Research Article Details
| Article ID: | A00081 |
| PMID: | 16609882 |
| Source: | Hum Genet |
| Title: | A large-scale genetic association study of ossification of the posterior longitudinal ligament of the spine. |
| Abstract: | Research to date has identified several genes that are implicated in the etiology of ossification of the posterior longitudinal ligament of the spine (OPLL); however, their pathogenetic relevance remains obscure. The aim of this study is to identify susceptibility genes for OPLL through a large-scale case-control association study and to re-examine previously reported associations. A total of 109 single nucleotide polymorphisms (SNPs) in 35 candidate genes were genotyped for 711 sporadic OPLL patients and 896 controls. The differences in allelic and genotypic distribution between patients and controls were assessed using the chi (2) test with Bonferroni's correction. We also analyzed the association by separating patients into subgroups according to sex, age and the number of ossified vertebrae. The nominal P values fell below 0.05 for five SNPs in three genes. An intronic SNP in the TGF3 gene (P=0.00040) showed the most significant association. Previously reported associations of COL11A2, NPPS and TGFB1 with OPLL could not be reproduced. Further, no significant associations were detected in stratified analyses based on sex, age or the number of ossified vertebrae. TGFB3 warrants further investigation because it is located within a genomic region that has been positively linked with OPLL. |
| DOI: | 10.1007/s00439-006-0170-9 |
| Strategy ID | Therapy Strategy | Synonyms | Therapy Targets | Therapy Drugs |
|---|
| Diseases ID | DO ID | Disease Name | Definition | Class | |
|---|---|---|---|---|---|
| I02 | 1184 | nephrotic syndrome | "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability." [url:https\://en.wikipedia.org/wiki/Nephrotic_syndrome, url:https\://www.niddk.nih.gov/health-information/kidney-disease/nephrotic-syndrome-adults] | Details |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress | |
|---|---|---|---|---|---|---|---|
| D001 | Leuprolide | small molecule | DB00007 | Details | |||
| D002 | Goserelin | small molecule | DB00014 | Details | |||
| D003 | Cetrorelix | small molecule | DB00050 | Details | |||
| D004 | Pyridoxal phosphate | small molecule | DB00114 | Details | |||
| D005 | Histidine | small molecule | DB00117 | Details | |||
| D006 | Phenylalanine | small molecule | DB00120 | Details | |||
| D007 | Biotin | small molecule | DB00121 | Details | |||
| D008 | Choline | small molecule | DB00122 | Details | |||
| D009 | L-Lysine | small molecule | DB00123 | Details | |||
| D010 | Arginine | small molecule | DB00125 | Details | |||
| D011 | Ascorbic acid | small molecule | DB00126 | Details | |||
| D012 | Aspartic acid | small molecule | DB00128 | Details | |||
| D013 | Ornithine | small molecule | DB00129 | Details | |||
| D014 | L-Glutamine | small molecule | DB00130 | Details | |||
| D015 | Serine | small molecule | DB00133 | Details | |||
| D016 | Methionine | small molecule | DB00134 | Details | |||
| D017 | Tyrosine | small molecule | DB00135 | Details | |||
| D018 | Calcitriol | small molecule | DB00136 | Details | |||
| D019 | Lutein | small molecule | DB00137 | Details | |||
| D020 | Riboflavin | small molecule | DB00140 | Details | |||
| D021 | Glutamic acid | small molecule | DB00142 | Details | |||
| D022 | Phosphatidyl serine | small molecule | DB00144 | Details | |||
| D023 | Glycine | small molecule | DB00145 | Details | |||
| D024 | Calcifediol | small molecule | DB00146 | Details | |||
| D025 | Pyridoxal | small molecule | DB00147 | Details | |||
| D026 | Creatine | small molecule | DB00148 | Details | |||
| D027 | Leucine | small molecule | DB00149 | Details | |||
| D028 | Tryptophan | small molecule | DB00150 | Details | |||
| D029 | Cysteine | small molecule | DB00151 | Details | |||
| D030 | Thiamine | small molecule | DB00152 | Details | |||
| D031 | Ergocalciferol | small molecule | DB00153 | Details | |||
| D032 | Threonine | small molecule | DB00156 | Details | |||
| D033 | Alanine | small molecule | DB00160 | Details | |||
| D034 | Valine | small molecule | DB00161 | Details | |||
| D035 | Vitamin A | small molecule | DB00162 | Details | |||
| D036 | Vitamin E | small molecule | DB00163 | Details | |||
| D037 | Pyridoxine | small molecule | DB00165 | Details | |||
| D038 | Isoleucine | small molecule | DB00167 | Details | |||
| D039 | Cholecalciferol | small molecule | DB00169 | Details | |||
| D040 | Menadione | small molecule | DB00170 | Details | |||
| D041 | Proline | small molecule | DB00172 | Details | |||
| D042 | Pravastatin | small molecule | DB00175 | Details | |||
| D043 | Valsartan | small molecule | DB00177 | Details | |||
| D044 | Ramipril | small molecule | DB00178 | Details | |||
| D045 | Esmolol | small molecule | DB00187 | Details | |||
| D046 | Bortezomib | small molecule | DB00188 | Details | |||
| D047 | Phentermine | small molecule | DB00191 | Details | |||
| D048 | Tramadol | small molecule | DB00193 | Details | |||
| D049 | Fluconazole | small molecule | DB00196 | Details | |||
| D050 | Troglitazone | small molecule | DB00197 | Details | |||
| D051 | Oseltamivir | small molecule | DB00198 | Details | |||
| D052 | Erythromycin | small molecule | DB00199 | Details | |||
| D053 | Caffeine | small molecule | DB00201 | Details | |||
| D054 | Reserpine | small molecule | DB00206 | Details | |||
| D055 | Azithromycin | small molecule | DB00207 | Details | |||
| D056 | Pantoprazole | small molecule | DB00213 | Details | |||
| D057 | Torasemide | small molecule | DB00214 | Details | |||
| D058 | Citalopram | small molecule | DB00215 | Details | |||
| D059 | Moxifloxacin | small molecule | DB00218 | Details | |||
| D060 | Indinavir | small molecule | DB00224 | Details | |||
| D061 | Lovastatin | small molecule | DB00227 | Details | |||
| D062 | Pregabalin | small molecule | DB00230 | Details | |||
| D063 | Nevirapine | small molecule | DB00238 | Details | |||
| D064 | Ranolazine | small molecule | DB00243 | Details | |||
| D065 | Ziprasidone | small molecule | DB00246 | Details | |||
| D066 | Doxycycline | small molecule | DB00254 | Details | |||
| D067 | Clotrimazole | small molecule | DB00257 | Details | |||
| D068 | Metoprolol | small molecule | DB00264 | Details | |||
| D069 | Ropinirole | small molecule | DB00268 | Details | |||
| D070 | Chlorotrianisene | small molecule | DB00269 | Details | |||
| D071 | Topiramate | small molecule | DB00273 | Details | |||
| D072 | Olmesartan | small molecule | DB00275 | Details | |||
| D073 | Theophylline | small molecule | DB00277 | Details | |||
| D074 | Lidocaine | small molecule | DB00281 | Details | |||
| D075 | Pamidronic acid | small molecule | DB00282 | Details | |||
| D076 | Chlorambucil | small molecule | DB00291 | Details | |||
| D077 | Morphine | small molecule | DB00295 | Details | |||
| D078 | Bupivacaine | small molecule | DB00297 | Details | |||
| D079 | Tranexamic acid | small molecule | DB00302 | Details | |||
| D080 | Ertapenem | small molecule | DB00303 | Details | |||
| D081 | Mitomycin | small molecule | DB00305 | Details | |||
| D082 | Chlorthalidone | small molecule | DB00310 | Details | |||
| D083 | Valproic acid | small molecule | DB00313 | Details | |||
| D084 | Acetaminophen | small molecule | DB00316 | Details | |||
| D085 | Piperacillin | small molecule | DB00319 | Details | |||
| D086 | Amitriptyline | small molecule | DB00321 | Details | |||
| D087 | Nitroprusside | small molecule | DB00325 | Details | |||
| D088 | Indomethacin | small molecule | DB00328 | Details | |||
| D089 | Metformin | small molecule | DB00331 | Details | |||
| D090 | Methadone | small molecule | DB00333 | Details | |||
| D091 | Olanzapine | small molecule | DB00334 | Details | |||
| D092 | Atenolol | small molecule | DB00335 | Details | |||
| D093 | Cetirizine | small molecule | DB00341 | Details | |||
| D094 | Diltiazem | small molecule | DB00343 | Details | |||
| D095 | Minoxidil | small molecule | DB00350 | Details | |||
| D096 | Chlorzoxazone | small molecule | DB00356 | Details | |||
| D097 | Clozapine | small molecule | DB00363 | Details | |||
| D098 | Levonorgestrel | small molecule | DB00367 | Details | |||
| D099 | Norepinephrine | small molecule | DB00368 | Details | |||
| D100 | Cidofovir | small molecule | DB00369 | Details | |||
| D101 | Mirtazapine | small molecule | DB00370 | Details | |||
| D102 | Treprostinil | small molecule | DB00374 | Details | |||
| D103 | Dydrogesterone | small molecule | DB00378 | Details | |||
| D104 | Amlodipine | small molecule | DB00381 | Details | |||
| D105 | Triamterene | small molecule | DB00384 | Details | |||
| D106 | Phenylephrine | small molecule | DB00388 | Details | |||
| D107 | Digoxin | small molecule | DB00390 | Details | |||
| D108 | Nimodipine | small molecule | DB00393 | Details | |||
| D109 | Progesterone | small molecule | DB00396 | Details | |||
| D110 | Sorafenib | small molecule | DB00398 | Details | |||
| D111 | Zoledronic acid | small molecule | DB00399 | Details | |||
| D112 | Eszopiclone | small molecule | DB00402 | Details | |||
| D113 | Alprazolam | small molecule | DB00404 | Details | |||
| D114 | Loxapine | small molecule | DB00408 | Details | |||
| D115 | Mupirocin | small molecule | DB00410 | Details | |||
| D116 | Rosiglitazone | small molecule | DB00412 | Details | |||
| D117 | Acetohexamide | small molecule | DB00414 | Details | |||
| D118 | Ampicillin | small molecule | DB00415 | Details | |||
| D119 | Spironolactone | small molecule | DB00421 | Details | |||
| D120 | Methocarbamol | small molecule | DB00423 | Details | |||
| D121 | Zolpidem | small molecule | DB00425 | Details | |||
| D122 | Nitric Oxide | small molecule | DB00435 | Details | |||
| D123 | Ceftazidime | small molecule | DB00438 | Details | |||
| D124 | Trimethoprim | small molecule | DB00440 | Details | |||
| D125 | Betamethasone | small molecule | DB00443 | Details | |||
| D126 | Lansoprazole | small molecule | DB00448 | Details | |||
| D127 | Loratadine | small molecule | DB00455 | Details | |||
| D128 | Imipramine | small molecule | DB00458 | Details | |||
| D129 | Dronabinol | small molecule | DB00470 | Details | |||
| D130 | Montelukast | small molecule | DB00471 | Details | |||
| D131 | Fluoxetine | small molecule | DB00472 | Details | |||
| D132 | Duloxetine | small molecule | DB00476 | Details | |||
| D133 | Chlorpromazine | small molecule | DB00477 | Details | |||
| D134 | Amikacin | small molecule | DB00479 | Details | |||
| D135 | Lenalidomide | small molecule | DB00480 | Details | |||
| D136 | Celecoxib | small molecule | DB00482 | Details | |||
| D137 | Altretamine | small molecule | DB00488 | Details | |||
| D138 | Miglitol | small molecule | DB00491 | Details | |||
| D139 | Cefotaxime | small molecule | DB00493 | Details | |||
| D140 | Zidovudine | small molecule | DB00495 | Details | |||
| D141 | Oxycodone | small molecule | DB00497 | Details | |||
| D142 | Cimetidine | small molecule | DB00501 | Details | |||
| D143 | Ritonavir | small molecule | DB00503 | Details | |||
| D144 | Nitazoxanide | small molecule | DB00507 | Details | |||
| D145 | Vancomycin | small molecule | DB00512 | Details | |||
| D146 | Aminocaproic acid | small molecule | DB00513 | Details | |||
| D147 | Trandolapril | small molecule | DB00519 | Details | |||
| D148 | Metolazone | small molecule | DB00524 | Details | |||
| D149 | Tolnaftate | small molecule | DB00525 | Details | |||
| D150 | Lercanidipine | small molecule | DB00528 | Details | |||
| D151 | Cyclophosphamide | small molecule | DB00531 | Details | |||
| D152 | Ciprofloxacin | small molecule | DB00537 | Details | |||
| D153 | Benazepril | small molecule | DB00542 | Details | |||
| D154 | Propylthiouracil | small molecule | DB00550 | Details | |||
| D155 | Zanamivir | small molecule | DB00558 | Details | |||
| D156 | Bosentan | small molecule | DB00559 | Details | |||
| D157 | Methotrexate | small molecule | DB00563 | Details | |||
| D158 | Cisatracurium | small molecule | DB00565 | Details | |||
| D159 | Cephalexin | small molecule | DB00567 | Details | |||
| D160 | Propranolol | small molecule | DB00571 | Details | |||
| D161 | Atropine | small molecule | DB00572 | Details | |||
| D162 | Clonidine | small molecule | DB00575 | Details | |||
| D163 | Lactulose | small molecule | DB00581 | Details | |||
| D164 | Voriconazole | small molecule | DB00582 | Details | |||
| D165 | Diclofenac | small molecule | DB00586 | Details | |||
| D166 | Doxazosin | small molecule | DB00590 | Details | |||
| D167 | Amiloride | small molecule | DB00594 | Details | |||
| D168 | Labetalol | small molecule | DB00598 | Details | |||
| D169 | Thiopental | small molecule | DB00599 | Details | |||
| D170 | Linezolid | small molecule | DB00601 | Details | |||
| D171 | Cisapride | small molecule | DB00604 | Details | |||
| D172 | Nafcillin | small molecule | DB00607 | Details | |||
| D173 | Chloroquine | small molecule | DB00608 | Details | |||
| D174 | Bisoprolol | small molecule | DB00612 | Details | |||
| D175 | Fluphenazine | small molecule | DB00623 | Details | |||
| D176 | Testosterone | small molecule | DB00624 | Details | |||
| D177 | Efavirenz | small molecule | DB00625 | Details | |||
| D178 | Bacitracin | small molecule | DB00626 | Details | |||
| D179 | Niacin | small molecule | DB00627 | Details | |||
| D180 | Alendronic acid | small molecule | DB00630 | Details | |||
| D181 | Prednisone | small molecule | DB00635 | Details | |||
| D182 | Inulin | small molecule | DB00638 | Details | |||
| D183 | Adenosine | small molecule | DB00640 | Details | |||
| D184 | Simvastatin | small molecule | DB00641 | Details | |||
| D185 | Stavudine | small molecule | DB00649 | Details | |||
| D186 | Trazodone | small molecule | DB00656 | Details | |||
| D187 | Verapamil | small molecule | DB00661 | Details | |||
| D188 | Epinephrine | small molecule | DB00668 | Details | |||
| D189 | Pirenzepine | small molecule | DB00670 | Details | |||
| D190 | Cefixime | small molecule | DB00671 | Details | |||
| D191 | Chlorpropamide | small molecule | DB00672 | Details | |||
| D192 | Losartan | small molecule | DB00678 | Details | |||
| D193 | Thioridazine | small molecule | DB00679 | Details | |||
| D194 | Warfarin | small molecule | DB00682 | Details | |||
| D195 | Midazolam | small molecule | DB00683 | Details | |||
| D196 | Tobramycin | small molecule | DB00684 | Details | |||
| D197 | Fludrocortisone | small molecule | DB00687 | Details | |||
| D198 | Phentolamine | small molecule | DB00692 | Details | |||
| D199 | Furosemide | small molecule | DB00695 | Details | |||
| D200 | Eplerenone | small molecule | DB00700 | Details | |||
| D201 | Amprenavir | small molecule | DB00701 | Details | |||
| D202 | Naltrexone | small molecule | DB00704 | Details | |||
| D203 | Tamsulosin | small molecule | DB00706 | Details | |||
| D204 | Lamivudine | small molecule | DB00709 | Details | |||
| D205 | Ibandronate | small molecule | DB00710 | Details | |||
| D206 | Flurbiprofen | small molecule | DB00712 | Details | |||
| D207 | Oxacillin | small molecule | DB00713 | Details | |||
| D208 | Paroxetine | small molecule | DB00715 | Details | |||
| D209 | Lisinopril | small molecule | DB00722 | Details | |||
| D210 | Nitroglycerin | small molecule | DB00727 | Details | |||
| D211 | Rocuronium | small molecule | DB00728 | Details | |||
| D212 | Risperidone | small molecule | DB00734 | Details | |||
| D213 | Esomeprazole | small molecule | DB00736 | Details | |||
| D214 | Pentamidine | small molecule | DB00738 | Details | |||
| D215 | Hydrocortisone | small molecule | DB00741 | Details | |||
| D216 | Mannitol | small molecule | DB00742 | Details | |||
| D217 | Deferoxamine | small molecule | DB00746 | Details | |||
| D218 | Prilocaine | small molecule | DB00750 | Details | |||
| D219 | Isoflurane | small molecule | DB00753 | Details | |||
| D220 | Clopidogrel | small molecule | DB00758 | Details | |||
| D221 | Methimazole | small molecule | DB00763 | Details | |||
| D222 | Clavulanic acid | small molecule | DB00766 | Details | |||
| D223 | Alprostadil | small molecule | DB00770 | Details | |||
| D224 | Mefenamic acid | small molecule | DB00784 | Details | |||
| D225 | Perindopril | small molecule | DB00790 | Details | |||
| D226 | Alfentanil | small molecule | DB00802 | Details | |||
| D227 | Pentoxifylline | small molecule | DB00806 | Details | |||
| D228 | Indapamide | small molecule | DB00808 | Details | |||
| D229 | Tropicamide | small molecule | DB00809 | Details | |||
| D230 | Ribavirin | small molecule | DB00811 | Details | |||
| D231 | Fentanyl | small molecule | DB00813 | Details | |||
| D232 | Propofol | small molecule | DB00818 | Details | |||
| D233 | Acetazolamide | small molecule | DB00819 | Details | |||
| D234 | Tadalafil | small molecule | DB00820 | Details | |||
| D235 | Fosfomycin | small molecule | DB00828 | Details | |||
| D236 | Diazepam | small molecule | DB00829 | Details | |||
| D237 | Trifluoperazine | small molecule | DB00831 | Details | |||
| D238 | Mifepristone | small molecule | DB00834 | Details | |||
| D239 | Tolazamide | small molecule | DB00839 | Details | |||
| D240 | Dobutamine | small molecule | DB00841 | Details | |||
| D241 | Donepezil | small molecule | DB00843 | Details | |||
| D242 | Nalbuphine | small molecule | DB00844 | Details | |||
| D243 | Levamisole | small molecule | DB00848 | Details | |||
| D244 | Perphenazine | small molecule | DB00850 | Details | |||
| D245 | Pseudoephedrine | small molecule | DB00852 | Details | |||
| D246 | Aminolevulinic acid | small molecule | DB00855 | Details | |||
| D247 | Terbinafine | small molecule | DB00857 | Details | |||
| D248 | Prednisolone | small molecule | DB00860 | Details | |||
| D249 | Diflunisal | small molecule | DB00861 | Details | |||
| D250 | Terbutaline | small molecule | DB00871 | Details | |||
| D251 | Guaifenesin | small molecule | DB00874 | Details | |||
| D252 | Eprosartan | small molecule | DB00876 | Details | |||
| D253 | Sirolimus | small molecule | DB00877 | Details | |||
| D254 | Emtricitabine | small molecule | DB00879 | Details | |||
| D255 | Quinapril | small molecule | DB00881 | Details | |||
| D256 | Isosorbide dinitrate | small molecule | DB00883 | Details | |||
| D257 | Mechlorethamine | small molecule | DB00888 | Details | |||
| D258 | Ethanol | small molecule | DB00898 | Details | |||
| D259 | Remifentanil | small molecule | DB00899 | Details | |||
| D260 | Ondansetron | small molecule | DB00904 | Details | |||
| D261 | Cocaine | small molecule | DB00907 | Details | |||
| D262 | Repaglinide | small molecule | DB00912 | Details | |||
| D263 | Phenformin | small molecule | DB00914 | Details | |||
| D264 | Amantadine | small molecule | DB00915 | Details | |||
| D265 | Metronidazole | small molecule | DB00916 | Details | |||
| D266 | Dinoprostone | small molecule | DB00917 | Details | |||
| D267 | Buprenorphine | small molecule | DB00921 | Details | |||
| D268 | Azacitidine | small molecule | DB00928 | Details | |||
| D269 | Misoprostol | small molecule | DB00929 | Details | |||
| D270 | Mesoridazine | small molecule | DB00933 | Details | |||
| D271 | Oxymetazoline | small molecule | DB00935 | Details | |||
| D272 | Salicylic acid | small molecule | DB00936 | Details | |||
| D273 | Acetylsalicylic acid | small molecule | DB00945 | Details | |||
| D274 | Phenprocoumon | small molecule | DB00946 | Details | |||
| D275 | Fexofenadine | small molecule | DB00950 | Details | |||
| D276 | Isoniazid | small molecule | DB00951 | Details | |||
| D277 | Norgestimate | small molecule | DB00957 | Details | |||
| D278 | Methylprednisolone | small molecule | DB00959 | Details | |||
| D279 | Mepivacaine | small molecule | DB00961 | Details | |||
| D280 | Zaleplon | small molecule | DB00962 | Details | |||
| D281 | Bromfenac | small molecule | DB00963 | Details | |||
| D282 | Telmisartan | small molecule | DB00966 | Details | |||
| D283 | Methyldopa | small molecule | DB00968 | Details | |||
| D284 | Ezetimibe | small molecule | DB00973 | Details | |||
| D285 | Edetic acid | small molecule | DB00974 | Details | |||
| D286 | Dipyridamole | small molecule | DB00975 | Details | |||
| D287 | Ethinylestradiol | small molecule | DB00977 | Details | |||
| D288 | Physostigmine | small molecule | DB00981 | Details | |||
| D289 | Isotretinoin | small molecule | DB00982 | Details | |||
| D290 | Nandrolone phenpropionate | small molecule | DB00984 | Details | |||
| D291 | Glycopyrronium | small molecule | DB00986 | Details | |||
| D292 | Dopamine | small molecule | DB00988 | Details | |||
| D293 | Azathioprine | small molecule | DB00993 | Details | |||
| D294 | Gabapentin | small molecule | DB00996 | Details | |||
| D295 | Frovatriptan | small molecule | DB00998 | Details | |||
| D296 | Hydrochlorothiazide | small molecule | DB00999 | Details | |||
| D297 | Salbutamol | small molecule | DB01001 | Details | |||
| D298 | Levobupivacaine | small molecule | DB01002 | Details | |||
| D299 | Hydroxyurea | small molecule | DB01005 | Details | |||
| D300 | Letrozole | small molecule | DB01006 | Details | |||
| D301 | Metyrapone | small molecule | DB01011 | Details | |||
| D302 | Cinacalcet | small molecule | DB01012 | Details | |||
| D303 | Sulfamethoxazole | small molecule | DB01015 | Details | |||
| D304 | Bethanechol | small molecule | DB01019 | Details | |||
| D305 | Phylloquinone | small molecule | DB01022 | Details | |||
| D306 | Felodipine | small molecule | DB01023 | Details | |||
| D307 | Mycophenolic acid | small molecule | DB01024 | Details | |||
| D308 | Amlexanox | small molecule | DB01025 | Details | |||
| D309 | Irbesartan | small molecule | DB01029 | Details | |||
| D310 | Probenecid | small molecule | DB01032 | Details | |||
| D311 | Fenofibrate | small molecule | DB01039 | Details | |||
| D312 | Thalidomide | small molecule | DB01041 | Details | |||
| D313 | Ibuprofen | small molecule | DB01050 | Details | |||
| D314 | Benzylpenicillin | small molecule | DB01053 | Details | |||
| D315 | Amoxicillin | small molecule | DB01060 | Details | |||
| D316 | Melatonin | small molecule | DB01065 | Details | |||
| D317 | Glipizide | small molecule | DB01067 | Details | |||
| D318 | Promethazine | small molecule | DB01069 | Details | |||
| D319 | Diphenhydramine | small molecule | DB01075 | Details | |||
| D320 | Atorvastatin | small molecule | DB01076 | Details | |||
| D321 | Vigabatrin | small molecule | DB01080 | Details | |||
| D322 | Streptomycin | small molecule | DB01082 | Details | |||
| D323 | Orlistat | small molecule | DB01083 | Details | |||
| D324 | Pilocarpine | small molecule | DB01085 | Details | |||
| D325 | Benzocaine | small molecule | DB01086 | Details | |||
| D326 | Dimethyl sulfoxide | small molecule | DB01093 | Details | |||
| D327 | Pimozide | small molecule | DB01100 | Details | |||
| D328 | Sertraline | small molecule | DB01104 | Details | |||
| D329 | Miconazole | small molecule | DB01110 | Details | |||
| D330 | Nifedipine | small molecule | DB01115 | Details | |||
| D331 | Amiodarone | small molecule | DB01118 | Details | |||
| D332 | Diazoxide | small molecule | DB01119 | Details | |||
| D333 | Gliclazide | small molecule | DB01120 | Details | |||
| D334 | Tolbutamide | small molecule | DB01124 | Details | |||
| D335 | Dutasteride | small molecule | DB01126 | Details | |||
| D336 | Pioglitazone | small molecule | DB01132 | Details | |||
| D337 | Carvedilol | small molecule | DB01136 | Details | |||
| D338 | Levofloxacin | small molecule | DB01137 | Details | |||
| D339 | Cefadroxil | small molecule | DB01140 | Details | |||
| D340 | Bupropion | small molecule | DB01156 | Details | |||
| D341 | Terazosin | small molecule | DB01162 | Details | |||
| D342 | Ofloxacin | small molecule | DB01165 | Details | |||
| D343 | Cilostazol | small molecule | DB01166 | Details | |||
| D344 | Itraconazole | small molecule | DB01167 | Details | |||
| D345 | Chlormezanone | small molecule | DB01178 | Details | |||
| D346 | Naloxone | small molecule | DB01183 | Details | |||
| D347 | Domperidone | small molecule | DB01184 | Details | |||
| D348 | Ciclopirox | small molecule | DB01188 | Details | |||
| D349 | Desflurane | small molecule | DB01189 | Details | |||
| D350 | Clindamycin | small molecule | DB01190 | Details | |||
| D351 | Dexfenfluramine | small molecule | DB01191 | Details | |||
| D352 | Captopril | small molecule | DB01197 | Details | |||
| D353 | Zopiclone | small molecule | DB01198 | Details | |||
| D354 | Bromocriptine | small molecule | DB01200 | Details | |||
| D355 | Clarithromycin | small molecule | DB01211 | Details | |||
| D356 | Ceftriaxone | small molecule | DB01212 | Details | |||
| D357 | Anastrozole | small molecule | DB01217 | Details | |||
| D358 | Dantrolene | small molecule | DB01219 | Details | |||
| D359 | Budesonide | small molecule | DB01222 | Details | |||
| D360 | Quetiapine | small molecule | DB01224 | Details | |||
| D361 | Paclitaxel | small molecule | DB01229 | Details | |||
| D362 | Metoclopramide | small molecule | DB01233 | Details | |||
| D363 | Dexamethasone | small molecule | DB01234 | Details | |||
| D364 | Sevoflurane | small molecule | DB01236 | Details | |||
| D365 | Aripiprazole | small molecule | DB01238 | Details | |||
| D366 | Epoprostenol | small molecule | DB01240 | Details | |||
| D367 | Gliquidone | small molecule | DB01251 | Details | |||
| D368 | Dasatinib | small molecule | DB01254 | Details | |||
| D369 | Lapatinib | small molecule | DB01259 | Details | |||
| D370 | Darunavir | small molecule | DB01264 | Details | |||
| D371 | Sunitinib | small molecule | DB01268 | Details | |||
| D372 | Hydralazine | small molecule | DB01275 | Details | |||
| D373 | Lumiracoxib | small molecule | DB01283 | Details | |||
| D374 | Glucosamine | small molecule | DB01296 | Details | |||
| D375 | Cefazolin | small molecule | DB01327 | Details | |||
| D376 | Vecuronium | small molecule | DB01339 | Details | |||
| D377 | Cilazapril | small molecule | DB01340 | Details | |||
| D378 | Spirapril | small molecule | DB01348 | Details | |||
| D379 | Ephedrine | small molecule | DB01364 | Details | |||
| D380 | Yohimbine | small molecule | DB01392 | Details | |||
| D381 | Bezafibrate | small molecule | DB01393 | Details | |||
| D382 | Colchicine | small molecule | DB01394 | Details | |||
| D383 | Drospirenone | small molecule | DB01395 | Details | |||
| D384 | Methotrimeprazine | small molecule | DB01403 | Details | |||
| D385 | Clenbuterol | small molecule | DB01407 | Details | |||
| D386 | Theobromine | small molecule | DB01412 | Details | |||
| D387 | Cefepime | small molecule | DB01413 | Details | |||
| D388 | Alfacalcidol | small molecule | DB01436 | Details | |||
| D389 | Diamorphine | small molecule | DB01452 | Details | |||
| D390 | Metamfetamine | small molecule | DB01577 | Details | |||
| D391 | Sulfamethazine | small molecule | DB01582 | Details | |||
| D392 | Ursodeoxycholic acid | small molecule | DB01586 | Details | |||
| D393 | Probucol | small molecule | DB01599 | Details | |||
| D394 | Lopinavir | small molecule | DB01601 | Details | |||
| D395 | Tazobactam | small molecule | DB01606 | Details | |||
| D396 | Hydroxychloroquine | small molecule | DB01611 | Details | |||
| D397 | Molindone | small molecule | DB01618 | Details | |||
| D398 | Thiothixene | small molecule | DB01623 | Details | |||
| D399 | Sorbitol | small molecule | DB01638 | Details | |||
| D400 | Genistein | small molecule | DB01645 | Details | |||
| D401 | N,N-dimethylarginine | small molecule | DB01686 | Details | |||
| D402 | Prasterone | small molecule | DB01708 | Details | |||
| D403 | Pantothenic acid | small molecule | DB01783 | Details | |||
| D404 | Taurine | small molecule | DB01956 | Details | |||
| D405 | Calcipotriol | small molecule | DB02300 | Details | |||
| D406 | Thymol | small molecule | DB02513 | Details | |||
| D407 | gamma-Aminobutyric acid | small molecule | DB02530 | Details | |||
| D408 | Terlipressin | small molecule | DB02638 | Details | |||
| D409 | Nicotinamide | small molecule | DB02701 | Details | |||
| D410 | Fusidic acid | small molecule | DB02703 | Details | |||
| D411 | Resveratrol | small molecule | DB02709 | Details | |||
| D412 | Oxitriptan | small molecule | DB02959 | Details | |||
| D413 | Glycolic acid | small molecule | DB03085 | Details | |||
| D414 | Acetylcholine | small molecule | DB03128 | Details | |||
| D415 | Acetic acid | small molecule | DB03166 | Details | |||
| D416 | Phenol | small molecule | DB03255 | Details | |||
| D417 | Palmitic Acid | small molecule | DB03796 | Details | |||
| D418 | Eucalyptol | small molecule | DB03852 | Details | |||
| D419 | Citric acid | small molecule | DB04272 | Details | |||
| D420 | Maleic Acid | small molecule | DB04299 | Details | |||
| D421 | N,N,N-trimethylglycinium | small molecule | DB04455 | Details | |||
| D422 | Meso-Erythritol | small molecule | DB04481 | Details | |||
| D423 | Indole | small molecule | DB04532 | Details | |||
| D424 | Arachidonic Acid | small molecule | DB04557 | Details | |||
| D425 | Buformin | small molecule | DB04830 | Details | |||
| D426 | Methaqualone | small molecule | DB04833 | Details | |||
| D427 | Cyproterone acetate | small molecule | DB04839 | Details | |||
| D428 | Fluspirilene | small molecule | DB04842 | Details | |||
| D429 | Tetrabenazine | small molecule | DB04844 | Details | |||
| D430 | Febuxostat | small molecule | DB04854 | Details | |||
| D431 | Nebivolol | small molecule | DB04861 | Details | |||
| D432 | Vildagliptin | small molecule | DB04876 | Details | |||
| D433 | Voglibose | small molecule | DB04878 | Details | |||
| D434 | Iloperidone | small molecule | DB04946 | Details | |||
| D435 | Lobeline | small molecule | DB05137 | Details | |||
| D436 | Histamine | small molecule | DB05381 | Details | |||
| D437 | Iodine | small molecule | DB05382 | Details | |||
| D438 | Levoketoconazole | small molecule | DB05667 | Details | |||
| D439 | Acetylcysteine | small molecule | DB06151 | Details | |||
| D440 | Atrasentan | small molecule | DB06199 | Details | |||
| D441 | Rivaroxaban | small molecule | DB06228 | Details | |||
| D442 | Eflornithine | small molecule | DB06243 | Details | |||
| D443 | Sitaxentan | small molecule | DB06268 | Details | |||
| D444 | Amisulpride | small molecule | DB06288 | Details | |||
| D445 | Dapagliflozin | small molecule | DB06292 | Details | |||
| D446 | Darapladib | small molecule | DB06311 | Details | |||
| D447 | Saxagliptin | small molecule | DB06335 | Details | |||
| D448 | Ambrisentan | small molecule | DB06403 | Details | |||
| D449 | Etravirine | small molecule | DB06414 | Details | |||
| D450 | Prucalopride | small molecule | DB06480 | Details | |||
| D451 | Cetilistat | small molecule | DB06586 | Details | |||
| D452 | Agomelatine | small molecule | DB06594 | Details | |||
| D453 | Apixaban | small molecule | DB06605 | Details | |||
| D454 | Bosutinib | small molecule | DB06616 | Details | |||
| D455 | Desvenlafaxine | small molecule | DB06700 | Details | |||
| D456 | Methyltestosterone | small molecule | DB06710 | Details | |||
| D457 | Beta carotene | small molecule | DB06755 | Details | |||
| D458 | Manganese | small molecule | DB06757 | Details | |||
| D459 | Capsaicin | small molecule | DB06774 | Details | |||
| D460 | Chenodeoxycholic acid | small molecule | DB06777 | Details | |||
| D461 | Cupric sulfate | small molecule | DB06778 | Details | |||
| D462 | Lanreotide | small molecule | DB06791 | Details | |||
| D463 | Plerixafor | small molecule | DB06809 | Details | |||
| D464 | Phenylbutyric acid | small molecule | DB06819 | Details | |||
| D465 | 4,4'-PROPANE-2,2-DIYLDIPHENOL | small molecule | DB06973 | Details | |||
| D466 | Emodin | small molecule | DB07715 | Details | |||
| D467 | 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE | small molecule | DB07919 | Details | |||
| D468 | Parecoxib | small molecule | DB08439 | Details | |||
| D469 | Triclosan | small molecule | DB08604 | Details | |||
| D470 | Nandrolone decanoate | small molecule | DB08804 | Details | |||
| D471 | Ticagrelor | small molecule | DB08816 | Details | |||
| D472 | Deferiprone | small molecule | DB08826 | Details | |||
| D473 | Uric acid | small molecule | DB08844 | Details | |||
| D474 | Pitavastatin | small molecule | DB08860 | Details | |||
| D475 | Rilpivirine | small molecule | DB08864 | Details | |||
| D476 | Linaclotide | small molecule | DB08890 | Details | |||
| D477 | Tofacitinib | small molecule | DB08895 | Details | |||
| D478 | Dimethyl fumarate | small molecule | DB08908 | Details | |||
| D479 | Sofosbuvir | small molecule | DB08934 | Details | |||
| D480 | Dexetimide | small molecule | DB08997 | Details | |||
| D481 | Bisacodyl | small molecule | DB09020 | Details | |||
| D482 | Aliskiren | small molecule | DB09026 | Details | |||
| D483 | Ledipasvir | small molecule | DB09027 | Details | |||
| D484 | Acipimox | small molecule | DB09055 | Details | |||
| D485 | Ciprofibrate | small molecule | DB09064 | Details | |||
| D486 | Olaparib | small molecule | DB09074 | Details | |||
| D487 | Benzoyl peroxide | small molecule | DB09096 | Details | |||
| D488 | Coenzyme M | small molecule | DB09110 | Details | |||
| D489 | Nicorandil | small molecule | DB09220 | Details | |||
| D490 | Manidipine | small molecule | DB09238 | Details | |||
| D491 | Methylene blue | small molecule | DB09241 | Details | |||
| D492 | Moxonidine | small molecule | DB09242 | Details | |||
| D493 | Ubidecarenone | small molecule | DB09270 | Details | |||
| D494 | Silibinin | small molecule | DB09298 | Details | |||
| D495 | Glycerin | small molecule | DB09462 | Details | |||
| D496 | Methyl salicylate | small molecule | DB09543 | Details | |||
| D497 | Ixazomib | small molecule | DB09570 | Details | |||
| D498 | Hydrogen peroxide | small molecule | DB11091 | Details | |||
| D499 | Lycopene | small molecule | DB11231 | Details | |||
| D500 | Medetomidine | small molecule | DB11428 | Details | |||
| D501 | Lesinurad | small molecule | DB11560 | Details | |||
| D502 | Carbon monoxide | small molecule | DB11588 | Details | |||
| D503 | Curcumin | small molecule | DB11672 | Details | |||
| D504 | Pyridoxamine | small molecule | DB11673 | Details | |||
| D505 | Equol | small molecule | DB11674 | Details | |||
| D506 | Mosapride | small molecule | DB11675 | Details | |||
| D507 | Ebastine | small molecule | DB11742 | Details | |||
| D508 | Rifamycin | small molecule | DB11753 | Details | |||
| D509 | Imidapril | small molecule | DB11783 | Details | |||
| D510 | Angiotensin II | small molecule | DB11842 | Details | |||
| D511 | Verinurad | small molecule | DB11873 | Details | |||
| D512 | 2,4-thiazolidinedione | small molecule | DB11898 | Details | |||
| D513 | Zuretinol acetate | small molecule | DB12112 | Details | |||
| D514 | Bradykinin | small molecule | DB12126 | Details | |||
| D515 | Sarpogrelate | small molecule | DB12163 | Details | |||
| D516 | Secoisolariciresinol | small molecule | DB12179 | Details | |||
| D517 | Bexagliflozin | small molecule | DB12236 | Details | |||
| D518 | Benzbromarone | small molecule | DB12319 | Details | |||
| D519 | Nitroaspirin | small molecule | DB12445 | Details | |||
| D520 | Piperine | small molecule | DB12582 | Details | |||
| D521 | Isoquercetin | small molecule | DB12665 | Details | |||
| D522 | Cicletanine | small molecule | DB12766 | Details | |||
| D523 | Gallopamil | small molecule | DB12923 | Details | |||
| D524 | Lactitol | small molecule | DB12942 | Details | |||
| D525 | Daidzein | small molecule | DB13182 | Details | |||
| D526 | Camostat | small molecule | DB13729 | Details | |||
| D527 | Fenofibric acid | small molecule | DB13873 | Details | |||
| D528 | Candesartan | small molecule | DB13919 | Details | |||
| D529 | Testosterone enanthate | small molecule | DB13944 | Details | |||
| D530 | Ferric cation | small molecule | DB13949 | Details | |||
| D531 | Palmidrol | small molecule | DB14043 | Details | |||
| D532 | Cianidanol | small molecule | DB14086 | Details | |||
| D533 | Tenofovir | small molecule | DB14126 | Details | |||
| D534 | Cinnamaldehyde | small molecule | DB14184 | Details | |||
| D535 | Cobaltous cation | small molecule | DB14205 | Details | |||
| D536 | Chromic cation | small molecule | DB14525 | Details | |||
| D537 | Zinc cation | small molecule | DB14532 | Details | |||
| D538 | Cupric cation | small molecule | DB14552 | Details | |||
| D539 | Bismuth cation | small molecule | DB14572 | Details | |||
| D540 | Calcium cation | small molecule | DB14577 | Details | |||
| D541 | Cortisone | small molecule | DB14681 | Details | |||
| D542 | Dabigatran | small molecule | DB14726 | Details | |||
| D543 | Remdesivir | small molecule | DB14761 | Details | |||
| D544 | Venglustat | small molecule | DB14966 | Details | |||
| D545 | Abrocitinib | small molecule | DB14973 | Details | |||
| D546 | Ursolic acid | small molecule | DB15588 | Details |