CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C04401 | BRD-K19352500 | prochlorperazine | DRD1|DRD2|DRD3|DRD4 | dopamine receptor antagonist | Details | |
| C04402 | BRD-K54824716 | procodazole | immunostimulant | Details | ||
| C04403 | BRD-K72093555 | procyanidin-b-2 | Details | |||
| C04404 | BRD-A31800922 | procyclidine | CHRM1|CHRM2|CHRM3|CHRM4 | acetylcholine receptor antagonist | Details | |
| C04405 | BRD-K92413528 | procysteine | glutathione synthase stimulant | Details | ||
| C04406 | BRD-A16311756 | profenamine | CHRM1|CHRM2|GRIN3A | butyrylcholinesterase inhibitor; cholinergic receptor antagonist | Details | |
| C04407 | BRD-K68408467 | proflavine-hemisulfate | F2 | topical anesthetic | Details | |
| C04408 | BRD-K64994968 | progesterone | CATSPER1|CATSPER2|CATSPER3|CATSPER4|CYP17A1|ESR1|NR3C2|OPRK1|PGR|TRPC5 | progesterone receptor agonist | Details | |
| C04409 | BRD-A19458515 | proglumetacin | PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C04410 | BRD-A44863528 | proglumide | CCKAR|CCKBR | CCK receptor antagonist | Details | |
| C04411 | BRD-K28183345 | proguanil | DHFR | dihydrofolate reductase inhibitor | Details | |
| C04412 | BRD-A09911125 | prolylleucylglycinamide | melanocyte-stimulating hormone release inhibitor | Details | ||
| C04413 | BRD-K06980535 | promazine | ADRA1A|ADRA1B|ADRA1D|CHRM1|CHRM2|CHRM3|CHRM4|CHRM5|DRD1|DRD2|DRD3|DRD4|HRH1|HTR2A|HTR2C | dopamine receptor antagonist | Details | |
| C04414 | BRD-K75097983 | promestriene | ESR1 | estrogen receptor agonist | Details | |
| C04415 | BRD-A46335897 | promethazine | ADRA1A|CALM1|CHRM1|CHRM2|CHRM3|CHRM4|CHRM5|DRD2|HRH1|HTR2A | histamine receptor antagonist | Details | |
| C04416 | BRD-A87715314 | pronethalol | adrenergic receptor antagonist | Details | ||
| C04417 | BRD-K54496168 | propacetamol | PTGS2 | cyclooxygenase inhibitor | Details | |
| C04418 | BRD-A26334849 | propafenone | ADRB1|ADRB2|KCNA5|KCNH2|SCN5A | antiarrhythmic | Details | |
| C04419 | BRD-K53382462 | propagermanium | CCR2 | interferon receptor agonist; CCR agonist | Details | |
| C04420 | BRD-K90885812 | propantheline | CHRM1|CHRM2|CHRM3|CHRM4 | acetylcholine receptor antagonist | Details | |
| C04421 | BRD-K56276053 | propatylnitrate | Details | |||
| C04422 | BRD-K59273480 | propentofylline | PDE1A | adenosine reuptake inhibitor; phosphodiesterase inhibitor | Details | |
| C04423 | BRD-K14821965 | propidium-iodide | ACHE | Details | ||
| C04424 | BRD-K76867903 | propiolactone | Details | |||
| C04425 | BRD-K91244729 | propiverine | CHRM1 | acetylcholine receptor antagonist | Details | |
| C04426 | BRD-K82255054 | propofol | FAAH|GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRB1|GABRB2|GABRB3|GABRD|GABRE|GABRG1|GABRG2|GABRG3|GABRP|GABRQ|SCN2A|SCN4A | benzodiazepine receptor agonist | Details | |
| C04427 | BRD-K08231299 | propoxur | Details | |||
| C04428 | BRD-K18250272 | propoxycaine | local anesthetic | Details | ||
| C04429 | BRD-A10070317 | propranolol | adrenergic receptor antagonist | Details | ||
| C04430 | BRD-K92830582 | propranolol-(R) | ADRB2|ADRB3 | adrenergic receptor antagonist | Details | |
| C04431 | BRD-K13994703 | propranolol-(S) | ADRB1|ADRB2|ADRB3|HTR1A|HTR1B|HTR5A|SLC10A1 | adrenergic receptor antagonist | Details | |
| C04432 | BRD-K15329706 | propyl-benzoate | Details | |||
| C04433 | BRD-A19232309 | propylene-glycol | F13A1 | Details | ||
| C04434 | BRD-A35667010 | propylhexedrine | SLC18A2|TAAR1 | adrenergic receptor agonist | Details | |
| C04435 | BRD-K60783397 | propylparaben | Details | |||
| C04436 | BRD-K48168960 | propylthiouracil | DIO1|TPO | thyroid peroxidase inhibitor | Details | |
| C04437 | BRD-K54339150 | proquazone | PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C04438 | BRD-A11815689 | proscillaridin-a | Details | |||
| C04439 | BRD-K75360161 | protionamide | Details | |||
| C04440 | BRD-A16997652 | protirelin | TRHR | thyrotropin releasing hormone receptor agonist | Details | |
| C04441 | BRD-K26813314 | protoporphyrin-ix | HMOX1 | heme oxygenase inhibitor | Details | |
| C04442 | BRD-K42098891 | protriptyline | SLC6A2|SLC6A4 | tricyclic antidepressant | Details | |
| C04443 | BRD-A29944538 | proxodolol | adrenergic receptor antagonist | Details | ||
| C04444 | BRD-K77171813 | proxyfan | HRH3 | histamine receptor modulator | Details | |
| C04445 | BRD-K79116891 | proxymetacaine | SCN10A|SCN5A | sodium channel blocker | Details | |
| C04446 | BRD-A28887267 | proxyphylline | Details | |||
| C04447 | BRD-K25835157 | PRT062070 | SYK | JAK inhibitor; syk inhibitor | Details | |
| C04448 | BRD-K53734668 | PRT062607 | FGR|MAP3K9|SYK | syk inhibitor | Details | |
| C04449 | BRD-K32456483 | PRT4165 | PRC1 | polycomb repressive complex inhibitor | Details | |
| C04450 | BRD-K33681278 | prucalopride | HTR4 | serotonin receptor agonist | Details | |
| C04451 | BRD-A92341659 | prulifloxacin | bacterial DNA gyrase inhibitor | Details | ||
| C04452 | BRD-K43837174 | pruvanserin | HTR2A|HTR2C | serotonin receptor antagonist | Details | |
| C04453 | BRD-K16757695 | PRX-08066 | HTR2B | serotonin receptor antagonist | Details | |
| C04454 | BRD-K71266197 | PSB-06126 | ENTPD3 | NTPDase inhibitor | Details | |
| C04455 | BRD-K10177585 | PSB-11 | ADORA1|ADORA2A|ADORA3 | adenosine receptor antagonist | Details | |
| C04456 | BRD-K49027941 | PSB-1115 | ADORA1|ADORA2B|ADORA3 | adenosine receptor antagonist | Details | |
| C04457 | BRD-A70407468 | PSB-36 | ADORA1|ADORA2A|ADORA2B|ADORA3 | adenosine receptor antagonist | Details | |
| C04458 | BRD-K05419687 | PSB-603 | ADORA1|ADORA2A|ADORA2B|ADORA3 | adenosine receptor antagonist | Details | |
| C04459 | BRD-K07798980 | PSI-6130 | RNA polymerase inhibitor | Details | ||
| C04460 | BRD-K05674516 | PSI-7976 | HCV inhibitor | Details | ||
| C04461 | BRD-K25524093 | PSN-375963 | GPR119 | glucose dependent insulinotropic receptor agonist | Details | |
| C04462 | BRD-K33502629 | PSNCBAM-1 | CNR1 | cannabinoid receptor modulator | Details | |
| C04463 | BRD-K47264279 | psoralen | MAOA|MAOB | Details | ||
| C04464 | BRD-K99092662 | PS178990 | AR | androgen receptor modulator | Details | |
| C04465 | BRD-K20850787 | PT-2385 | EPAS1 | hypoxia inducible factor inhibitor | Details | |
| C04466 | BRD-K83834509 | PTC-209 | BMI-1 inhibitor | Details | ||
| C04467 | BRD-K53097745 | pterostilbene | PTGS2 | cyclooxygenase inhibitor; PPAR receptor agonist | Details | |
| C04468 | BRD-K36529613 | PU-H71 | HSP90AA1 | HSP inhibitor | Details | |
| C04469 | BRD-K89048337 | puerarin | serotonin receptor antagonist | Details | ||
| C04470 | BRD-K44164034 | pumosetrag | HTR3A|HTR4 | serotonin receptor agonist | Details | |
| C04471 | BRD-K73397362 | purmorphamine | SMO | smoothened receptor agonist | Details | |
| C04472 | BRD-A28970875 | puromycin | NHP2L1|RPL10L|RPL11|RPL13A|RPL15|RPL19|RPL23|RPL23A|RPL26L1|RPL3|RPL37|RPL8|RSL24D1 | protein synthesis inhibitor | Details | |
| C04473 | BRD-K50836978 | purvalanol-a | CDK1|CDK2|CDK4|CDK5|CSNK1G3|RPS6KA1|SRC | CDK inhibitor | Details | |
| C04474 | BRD-K41564320 | purvalanol-b | CDK2|CDK4|CDK5|MAPK1|MAPK3|SRPK2 | tyrosine kinase inhibitor | Details | |
| C04475 | BRD-K75282878 | putrescine | AMD1|KCNJ4|ODC1 | tissue transglutaminase inhibitor | Details | |
| C04476 | BRD-A56592690 | PX-12 | TXN|TXNRD1 | thioredoxin inhibitor | Details | |
| C04477 | BRD-A26835809 | PX-478 | hypoxia inducible factor inhibitor | Details | ||
| C04478 | BRD-K62277907 | PYM50028 | neurotrophic agent | Details | ||
| C04479 | BRD-K66101666 | PYR-41 | ubiquitin activating enzyme inhibitor | Details | ||
| C04480 | BRD-K82118441 | pyrantel | nicotinic receptor agonist | Details | ||
| C04481 | BRD-K20672254 | pyrantel-pamoate | neuromuscular blocker | Details | ||
| C04482 | BRD-K20672254 | pyrantel-tartrate | CHRNA1 | acetylcholine receptor agonist | Details | |
| C04483 | BRD-K28667793 | pyrazinamide | FASN | fatty acid synthase inhibitor | Details | |
| C04484 | BRD-K61693562 | pyrazinoylguanidine | diuretic | Details | ||
| C04485 | BRD-K01567962 | pyrazolanthrone | MAPK10|MAPK8|MAPK8IP1|MAPK9|TTK | JNK inhibitor | Details | |
| C04486 | BRD-K42607789 | pyrazoloacridine | TOP1|TOP2A | topoisomerase inhibitor | Details | |
| C04487 | BRD-K79856453 | pyrethrins | Details | |||
| C04488 | BRD-K76204040 | pyridoxal | PDXK | Details | ||
| C04489 | BRD-K42019693 | pyridoxal-isonicotinoyl-hydrazone | apoptosis stimulant | Details | ||
| C04490 | BRD-K96669468 | pyridoxamine | AGE inhibitor | Details | ||
| C04491 | BRD-K14349461 | pyridoxine | DDC|PDXK | vitamin B | Details | |
| C04492 | BRD-K88429204 | pyrimethamine | DHFR|SLC47A1 | dihydrofolate reductase inhibitor | Details | |
| C04493 | BRD-K94659840 | pyrintegrin | integrin signaling activator | Details | ||
| C04494 | BRD-K16136380 | pyrithione-zinc | KCNQ1|KCNQ2|KCNQ4|KCNQ5 | ATP synthase inhibitor | Details | |
| C04495 | BRD-K36116267 | pyrithyldione | psychoactive drug | Details | ||
| C04496 | BRD-K82181219 | pyritinol | Details | |||
| C04497 | BRD-K73132780 | pyronaridine | antimalarial agent | Details | ||
| C04498 | BRD-K11663430 | pyroxamide | HDAC1 | HDAC inhibitor | Details | |
| C04499 | BRD-K80970344 | pyrrolidine-dithiocarbamate | HSD11B1|RELA | NFkB pathway inhibitor | Details | |
| C04500 | BRD-M55114534 | pyrvinium | androgen receptor antagonist | Details |