | BRD-K21913543 | fluorescein | SLC22A6 | Details | ||
| C02202 | BRD-A13133631 | fluorometholone | NR3C1 | glucocorticoid receptor agonist | Details | |
| C02203 | BRD-K02528732 | fluorometholone-acetate | NR3C1 | Details | ||
| C02204 | BRD-K51199656 | fluoromethylcholine | Details | |||
| C02205 | BRD-A31159102 | fluoxetine | ANO1|HTR2B|SLC6A4 | selective serotonin reuptake inhibitor (SSRI) | Details | |
| C02206 | BRD-K24255045 | fluoxymesterone | AR|ESR1|NR3C1|PRLR | androgen receptor modulator | Details | |
| C02207 | BRD-K70487031 | flupentixol | ADRA1A|CHRM1|DRD1|DRD2|DRD3|DRD5|HTR2A | dopamine receptor antagonist | Details | |
| C02208 | BRD-K55127134 | fluphenazine | CALM1|DRD1|DRD2|DRD5|HRH1|HTR2A|HTR6|HTR7 | dopamine receptor antagonist | Details | |
| C02209 | BRD-K27898013 | fluphenazine-decanoate | DRD2|HTR1B|HTR4 | dopamine receptor antagonist | Details | |
| C02210 | BRD-K50720187 | flupirtine | ADRA2A|KCNQ1|KCNQ2 | glutamate receptor antagonist | Details | |
| C02211 | BRD-K44091134 | fluprazine | HTR1A|HTR1B | serotonin receptor agonist | Details | |
| C02212 | BRD-A86044036 | flurbiprofen-(+/-) | PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C02213 | BRD-K69907333 | flurbiprofen-(S)-(+) | PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C02214 | BRD-K75410565 | flurizan | APH1B|BACE1|IKBKG|PSEN1|PSEN2|PTGS1|PTGS2 | gamma secretase inhibitor | Details | |
| C02215 | BRD-K67445247 | flurofamide | urease inhibitor | Details | ||
| C02216 | BRD-K14763542 | flurothyl | Details | |||
| C02217 | BRD-K56908511 | fluroxene | local anesthetic | Details | ||
| C02218 | BRD-K77947974 | fluspirilene | CACNG1|DRD2|HRH1|HTR1A|HTR1D|HTR1E|HTR2A | dopamine receptor antagonist | Details | |
| C02219 | BRD-K28307902 | flutamide | AHR|AR | androgen receptor antagonist | Details | |
| C02220 | BRD-K62310379 | fluticasone-propionate | NR3C1|NR3C2|PGR|PLA2G4A | glucocorticoid receptor agonist | Details | |
| C02221 | BRD-A00218260 | flutrimazole | sterol demethylase inhibitor | Details | ||
| C02222 | BRD-K66296774 | fluvastatin | HMGCR | HMGCR inhibitor | Details | |
| C02223 | BRD-K53517854 | fluvoxamine | SLC6A4 | selective serotonin reuptake inhibitor (SSRI) | Details | |
| C02224 | BRD-K15327298 | fmoc-l-leucine | PPAR receptor agonist | Details | ||
| C02225 | BRD-K18673820 | folic-acid | FOLR2|FOLR3|SLC19A1|SLC46A1 | folate receptor ligand | Details | |
| C02226 | BRD-K56810756 | fomepizole | ADH1A|ADH1B|ADH1C|AKR1A1|CAT | alcohol dehydrogenase inhibitor | Details | |
| C02227 | BRD-K44942188 | fomocaine | voltage-gated sodium channel modulator | Details | ||
| C02228 | BRD-K03449891 | foretinib | FLT1|FLT4|KDR|MET | VEGFR inhibitor | Details | |
| C02229 | BRD-A26503646 | formestane | CYP19A1 | aromatase inhibitor | Details | |
| C02230 | BRD-K55567017 | formononetin | ADH1C|SLC5A2 | alcohol dehydrogenase inhibitor | Details | |
| C02231 | BRD-K54006094 | formoterol | ADRB2 | adrenergic receptor agonist | Details | |
| C02232 | BRD-K16505263 | forodesine | PNP | purinergic receptor antagonist | Details | |
| C02233 | BRD-K57774929 | foropafant | PTAFR | platelet activating factor receptor antagonist | Details | |
| C02234 | BRD-K09602097 | forskolin | ADCY2|ADCY5|GNAS | adenylyl cyclase activator | Details | |
| C02235 | BRD-K59110290 | fosamprenavir | HIV protease inhibitor | Details | ||
| C02236 | BRD-K23848629 | fosaprepitant-dimeglumine | TACR1 | tachykinin antagonist | Details | |
| C02237 | BRD-K68399195 | fosbretabulin | CDH5 | tubulin polymerization inhibitor; VE-cadherin antagonist | Details | |
| C02238 | BRD-K85146014 | foscarnet | DNA polymerase inhibitor | Details | ||
| C02239 | BRD-K20801936 | fosfestrol | ESR1|ESR2 | synthetic estrogen | Details | |
| C02240 | BRD-K81101512 | fosfomycin | bacterial cell wall synthesis inhibitor | Details | ||
| C02241 | BRD-K28687144 | fosfosal | PTGS1|PTGS2 | phosphodiesterase inhibitor | Details | |
| C02242 | BRD-A19086570 | fosfructose | PKLR | fructose diphosphate stimulant | Details | |
| C02243 | BRD-A51382177 | fosinopril | ACE | angiotensin converting enzyme inhibitor | Details | |
| C02244 | BRD-A33506612 | fosinoprilat | ACE | angiotensin converting enzyme inhibitor | Details | |
| C02245 | BRD-K53809807 | fosphenytoin | SCN5A | sodium channel blocker | Details | |
| C02246 | BRD-K85178109 | fostamatinib | SYK | SYK inhibitor | Details | |
| C02247 | BRD-A62893078 | fotemustine | TXNRD1 | thioredoxin inhibitor | Details | |
| C02248 | BRD-K13005598 | foxy-5 | WNT5A | WNT5a peptide mimetic | Details | |
| C02249 | BRD-M17926088 | FPA-124 | AKT inhibitor | Details | ||
| C02250 | BRD-K61250484 | FPH1-(BRD-6125) | hepatocyte function enhancer | Details | ||
| C02251 | BRD-A09368919 | FPL-12495 | glutamate receptor antagonist | Details | ||
| C02252 | BRD-A96456596 | FPL-55712 | leukotriene receptor antagonist | Details | ||
| C02253 | BRD-K59875992 | FPL-62064 | cyclooxygenase inhibitor; lipoxygenase inhibitor | Details | ||
| C02254 | BRD-K78959463 | FPL-64176 | CACNA1C|CACNA1S | calcium channel activator | Details | |
| C02255 | BRD-K87691185 | FPS-ZM1 | AGER | RAGE receptor antagonist | Details | |
| C02256 | BRD-K30990140 | FR-122047 | cyclooxygenase inhibitor | Details | ||
| C02257 | BRD-K19318328 | FR-139317 | EDNRA | endothelin receptor antagonist | Details | |
| C02258 | BRD-K68756823 | FR-180204 | MAPK1|MAPK3 | MAP kinase inhibitor | Details | |
| C02259 | BRD-K57243773 | FRAX486 | PAK1|PAK2|PAK3|PAK4 | serine/threonine kinase inhibitor | Details | |
| C02260 | BRD-K07202345 | frentizole | immunosuppressant | Details | ||
| C02261 | BRD-K08255599 | frovatriptan | HTR1A|HTR1B|HTR1D | serotonin receptor agonist | Details | |
| C02262 | BRD-K70504253 | fruquintinib | KDR | VEGFR inhibitor | Details | |
| C02263 | BRD-K05724540 | ftaxilide | Details | |||
| C02264 | BRD-K99383816 | ftorafur | TYMS | thymidylate synthase inhibitor | Details | |
| C02265 | BRD-K54838207 | fudosteine | mucolytic agent | Details | ||
| C02266 | BRD-A85667082 | fulvestrant | ESR1|ESR2|GPER1 | estrogen receptor antagonist | Details | |
| C02267 | BRD-A99367815 | fumagillin | METAP2 | methionine aminopeptidase inhibitor | Details | |
| C02268 | BRD-A67514145 | furaltadone | bacterial DNA inhibitor | Details | ||
| C02269 | BRD-K77758223 | furamidine | PRMT1 | protein arginine N-methyltransferase inhibitor | Details | |
| C02270 | BRD-K11756522 | furazolidone | bacterial DNA inhibitor | Details | ||
| C02271 | BRD-K55529781 | furegrelate | TBXAS1 | thromboxane synthase inhibitor | Details | |
| C02272 | BRD-K78010432 | furosemide | CA2|GPR35|SLC12A1|SLC12A2 | diuretic | Details | |
| C02273 | BRD-A71157293 | fursultiamine | vitamin B | Details | ||
| C02274 | BRD-A06935312 | fusidic-acid | bacterial 30S ribosomal subunit inhibitor | Details | ||
| C02275 | BRD-K41267922 | F351 | TGFB1 | TGF beta receptor inhibitor | Details | |
| C02276 | BRD-K26878113 | g-caryophyllene | ACHE | acetylcholinesterase inhibitor | Details | |
| C02277 | BRD-K62696033 | G-1 | GPER1 | G protein-coupled receptor agonist | Details | |
| C02278 | BRD-M30288325 | G-15 | GPER1 | estrogen receptor antagonist | Details | |
| C02279 | BRD-K46254452 | GABA-linoleamide | benzodiazepine receptor agonist | Details | ||
| C02280 | BRD-K62737565 | gabapentin | ADORA1|CACNA1A|CACNA1B|CACNA1C|CACNA1D|CACNA1E|CACNA1F|CACNA1G|CACNA1H|CACNA1I|CACNA1S|CACNA2D1|CACNA2D2|CACNA2D3|CACNA2D4|CACNB1|CACNB2|CACNB3|CACNB4|CACNG1|CACNG2|CACNG3|CACNG4|CACNG5|CACNG6|CACNG7|CACNG8|GRIN1|GRIN2A|GRIN2B|GRIN2C|GRIN2D|GRIN3A|GRIN3B | calcium channel blocker | Details | |
| C02281 | BRD-A86665761 | gabapentin-enacarbil | CACNA1A|CACNA1B|CACNA1C|CACNA1D|CACNA1E|CACNA1F|CACNA1G|CACNA1H|CACNA1I|CACNA1S|CACNA2D1|CACNA2D2|CACNA2D3|CACNA2D4|CACNB1|CACNB2|CACNB3|CACNB4|CACNG1|CACNG2|CACNG3|CACNG4|CACNG5|CACNG6|CACNG7|CACNG8 | adrenergic receptor agonist | Details | |
| C02282 | BRD-K79905821 | gabazine | GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRG2 | GABA receptor antagonist | Details | |
| C02283 | BRD-K59256312 | gabexate | PRSS1|TPSAB1 | serine protease inhibitor | Details | |
| C02284 | BRD-K89104321 | gaboxadol | GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRD|GABRR1|GABRR2|GABRR3 | benzodiazepine receptor agonist | Details | |
| C02285 | BRD-A67181951 | gadobutrol | radiopaque medium | Details | ||
| C02286 | BRD-K38140108 | gadodiamide | radiopaque medium | Details | ||
| C02287 | BRD-K25106841 | gadopentetic-acid | contrast agent | Details | ||
| C02288 | BRD-K11099631 | gadoterate-meglumine | radiopaque medium | Details | ||
| C02289 | BRD-A72401848 | gadoteridol | radiopaque medium | Details | ||
| C02290 | BRD-K49481516 | galantamine | ACHE|BCHE|CHRNA1|CHRNA10|CHRNA2|CHRNA3|CHRNA4|CHRNA5|CHRNA6|CHRNA7|CHRNA9|CHRNB1|CHRNB2|CHRNB3|CHRNB4|CHRND|CHRNE|CHRNG | acetylcholinesterase inhibitor | Details | |
| C02291 | BRD-A07986123 | galeterone | AR|CYP17A1 | androgen receptor modulator | Details | |
| C02292 | BRD-K43106192 | gallamine-triethiodide | ACHE|CHRM2|CHRNA1|CHRNA2 | acetylcholine receptor antagonist | Details | |
| C02293 | BRD-K77345217 | gallic-acid | CA1|CA12|CA14|CA2|CA4|CA6|CA9|SELP | beta amyloid protein neurotoxicity inhibitor; PPAR receptor agonist | Details | |
| C02294 | BRD-K46648676 | gallium-triquinolin-8-olate | Details | |||
| C02295 | BRD-A52922642 | gallopamil | ATP2A2 | L-type calcium channel blocker | Details | |
| C02296 | BRD-K08542803 | gambogic-acid | BCL2 | caspase activator | Details | |
| C02297 | BRD-K77245796 | gamma-aminobutyric-acid | GABBR1|GABBR2|GABRA1|GABRA2|GABRA3|GABRA5|GABRB2|GABRG2|GATM|KCTD12|KCTD16|KCTD8|SLC6A1 | benzodiazepine receptor agonist | Details | |
| C02298 | BRD-K18059238 | gamma-linolenic-acid | PTGS1|PTGS2 | cyclooxygenase inhibitor; prostanoid receptor agonist | Details | |
| C02299 | BRD-K28217197 | ganaxolone | GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6 | GABA receptor modulator | Details | |
| C02300 | BRD-K22662435 | ganciclovir | DNA polymerase inhibitor | Details |